Research ExplorerPublicationsThe E670G SNP in the PCSK9 gene is associated with polygenic...

The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women.

Standard

The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women. / Evans, David; Beil, Frank U.

In: BMC MED GENET, Vol. 7, 2006, p. 66.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Evans, D & Beil, FU 2006, 'The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women.', BMC MED GENET, vol. 7, pp. 66. https://doi.org/10.1186/1471-2350-7-66

APA

Evans, D., & Beil, F. U. (2006). The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women. BMC MED GENET, 7, 66. https://doi.org/10.1186/1471-2350-7-66

Vancouver

Evans D, Beil FU. The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women. BMC MED GENET. 2006;7:66. https://doi.org/10.1186/1471-2350-7-66

Bibtex

@article{6f18def4d27e4e1599ed2708d5a9b103,
title = "The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women.",
abstract = "BACKGROUND: Common genetic variants in the PCSK9 gene have been reported to be associated with both elevated and exceptionally low LDL levels. The association of a common haplotype, encompassing the E670G single nucleotide polymorphism, with LDL levels reported by Chen et al (J Am Coll Cardiol 2005; 45: 1644) was not confirmed by Kotowski et al (Am J Hum Genet 2006; 78:410-422). METHODS: The incidence of the E670G SNP was determined in 506 patients attending the lipid clinic, University Hospital, Hamburg. RESULTS: The frequency in men with polygenic hypercholesterolemia, 0.11 was significantly higher than in men with LDL",
author = "David Evans and Beil, {Frank U}",
year = "2006",
doi = "10.1186/1471-2350-7-66",
language = "Deutsch",
volume = "7",
pages = "66",
journal = "BMC MED GENET",
issn = "1471-2350",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women.

AU - Evans, David

AU - Beil, Frank U

PY - 2006

Y1 - 2006

N2 - BACKGROUND: Common genetic variants in the PCSK9 gene have been reported to be associated with both elevated and exceptionally low LDL levels. The association of a common haplotype, encompassing the E670G single nucleotide polymorphism, with LDL levels reported by Chen et al (J Am Coll Cardiol 2005; 45: 1644) was not confirmed by Kotowski et al (Am J Hum Genet 2006; 78:410-422). METHODS: The incidence of the E670G SNP was determined in 506 patients attending the lipid clinic, University Hospital, Hamburg. RESULTS: The frequency in men with polygenic hypercholesterolemia, 0.11 was significantly higher than in men with LDL

AB - BACKGROUND: Common genetic variants in the PCSK9 gene have been reported to be associated with both elevated and exceptionally low LDL levels. The association of a common haplotype, encompassing the E670G single nucleotide polymorphism, with LDL levels reported by Chen et al (J Am Coll Cardiol 2005; 45: 1644) was not confirmed by Kotowski et al (Am J Hum Genet 2006; 78:410-422). METHODS: The incidence of the E670G SNP was determined in 506 patients attending the lipid clinic, University Hospital, Hamburg. RESULTS: The frequency in men with polygenic hypercholesterolemia, 0.11 was significantly higher than in men with LDL

U2 - 10.1186/1471-2350-7-66

DO - 10.1186/1471-2350-7-66

M3 - SCORING: Zeitschriftenaufsatz

VL - 7

SP - 66

JO - BMC MED GENET

JF - BMC MED GENET

SN - 1471-2350

ER -