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The effect of AB0 and Rhesus blood grouping systems on oncological outcome in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma

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The effect of AB0 and Rhesus blood grouping systems on oncological outcome in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma. / Rink, Michael; Engel, Oliver; Gakis, Georgios; Fritsche, Hans Martin; Vetterlein, Malte W; Soave, Armin; Peine, Sven; Aziz, Atiqullah; Dahlem, Roland; Stenzl, Arnulf; Burger, Maximilian; Shariat, Shahrokh F; Fisch, Margit; Gild, Philipp.

In: UROL ONCOL-SEMIN ORI, Vol. 35, No. 12, 12.2017, p. 671.e17-671.e23.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Rink, M, Engel, O, Gakis, G, Fritsche, HM, Vetterlein, MW, Soave, A, Peine, S, Aziz, A, Dahlem, R, Stenzl, A, Burger, M, Shariat, SF, Fisch, M & Gild, P 2017, 'The effect of AB0 and Rhesus blood grouping systems on oncological outcome in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma', UROL ONCOL-SEMIN ORI, vol. 35, no. 12, pp. 671.e17-671.e23. https://doi.org/10.1016/j.urolonc.2017.08.007

APA

Rink, M., Engel, O., Gakis, G., Fritsche, H. M., Vetterlein, M. W., Soave, A., Peine, S., Aziz, A., Dahlem, R., Stenzl, A., Burger, M., Shariat, S. F., Fisch, M., & Gild, P. (2017). The effect of AB0 and Rhesus blood grouping systems on oncological outcome in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma. UROL ONCOL-SEMIN ORI, 35(12), 671.e17-671.e23. https://doi.org/10.1016/j.urolonc.2017.08.007

Vancouver

Rink M, Engel O, Gakis G, Fritsche HM, Vetterlein MW, Soave A et al. The effect of AB0 and Rhesus blood grouping systems on oncological outcome in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma. UROL ONCOL-SEMIN ORI. 2017 Dec;35(12):671.e17-671.e23. https://doi.org/10.1016/j.urolonc.2017.08.007

Bibtex

@article{d4c3a464439d48cead8e24e306305cc6,
title = "The effect of AB0 and Rhesus blood grouping systems on oncological outcome in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma",
abstract = "OBJECTIVES: To investigate the effect of AB0 and Rhesus factor expression blood group systems on outcomes of upper tract urothelial carcinoma patients treated with radical nephroureterectomy.PATIENTS AND METHODS: We analyzed data from 271 patients with upper tract urothelial carcinoma who underwent radical nephroureterectomy at 3 German academic institutions. Cox and logistic regression models assessed the association of AB0 blood group antigen and Rhesus factor expression with tumor biologic features and outcomes, respectively.RESULTS: In total, 119 patients (43.9%) had blood group antigen A0, 42 patients (15.4%) antigen B0, 15 patients (5.5%) antigen AB, and 95 patients (35.0%) the antigen 00. A total of 231 patients (85.2%) were Rhesus factor positive. The AB0 blood group antigen expression was associated with a higher tumor grade (P = 0.049) and sessile tumor architecture (P = 0.019). Both, AB0 blood group system and Rhesus factor expression, were associated with worse performance status (P = 0.024, and P = 0.003, respectively). In contrast, Rhesus factor expression status was not associated with any clinicopathologic characteristics. Neither the AB0 blood group antigens nor the Rhesus factor was associated with survival.CONCLUSION: AB0 blood group antigens and Rhesus factor expression are not associated with survival. The association of the AB0 blood group antigens with adverse pathological features warrants further validation.",
keywords = "Journal Article",
author = "Michael Rink and Oliver Engel and Georgios Gakis and Fritsche, {Hans Martin} and Vetterlein, {Malte W} and Armin Soave and Sven Peine and Atiqullah Aziz and Roland Dahlem and Arnulf Stenzl and Maximilian Burger and Shariat, {Shahrokh F} and Margit Fisch and Philipp Gild",
note = "Copyright {\textcopyright} 2017 Elsevier Inc. All rights reserved.",
year = "2017",
month = dec,
doi = "10.1016/j.urolonc.2017.08.007",
language = "English",
volume = "35",
pages = "671.e17--671.e23",
journal = "UROL ONCOL-SEMIN ORI",
issn = "1078-1439",
publisher = "Elsevier Inc.",
number = "12",

