The Clinical Decision Support System AMPEL for Laboratory Diagnostics: Implementation and Technical Evaluation
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The Clinical Decision Support System AMPEL for Laboratory Diagnostics: Implementation and Technical Evaluation. / Walter Costa, Maria Beatriz; Wernsdorfer, Mark; Kehrer, Alexander; Voigt, Markus; Cundius, Carina; Federbusch, Martin; Eckelt, Felix; Remmler, Johannes; Schmidt, Maria; Pehnke, Sarah; Gärtner, Christiane; Wehner, Markus; Isermann, Berend; Richter, Heike; Telle, Jörg; Kaiser, Thorsten.
In: JMIR MED INF, Vol. 9, No. 6, e20407, 03.06.2021, p. e20407.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - The Clinical Decision Support System AMPEL for Laboratory Diagnostics: Implementation and Technical Evaluation
AU - Walter Costa, Maria Beatriz
AU - Wernsdorfer, Mark
AU - Kehrer, Alexander
AU - Voigt, Markus
AU - Cundius, Carina
AU - Federbusch, Martin
AU - Eckelt, Felix
AU - Remmler, Johannes
AU - Schmidt, Maria
AU - Pehnke, Sarah
AU - Gärtner, Christiane
AU - Wehner, Markus
AU - Isermann, Berend
AU - Richter, Heike
AU - Telle, Jörg
AU - Kaiser, Thorsten
N1 - ePaper.
PY - 2021/6/3
Y1 - 2021/6/3
N2 - Background: Laboratory results are of central importance for clinical decision making. The time span between availability and review of results by clinicians is crucial to patient care. Clinical decision support systems (CDSS) are computational tools that can identify critical values automatically and help decrease treatment delay.Objective: With this work, we aimed to implement and evaluate a CDSS that supports health care professionals and improves patient safety. In addition to our experiences, we also describe its main components in a general manner to make it applicable to a wide range of medical institutions and to empower colleagues to implement a similar system in their facilities.Methods: Technical requirements must be taken into account before implementing a CDSS that performs laboratory diagnostics (labCDSS). These can be planned within the functional components of a reactive software agent, a computational framework for such a CDSS.Results: We present AMPEL (Analysis and Reporting System for the Improvement of Patient Safety through Real-Time Integration of Laboratory Findings), a labCDSS that notifies health care professionals if a life-threatening medical condition is detected. We developed and implemented AMPEL at a university hospital and regional hospitals in Germany (University of Leipzig Medical Center and the Muldental Clinics in Grimma and Wurzen). It currently runs 5 different algorithms in parallel: hypokalemia, hypercalcemia, hyponatremia, hyperlactatemia, and acute kidney injury.Conclusions: AMPEL enables continuous surveillance of patients. The system is constantly being evaluated and extended and has the capacity for many more algorithms. We hope to encourage colleagues from other institutions to design and implement similar CDSS using the theory, specifications, and experiences described in this work.
AB - Background: Laboratory results are of central importance for clinical decision making. The time span between availability and review of results by clinicians is crucial to patient care. Clinical decision support systems (CDSS) are computational tools that can identify critical values automatically and help decrease treatment delay.Objective: With this work, we aimed to implement and evaluate a CDSS that supports health care professionals and improves patient safety. In addition to our experiences, we also describe its main components in a general manner to make it applicable to a wide range of medical institutions and to empower colleagues to implement a similar system in their facilities.Methods: Technical requirements must be taken into account before implementing a CDSS that performs laboratory diagnostics (labCDSS). These can be planned within the functional components of a reactive software agent, a computational framework for such a CDSS.Results: We present AMPEL (Analysis and Reporting System for the Improvement of Patient Safety through Real-Time Integration of Laboratory Findings), a labCDSS that notifies health care professionals if a life-threatening medical condition is detected. We developed and implemented AMPEL at a university hospital and regional hospitals in Germany (University of Leipzig Medical Center and the Muldental Clinics in Grimma and Wurzen). It currently runs 5 different algorithms in parallel: hypokalemia, hypercalcemia, hyponatremia, hyperlactatemia, and acute kidney injury.Conclusions: AMPEL enables continuous surveillance of patients. The system is constantly being evaluated and extended and has the capacity for many more algorithms. We hope to encourage colleagues from other institutions to design and implement similar CDSS using the theory, specifications, and experiences described in this work.
U2 - 10.2196/20407
DO - 10.2196/20407
M3 - SCORING: Journal article
C2 - 34081013
VL - 9
SP - e20407
JO - JMIR MED INF
JF - JMIR MED INF
SN - 2291-9694
IS - 6
M1 - e20407
ER -