Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients: study design and description of the intervention

Friedrich Koehler; Kerstin Koehler; Oliver Deckwart; Sandra Prescher; Karl Wegscheider; Sebastian Winkler; Eik Vettorazzi; Andreas Polze; Karl Stangl; Oliver Hartmann; Almuth Marx; Petra Neuhaus; Michael Scherf; Bridget-Anne Kirwan; Stefan D Anker

doi:10.1002/ejhf.1300

Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients: study design and description of the intervention

Standard

Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients: study design and description of the intervention. / Koehler, Friedrich; Koehler, Kerstin; Deckwart, Oliver; Prescher, Sandra; Wegscheider, Karl; Winkler, Sebastian; Vettorazzi, Eik; Polze, Andreas; Stangl, Karl; Hartmann, Oliver; Marx, Almuth; Neuhaus, Petra; Scherf, Michael; Kirwan, Bridget-Anne; Anker, Stefan D.

In: EUR J HEART FAIL, Vol. 20, No. 10, 10.2018, p. 1485-1493.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Koehler, F, Koehler, K, Deckwart, O, Prescher, S, Wegscheider, K, Winkler, S, Vettorazzi, E, Polze, A, Stangl, K, Hartmann, O, Marx, A, Neuhaus, P, Scherf, M, Kirwan, B-A & Anker, SD 2018, 'Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients: study design and description of the intervention', EUR J HEART FAIL, vol. 20, no. 10, pp. 1485-1493. https://doi.org/10.1002/ejhf.1300

APA

Koehler, F., Koehler, K., Deckwart, O., Prescher, S., Wegscheider, K., Winkler, S., Vettorazzi, E., Polze, A., Stangl, K., Hartmann, O., Marx, A., Neuhaus, P., Scherf, M., Kirwan, B-A., & Anker, S. D. (2018). Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients: study design and description of the intervention. EUR J HEART FAIL, 20(10), 1485-1493. https://doi.org/10.1002/ejhf.1300

Vancouver

Koehler F, Koehler K, Deckwart O, Prescher S, Wegscheider K, Winkler S et al. Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients: study design and description of the intervention. EUR J HEART FAIL. 2018 Oct;20(10):1485-1493. https://doi.org/10.1002/ejhf.1300

Bibtex

@article{f30e0fe817b94633ba5b8477e2065f04,

title = "Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients: study design and description of the intervention",

abstract = "BACKGROUND: Heart failure (HF) is a complex, chronic condition that is associated with debilitating symptoms, all of which necessitate close follow-up by health care providers. Lack of disease monitoring may result in increased mortality and more frequent hospital readmissions for decompensated HF. Remote patient management (RPM) in this patient population may help to detect early signs and symptoms of cardiac decompensation, thus enabling a prompt initiation of the appropriate treatment and care before a manifestation of HF decompensation.OBJECTIVE: The objective of the present article is to describe the design of a new trial investigating the impact of RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.METHODS: The TIM-HF2 trial is designed as a prospective, randomised, controlled, parallel group, open (with randomisation concealment), multicentre trial with pragmatic elements introduced for data collection. Eligible patients with HF are randomised (1:1) to either RPM + usual care or to usual care only and are followed for 12 months. The primary outcome is the percentage of days lost due to unplanned cardiovascular hospitalisations or all-cause death. The main secondary outcomes are all-cause and cardiovascular mortality.CONCLUSION: The TIM-HF2 trial will provide important prospective data on the potential beneficial effect of telemedical monitoring and RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT01878630.",

keywords = "Journal Article",

author = "Friedrich Koehler and Kerstin Koehler and Oliver Deckwart and Sandra Prescher and Karl Wegscheider and Sebastian Winkler and Eik Vettorazzi and Andreas Polze and Karl Stangl and Oliver Hartmann and Almuth Marx and Petra Neuhaus and Michael Scherf and Bridget-Anne Kirwan and Anker, {Stefan D}",

note = "{\textcopyright} 2018 The Authors. European Journal of Heart Failure {\textcopyright} 2018 European Society of Cardiology.",

year = "2018",

month = oct,

doi = "10.1002/ejhf.1300",

language = "English",

volume = "20",

pages = "1485--1493",

journal = "EUR J HEART FAIL",

issn = "1388-9842",

publisher = "Oxford University Press",

number = "10",

}

RIS

TY - JOUR

T1 - Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients: study design and description of the intervention

AU - Koehler, Friedrich

AU - Koehler, Kerstin

AU - Deckwart, Oliver

AU - Prescher, Sandra

AU - Wegscheider, Karl

AU - Winkler, Sebastian

AU - Vettorazzi, Eik

AU - Polze, Andreas

AU - Stangl, Karl

AU - Hartmann, Oliver

AU - Marx, Almuth

AU - Neuhaus, Petra

AU - Scherf, Michael

AU - Kirwan, Bridget-Anne

AU - Anker, Stefan D

PY - 2018/10

Y1 - 2018/10

N2 - BACKGROUND: Heart failure (HF) is a complex, chronic condition that is associated with debilitating symptoms, all of which necessitate close follow-up by health care providers. Lack of disease monitoring may result in increased mortality and more frequent hospital readmissions for decompensated HF. Remote patient management (RPM) in this patient population may help to detect early signs and symptoms of cardiac decompensation, thus enabling a prompt initiation of the appropriate treatment and care before a manifestation of HF decompensation.OBJECTIVE: The objective of the present article is to describe the design of a new trial investigating the impact of RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.METHODS: The TIM-HF2 trial is designed as a prospective, randomised, controlled, parallel group, open (with randomisation concealment), multicentre trial with pragmatic elements introduced for data collection. Eligible patients with HF are randomised (1:1) to either RPM + usual care or to usual care only and are followed for 12 months. The primary outcome is the percentage of days lost due to unplanned cardiovascular hospitalisations or all-cause death. The main secondary outcomes are all-cause and cardiovascular mortality.CONCLUSION: The TIM-HF2 trial will provide important prospective data on the potential beneficial effect of telemedical monitoring and RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT01878630.

AB - BACKGROUND: Heart failure (HF) is a complex, chronic condition that is associated with debilitating symptoms, all of which necessitate close follow-up by health care providers. Lack of disease monitoring may result in increased mortality and more frequent hospital readmissions for decompensated HF. Remote patient management (RPM) in this patient population may help to detect early signs and symptoms of cardiac decompensation, thus enabling a prompt initiation of the appropriate treatment and care before a manifestation of HF decompensation.OBJECTIVE: The objective of the present article is to describe the design of a new trial investigating the impact of RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.METHODS: The TIM-HF2 trial is designed as a prospective, randomised, controlled, parallel group, open (with randomisation concealment), multicentre trial with pragmatic elements introduced for data collection. Eligible patients with HF are randomised (1:1) to either RPM + usual care or to usual care only and are followed for 12 months. The primary outcome is the percentage of days lost due to unplanned cardiovascular hospitalisations or all-cause death. The main secondary outcomes are all-cause and cardiovascular mortality.CONCLUSION: The TIM-HF2 trial will provide important prospective data on the potential beneficial effect of telemedical monitoring and RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT01878630.

KW - Journal Article

UR - https://telemedizin.charite.de/forschung/fontane/tim_hf2/

U2 - 10.1002/ejhf.1300

DO - 10.1002/ejhf.1300

M3 - SCORING: Journal article

C2 - 30230666

VL - 20

SP - 1485

EP - 1493

JO - EUR J HEART FAIL

JF - EUR J HEART FAIL

SN - 1388-9842

IS - 10

ER -