The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact

TY - JOUR

T1 - The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact

AU - Kalaria, Raj

AU - Maestre, Gladys

AU - Mahinrad, Simin

AU - Acosta, Daisy M

AU - Akinyemi, Rufus Olusola

AU - Alladi, Suvarna

AU - Allegri, Ricardo F

AU - Arshad, Faheem

AU - Babalola, David Oluwasayo

AU - Baiyewu, Olusegun

AU - Bak, Thomas H

AU - Bellaj, Tarek

AU - Brodie-Mends, David K

AU - Carrillo, Maria C

AU - Celestin, Kaputu-Kalala-Malu

AU - Damasceno, Albertino

AU - de Silva, Ranil Karunamuni

AU - de Silva, Rohan

AU - Djibuti, Mamuka

AU - Dreyer, Anna Jane

AU - Ellajosyula, Ratnavalli

AU - Farombi, Temitope H

AU - Friedland, Robert P

AU - Garza, Noe

AU - Gbessemehlan, Antoine

AU - Georgiou, Eliza Eleni-Zacharoula

AU - Govia, Ishtar

AU - Grinberg, Lea T

AU - Guerchet, Maëlenn

AU - Gugssa, Seid Ali

AU - Gumikiriza-Onoria, Joy Louise

AU - Hogervorst, Eef

AU - Hornberger, Michael

AU - Ibanez, Agustin

AU - Ihara, Masafumi

AU - Issac, Thomas Gregor

AU - Jönsson, Linus

AU - Karanja, Wambui M

AU - Lee, Joseph H

AU - Leroi, Iracema

AU - Livingston, Gill

AU - Manes, Facundo Francisco

AU - Mbakile-Mahlanza, Lingani

AU - Miller, Bruce L

AU - Musyimi, Christine Wayua

AU - Mutiso, Victoria N

AU - Nakasujja, Noeline

AU - Ndetei, David M

AU - Nightingale, Sam

AU - Novotni, Gabriela

AU - Nyamayaro, Primrose

AU - Nyame, Solomon

AU - Ogeng'o, Julius A

AU - Ogunniyi, Adesola

AU - de Oliveira, Maira Okada

AU - Okubadejo, Njideka U

AU - Orrell, Martin

AU - Paddick, Stella-Maria

AU - Pericak-Vance, Margaret A

AU - Pirtosek, Zvezdan

AU - Potocnik, Felix Claude Victor

AU - Raman, Rema

AU - Rizig, Mie

AU - Rosselli, Mónica

AU - Salokhiddinov, Marufjon

AU - Satizabal, Claudia L

AU - Sepulveda-Falla, Diego

AU - Seshadri, Sudha

AU - Sexton, Claire E

AU - Skoog, Ingmar

AU - George-Hyslop, Peter H St

AU - Suemoto, Claudia Kimie

AU - Thapa, Prekshy

AU - Udeh-Momoh, Chinedu Theresa

AU - Valcour, Victor

AU - Vance, Jeffery M

AU - Varghese, Mathew

AU - Vera, Jaime H

AU - Walker, Richard W

AU - Zetterberg, Henrik

AU - Zewde, Yared Z

AU - Ismail, Ozama

N1 - © 2024 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.

PY - 2024/6

Y1 - 2024/6

N2 - Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations. Development of effective preventive, diagnostic, and therapeutic approaches for dementia in LMICs requires targeted, personalized, and harmonized efforts. Our article represents timely discussions at the 2022 Symposium on Dementia and Brain Aging in LMICs that identified the foremost opportunities to advance dementia research, differential diagnosis, use of neuropsychometric tools, awareness, and treatment options. We highlight key topics discussed at the meeting and provide future recommendations to foster a more equitable landscape for dementia prevention, diagnosis, care, policy, and management in LMICs. HIGHLIGHTS: Two-thirds of persons with dementia live in LMICs, yet research and costs are skewed toward HICs. LMICs expect dementia prevalence to more than double, accompanied by socioeconomic disparities. The 2022 Symposium on Dementia in LMICs addressed advances in research, diagnosis, prevention, and policy. The Nairobi Declaration urges global action to enhance dementia outcomes in LMICs.

AB - Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations. Development of effective preventive, diagnostic, and therapeutic approaches for dementia in LMICs requires targeted, personalized, and harmonized efforts. Our article represents timely discussions at the 2022 Symposium on Dementia and Brain Aging in LMICs that identified the foremost opportunities to advance dementia research, differential diagnosis, use of neuropsychometric tools, awareness, and treatment options. We highlight key topics discussed at the meeting and provide future recommendations to foster a more equitable landscape for dementia prevention, diagnosis, care, policy, and management in LMICs. HIGHLIGHTS: Two-thirds of persons with dementia live in LMICs, yet research and costs are skewed toward HICs. LMICs expect dementia prevalence to more than double, accompanied by socioeconomic disparities. The 2022 Symposium on Dementia in LMICs addressed advances in research, diagnosis, prevention, and policy. The Nairobi Declaration urges global action to enhance dementia outcomes in LMICs.

U2 - 10.1002/alz.13836

DO - 10.1002/alz.13836

M3 - SCORING: Review article

C2 - 38696263

VL - 20

SP - 4290

EP - 4314

JO - ALZHEIMERS DEMENT

JF - ALZHEIMERS DEMENT

SN - 1552-5260

IS - 6

ER -