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The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures

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The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures. / Meyer, Christian P; Rios-Diaz, Arturo J; Dalela, Deepansh; Ravi, Praful; Sood, Akshay; Hanske, Julian; Chun, Felix K H; Kibel, Adam S; Lipsitz, Stuart R; Sun, Maxine; Trinh, Quoc-Dien.

In: AM J SURG, Vol. 214, No. 5, 11.2017, p. 871-883.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Meyer, CP, Rios-Diaz, AJ, Dalela, D, Ravi, P, Sood, A, Hanske, J, Chun, FKH, Kibel, AS, Lipsitz, SR, Sun, M & Trinh, Q-D 2017, 'The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures', AM J SURG, vol. 214, no. 5, pp. 871-883. https://doi.org/10.1016/j.amjsurg.2016.11.023

APA

Meyer, C. P., Rios-Diaz, A. J., Dalela, D., Ravi, P., Sood, A., Hanske, J., Chun, F. K. H., Kibel, A. S., Lipsitz, S. R., Sun, M., & Trinh, Q-D. (2017). The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures. AM J SURG, 214(5), 871-883. https://doi.org/10.1016/j.amjsurg.2016.11.023

Vancouver

Meyer CP, Rios-Diaz AJ, Dalela D, Ravi P, Sood A, Hanske J et al. The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures. AM J SURG. 2017 Nov;214(5):871-883. https://doi.org/10.1016/j.amjsurg.2016.11.023

Bibtex

@article{a8db2bd3082a4b8f996f5ebb9aeda64b,
title = "The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures",
abstract = "BACKGROUND: Poor nutritional status is thought to influence peri- and postoperative outcomes. We assessed the association of hypoalbuminemia, a surrogate for poor nutritional status, with perioperative outcomes in patients undergoing one of 16 major surgical procedures.METHODS: Patients undergoing one of 16 major surgeries were identified using the ACS-NSQIP (2005-2011). Risk-adjusted logistic regression models examined the association of hypoalbuminemia on perioperative outcomes.RESULTS: Overall, 204,819 complete cases were identified, of whom 25.4% underwent major cardiovascular, 19.0% orthopedic and 55.6% oncologic surgery. Patients with hypoalbuminemia had significantly higher rates of complications, reoperations, readmissions, prolonged length-of-stay and mortality (all p < 0.001). After adjustment, hypoalbuminemia was an independent predictor of overall complications in 12 of the procedures examined and 30-day mortality in 11 of the procedures. Individual perioperative complication profile varied widely among procedures.CONCLUSIONS: Hypoalbuminemia exerts significant impact on perioperative outcomes. Its effect is procedure-specific and thus warrants targeted management strategies to improve surgical outcomes. In the absence of clear recommendations, our findings invite surgeons to assess preoperative albumin levels and to manage nutritional status accordingly.",
keywords = "Aged, Female, Humans, Hypoalbuminemia, Male, Middle Aged, Postoperative Complications, Prospective Studies, Surgical Procedures, Operative, Treatment Outcome, Journal Article",
author = "Meyer, {Christian P} and Rios-Diaz, {Arturo J} and Deepansh Dalela and Praful Ravi and Akshay Sood and Julian Hanske and Chun, {Felix K H} and Kibel, {Adam S} and Lipsitz, {Stuart R} and Maxine Sun and Quoc-Dien Trinh",
note = "Copyright {\textcopyright} 2016 Elsevier Inc. All rights reserved.",
year = "2017",
month = nov,
doi = "10.1016/j.amjsurg.2016.11.023",
language = "English",
volume = "214",
pages = "871--883",
journal = "AM J SURG",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "5",

}

RIS

TY - JOUR

T1 - The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures

AU - Meyer, Christian P

AU - Rios-Diaz, Arturo J

AU - Dalela, Deepansh

AU - Ravi, Praful

AU - Sood, Akshay

AU - Hanske, Julian

AU - Chun, Felix K H

AU - Kibel, Adam S

AU - Lipsitz, Stuart R

AU - Sun, Maxine

AU - Trinh, Quoc-Dien

N1 - Copyright © 2016 Elsevier Inc. All rights reserved.

PY - 2017/11

Y1 - 2017/11

N2 - BACKGROUND: Poor nutritional status is thought to influence peri- and postoperative outcomes. We assessed the association of hypoalbuminemia, a surrogate for poor nutritional status, with perioperative outcomes in patients undergoing one of 16 major surgical procedures.METHODS: Patients undergoing one of 16 major surgeries were identified using the ACS-NSQIP (2005-2011). Risk-adjusted logistic regression models examined the association of hypoalbuminemia on perioperative outcomes.RESULTS: Overall, 204,819 complete cases were identified, of whom 25.4% underwent major cardiovascular, 19.0% orthopedic and 55.6% oncologic surgery. Patients with hypoalbuminemia had significantly higher rates of complications, reoperations, readmissions, prolonged length-of-stay and mortality (all p < 0.001). After adjustment, hypoalbuminemia was an independent predictor of overall complications in 12 of the procedures examined and 30-day mortality in 11 of the procedures. Individual perioperative complication profile varied widely among procedures.CONCLUSIONS: Hypoalbuminemia exerts significant impact on perioperative outcomes. Its effect is procedure-specific and thus warrants targeted management strategies to improve surgical outcomes. In the absence of clear recommendations, our findings invite surgeons to assess preoperative albumin levels and to manage nutritional status accordingly.

AB - BACKGROUND: Poor nutritional status is thought to influence peri- and postoperative outcomes. We assessed the association of hypoalbuminemia, a surrogate for poor nutritional status, with perioperative outcomes in patients undergoing one of 16 major surgical procedures.METHODS: Patients undergoing one of 16 major surgeries were identified using the ACS-NSQIP (2005-2011). Risk-adjusted logistic regression models examined the association of hypoalbuminemia on perioperative outcomes.RESULTS: Overall, 204,819 complete cases were identified, of whom 25.4% underwent major cardiovascular, 19.0% orthopedic and 55.6% oncologic surgery. Patients with hypoalbuminemia had significantly higher rates of complications, reoperations, readmissions, prolonged length-of-stay and mortality (all p < 0.001). After adjustment, hypoalbuminemia was an independent predictor of overall complications in 12 of the procedures examined and 30-day mortality in 11 of the procedures. Individual perioperative complication profile varied widely among procedures.CONCLUSIONS: Hypoalbuminemia exerts significant impact on perioperative outcomes. Its effect is procedure-specific and thus warrants targeted management strategies to improve surgical outcomes. In the absence of clear recommendations, our findings invite surgeons to assess preoperative albumin levels and to manage nutritional status accordingly.

KW - Aged

KW - Female

KW - Humans

KW - Hypoalbuminemia

KW - Male

KW - Middle Aged

KW - Postoperative Complications

KW - Prospective Studies

KW - Surgical Procedures, Operative

KW - Treatment Outcome

KW - Journal Article

U2 - 10.1016/j.amjsurg.2016.11.023

DO - 10.1016/j.amjsurg.2016.11.023

M3 - SCORING: Journal article

C2 - 29106849

VL - 214

SP - 871

EP - 883

JO - AM J SURG

JF - AM J SURG

SN - 0002-9610

IS - 5

ER -