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Temporal trends in incidence and outcome of acute coronary syndrome

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Temporal trends in incidence and outcome of acute coronary syndrome. / Neumann, Johannes T; Goßling, Alina; Sörensen, Nils A; Blankenberg, Stefan; Magnussen, Christina; Westermann, Dirk.

In: CLIN RES CARDIOL, Vol. 109, No. 9, 09.2020, p. 1186-1192.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Neumann, JT, Goßling, A, Sörensen, NA, Blankenberg, S, Magnussen, C & Westermann, D 2020, 'Temporal trends in incidence and outcome of acute coronary syndrome', CLIN RES CARDIOL, vol. 109, no. 9, pp. 1186-1192. https://doi.org/10.1007/s00392-020-01612-1

APA

Neumann, J. T., Goßling, A., Sörensen, N. A., Blankenberg, S., Magnussen, C., & Westermann, D. (2020). Temporal trends in incidence and outcome of acute coronary syndrome. CLIN RES CARDIOL, 109(9), 1186-1192. https://doi.org/10.1007/s00392-020-01612-1

Vancouver

Neumann JT, Goßling A, Sörensen NA, Blankenberg S, Magnussen C, Westermann D. Temporal trends in incidence and outcome of acute coronary syndrome. CLIN RES CARDIOL. 2020 Sep;109(9):1186-1192. https://doi.org/10.1007/s00392-020-01612-1

Bibtex

@article{1a5612c73e9845bdaba65ee420aea358,
title = "Temporal trends in incidence and outcome of acute coronary syndrome",
abstract = "BACKGROUND: We aimed to investigate changes of incidence, outcome and related interventions of patients with acute coronary syndrome (ACS) over the past decade in Germany.METHODS: Data on the international statistical classification of diseases and procedural codes from the Federal Bureau of Statistics in Germany was used. This included all ACS cases in Germany in the years 2005-2015. Analyses were performed separately for the diagnoses of overall ACS, ST-elevation myocardial infarction (MI), non-ST-elevation MI and unstable angina pectoris. Procedures including coronary angiography and percutaneous coronary intervention and the endpoint in-hospital mortality were assessed.RESULTS: Between 2005 and 2015 a total of 3797,546 cases of ACS were recorded. The mean age was 69 years and 36% were females. In-hospital mortality was 6.3%, 62% underwent coronary angiography and 42% received percutaneous coronary intervention. In-hospital mortality was highest for patients with ST-elevation MI (12.0%) and lowest for patients with unstable angina pectoris (0.6%). From 2005 to 2015 the incidence rates of ACS, ST-elevation MI and unstable angina pectoris decreased, while the incidence rate of non-ST-elevation MI increased. The percentages of performed coronary angiographies and percutaneous coronary interventions increased from 52 to 70% and 34 to 50%, respectively. The adjusted incidence rate of in-hospital mortality decreased from 64.9 cases per 1000 person-years to 54.8 cases.CONCLUSION: In a large dataset including more than 3.7 million cases, we report an increase in coronary procedures and a reduction of ACS incidence and related mortality in the past decade in Germany.",
keywords = "Acute Coronary Syndrome/epidemiology, Aged, Aged, 80 and over, Angina, Unstable/epidemiology, Coronary Angiography/trends, Female, Germany/epidemiology, Hospital Mortality/trends, Humans, Incidence, Male, Middle Aged, Non-ST Elevated Myocardial Infarction/epidemiology, Percutaneous Coronary Intervention/trends, ST Elevation Myocardial Infarction/epidemiology",
author = "Neumann, {Johannes T} and Alina Go{\ss}ling and S{\"o}rensen, {Nils A} and Stefan Blankenberg and Christina Magnussen and Dirk Westermann",
year = "2020",
month = sep,
doi = "10.1007/s00392-020-01612-1",
language = "English",
volume = "109",
pages = "1186--1192",
journal = "CLIN RES CARDIOL",
issn = "1861-0684",
publisher = "D. Steinkopff-Verlag",
number = "9",

