The effect of depressive symptoms on quality of life and its different facets in the oldest age population: evidence from the AgeQualiDe prospective cohort study

  • Paula Liegert
  • Alexander Pabst
  • Ines Conrad
  • Hendrik van den Bussche
  • Marion Eisele
  • André Hajek
  • Kathrin Heser
  • Luca Kleineidam
  • Siegfried Weyerer
  • Jochen Werle
  • Michael Pentzek
  • Dagmar Weeg
  • Edelgard Mösch
  • Birgitt Wiese
  • Anke Oey
  • Michael Wagner
  • Wolfgang Maier
  • Hans-Helmut König
  • Steffi G Riedel-Heller
  • Martin Scherer (Shared last author)
  • Melanie Luppa (Shared last author)

Abstract

PURPOSE: The present study aims to investigate the prospective effect of depressive symptoms on overall QoL in the oldest age group, taking into account its different facets.

METHODS: Data were derived from the multicenter prospective AgeCoDe/AgeQualiDe cohort study, including data from follow-up 7-9 and n = 580 individuals 85 years of age and older. Overall QoL and its facets were assessed using the WHOQOL-OLD instrument. The short form of the geriatric depression scale (GDS-15) was applied to assess depressive symptoms. Cognitively impaired individuals were excluded. Linear mixed-effects models were used to assess the effect of depressive symptoms on QoL.

RESULTS: Depressive symptoms were significantly associated with overall QoL and each of the different facets of WHOQOL-OLD, also after adjustment for time and sociodemographic characteristics such as age, gender, education, marital status, living situation, and cognitive status. Higher age and single as well as divorced marital status were also associated with a lower QoL.

CONCLUSION: This work provides comprehensive longitudinal results on the relationship between depressive symptoms and QoL in the oldest age population. The results underscore the relevance of tailored and targeted care planning and the development of customized interventions.

Bibliographical data

Original languageEnglish
ISSN0962-9343
DOIs
Publication statusPublished - 02.2024

Comment Deanary

© 2023. The Author(s).

PubMed 37897642

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