Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells.
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Abstract
The phosphoinositide 3-kinase (PI3K)/Akt pathway is frequently activated in human cancer and plays a crucial role in neuroblastoma biology. We were interested in gaining further insight into the potential of targeting PI3K/Akt signaling as a novel antiproliferative approach in neuroblastoma.
Bibliographical data
| Original language | German |
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| Article number | 4 |
| ISSN | 1078-0432 |
| Publication status | Published - 2008 |
| pubmed | 18281552 |
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