}

RIS

TY - JOUR

T1 - Temporal trends in incidence and outcome of acute coronary syndrome

AU - Neumann, Johannes T

AU - Goßling, Alina

AU - Sörensen, Nils A

AU - Blankenberg, Stefan

AU - Magnussen, Christina

AU - Westermann, Dirk

PY - 2020/9

Y1 - 2020/9

N2 - BACKGROUND: We aimed to investigate changes of incidence, outcome and related interventions of patients with acute coronary syndrome (ACS) over the past decade in Germany.METHODS: Data on the international statistical classification of diseases and procedural codes from the Federal Bureau of Statistics in Germany was used. This included all ACS cases in Germany in the years 2005-2015. Analyses were performed separately for the diagnoses of overall ACS, ST-elevation myocardial infarction (MI), non-ST-elevation MI and unstable angina pectoris. Procedures including coronary angiography and percutaneous coronary intervention and the endpoint in-hospital mortality were assessed.RESULTS: Between 2005 and 2015 a total of 3797,546 cases of ACS were recorded. The mean age was 69 years and 36% were females. In-hospital mortality was 6.3%, 62% underwent coronary angiography and 42% received percutaneous coronary intervention. In-hospital mortality was highest for patients with ST-elevation MI (12.0%) and lowest for patients with unstable angina pectoris (0.6%). From 2005 to 2015 the incidence rates of ACS, ST-elevation MI and unstable angina pectoris decreased, while the incidence rate of non-ST-elevation MI increased. The percentages of performed coronary angiographies and percutaneous coronary interventions increased from 52 to 70% and 34 to 50%, respectively. The adjusted incidence rate of in-hospital mortality decreased from 64.9 cases per 1000 person-years to 54.8 cases.CONCLUSION: In a large dataset including more than 3.7 million cases, we report an increase in coronary procedures and a reduction of ACS incidence and related mortality in the past decade in Germany.

AB - BACKGROUND: We aimed to investigate changes of incidence, outcome and related interventions of patients with acute coronary syndrome (ACS) over the past decade in Germany.METHODS: Data on the international statistical classification of diseases and procedural codes from the Federal Bureau of Statistics in Germany was used. This included all ACS cases in Germany in the years 2005-2015. Analyses were performed separately for the diagnoses of overall ACS, ST-elevation myocardial infarction (MI), non-ST-elevation MI and unstable angina pectoris. Procedures including coronary angiography and percutaneous coronary intervention and the endpoint in-hospital mortality were assessed.RESULTS: Between 2005 and 2015 a total of 3797,546 cases of ACS were recorded. The mean age was 69 years and 36% were females. In-hospital mortality was 6.3%, 62% underwent coronary angiography and 42% received percutaneous coronary intervention. In-hospital mortality was highest for patients with ST-elevation MI (12.0%) and lowest for patients with unstable angina pectoris (0.6%). From 2005 to 2015 the incidence rates of ACS, ST-elevation MI and unstable angina pectoris decreased, while the incidence rate of non-ST-elevation MI increased. The percentages of performed coronary angiographies and percutaneous coronary interventions increased from 52 to 70% and 34 to 50%, respectively. The adjusted incidence rate of in-hospital mortality decreased from 64.9 cases per 1000 person-years to 54.8 cases.CONCLUSION: In a large dataset including more than 3.7 million cases, we report an increase in coronary procedures and a reduction of ACS incidence and related mortality in the past decade in Germany.

KW - Acute Coronary Syndrome/epidemiology

KW - Aged

KW - Aged, 80 and over

KW - Angina, Unstable/epidemiology

KW - Coronary Angiography/trends

KW - Female

KW - Germany/epidemiology

KW - Hospital Mortality/trends

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Non-ST Elevated Myocardial Infarction/epidemiology

KW - Percutaneous Coronary Intervention/trends

KW - ST Elevation Myocardial Infarction/epidemiology

U2 - 10.1007/s00392-020-01612-1

DO - 10.1007/s00392-020-01612-1

M3 - SCORING: Journal article

C2 - 32034482

VL - 109

SP - 1186

EP - 1192

JO - CLIN RES CARDIOL

JF - CLIN RES CARDIOL

SN - 1861-0684

IS - 9

ER -