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The immune privilege of testis and gravid Uterus: same difference?

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The immune privilege of testis and gravid Uterus: same difference? / Arck, Petra; Solano, María Emilia; Walecki, Magdalena; Meinhardt, Andreas.

In: MOL CELL ENDOCRINOL, Vol. 382, No. 1, 25.01.2014, p. 509-20.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Arck, P, Solano, ME, Walecki, M & Meinhardt, A 2014, 'The immune privilege of testis and gravid Uterus: same difference?', MOL CELL ENDOCRINOL, vol. 382, no. 1, pp. 509-20. https://doi.org/10.1016/j.mce.2013.09.022

APA

Arck, P., Solano, M. E., Walecki, M., & Meinhardt, A. (2014). The immune privilege of testis and gravid Uterus: same difference? MOL CELL ENDOCRINOL, 382(1), 509-20. https://doi.org/10.1016/j.mce.2013.09.022

Vancouver

Arck P, Solano ME, Walecki M, Meinhardt A. The immune privilege of testis and gravid Uterus: same difference? MOL CELL ENDOCRINOL. 2014 Jan 25;382(1):509-20. https://doi.org/10.1016/j.mce.2013.09.022

Bibtex

@article{5e5c02bddd914bc492e412da410f7321,
title = "The immune privilege of testis and gravid Uterus: same difference?",
abstract = "The fetus in the gravid uterus and the developing spermatogenic cells in the adult testis both comprise special challenges for the host immune system. Protection of the neoantigens of the fetus and male germ cells from immune attack, defined as immune privilege, is fundamental for the propagation of species. Immune privilege is not simply the absence of leukocytes, but involves immune and non-immune cells acting synergistically together at multiple levels to create a unique tolerogenic environment. A number of the pathways are shared by the testis and gravid uterus. Amongst them steroid hormones, namely testosterone in the male and progesterone in the female, seem to function as key molecules that govern the local production of immunoregulatory factors which finally control the overall immune environment.",
author = "Petra Arck and Solano, {Mar{\'i}a Emilia} and Magdalena Walecki and Andreas Meinhardt",
note = "Copyright {\textcopyright} 2013 Elsevier Ireland Ltd. All rights reserved.",
year = "2014",
month = jan,
day = "25",
doi = "10.1016/j.mce.2013.09.022",
language = "English",
volume = "382",
pages = "509--20",
journal = "MOL CELL ENDOCRINOL",
issn = "0303-7207",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - The immune privilege of testis and gravid Uterus: same difference?

AU - Arck, Petra

AU - Solano, María Emilia

AU - Walecki, Magdalena

AU - Meinhardt, Andreas

N1 - Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

PY - 2014/1/25

Y1 - 2014/1/25

N2 - The fetus in the gravid uterus and the developing spermatogenic cells in the adult testis both comprise special challenges for the host immune system. Protection of the neoantigens of the fetus and male germ cells from immune attack, defined as immune privilege, is fundamental for the propagation of species. Immune privilege is not simply the absence of leukocytes, but involves immune and non-immune cells acting synergistically together at multiple levels to create a unique tolerogenic environment. A number of the pathways are shared by the testis and gravid uterus. Amongst them steroid hormones, namely testosterone in the male and progesterone in the female, seem to function as key molecules that govern the local production of immunoregulatory factors which finally control the overall immune environment.

AB - The fetus in the gravid uterus and the developing spermatogenic cells in the adult testis both comprise special challenges for the host immune system. Protection of the neoantigens of the fetus and male germ cells from immune attack, defined as immune privilege, is fundamental for the propagation of species. Immune privilege is not simply the absence of leukocytes, but involves immune and non-immune cells acting synergistically together at multiple levels to create a unique tolerogenic environment. A number of the pathways are shared by the testis and gravid uterus. Amongst them steroid hormones, namely testosterone in the male and progesterone in the female, seem to function as key molecules that govern the local production of immunoregulatory factors which finally control the overall immune environment.

U2 - 10.1016/j.mce.2013.09.022

DO - 10.1016/j.mce.2013.09.022

M3 - SCORING: Journal article

C2 - 24076096

VL - 382

SP - 509

EP - 520

JO - MOL CELL ENDOCRINOL

JF - MOL CELL ENDOCRINOL

SN - 0303-7207

IS - 1

ER -