}

RIS

TY - JOUR

T1 - The effect of AB0 and Rhesus blood grouping systems on oncological outcome in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma

AU - Rink, Michael

AU - Engel, Oliver

AU - Gakis, Georgios

AU - Fritsche, Hans Martin

AU - Vetterlein, Malte W

AU - Soave, Armin

AU - Peine, Sven

AU - Aziz, Atiqullah

AU - Dahlem, Roland

AU - Stenzl, Arnulf

AU - Burger, Maximilian

AU - Shariat, Shahrokh F

AU - Fisch, Margit

AU - Gild, Philipp

N1 - Copyright © 2017 Elsevier Inc. All rights reserved.

PY - 2017/12

Y1 - 2017/12

N2 - OBJECTIVES: To investigate the effect of AB0 and Rhesus factor expression blood group systems on outcomes of upper tract urothelial carcinoma patients treated with radical nephroureterectomy.PATIENTS AND METHODS: We analyzed data from 271 patients with upper tract urothelial carcinoma who underwent radical nephroureterectomy at 3 German academic institutions. Cox and logistic regression models assessed the association of AB0 blood group antigen and Rhesus factor expression with tumor biologic features and outcomes, respectively.RESULTS: In total, 119 patients (43.9%) had blood group antigen A0, 42 patients (15.4%) antigen B0, 15 patients (5.5%) antigen AB, and 95 patients (35.0%) the antigen 00. A total of 231 patients (85.2%) were Rhesus factor positive. The AB0 blood group antigen expression was associated with a higher tumor grade (P = 0.049) and sessile tumor architecture (P = 0.019). Both, AB0 blood group system and Rhesus factor expression, were associated with worse performance status (P = 0.024, and P = 0.003, respectively). In contrast, Rhesus factor expression status was not associated with any clinicopathologic characteristics. Neither the AB0 blood group antigens nor the Rhesus factor was associated with survival.CONCLUSION: AB0 blood group antigens and Rhesus factor expression are not associated with survival. The association of the AB0 blood group antigens with adverse pathological features warrants further validation.

AB - OBJECTIVES: To investigate the effect of AB0 and Rhesus factor expression blood group systems on outcomes of upper tract urothelial carcinoma patients treated with radical nephroureterectomy.PATIENTS AND METHODS: We analyzed data from 271 patients with upper tract urothelial carcinoma who underwent radical nephroureterectomy at 3 German academic institutions. Cox and logistic regression models assessed the association of AB0 blood group antigen and Rhesus factor expression with tumor biologic features and outcomes, respectively.RESULTS: In total, 119 patients (43.9%) had blood group antigen A0, 42 patients (15.4%) antigen B0, 15 patients (5.5%) antigen AB, and 95 patients (35.0%) the antigen 00. A total of 231 patients (85.2%) were Rhesus factor positive. The AB0 blood group antigen expression was associated with a higher tumor grade (P = 0.049) and sessile tumor architecture (P = 0.019). Both, AB0 blood group system and Rhesus factor expression, were associated with worse performance status (P = 0.024, and P = 0.003, respectively). In contrast, Rhesus factor expression status was not associated with any clinicopathologic characteristics. Neither the AB0 blood group antigens nor the Rhesus factor was associated with survival.CONCLUSION: AB0 blood group antigens and Rhesus factor expression are not associated with survival. The association of the AB0 blood group antigens with adverse pathological features warrants further validation.

KW - Journal Article

U2 - 10.1016/j.urolonc.2017.08.007

DO - 10.1016/j.urolonc.2017.08.007

M3 - SCORING: Journal article

C2 - 28889922

VL - 35

SP - 671.e17-671.e23

JO - UROL ONCOL-SEMIN ORI

JF - UROL ONCOL-SEMIN ORI

SN - 1078-1439

IS - 12

ER -