Tacrolimus and cyclosporine have differential effects on the risk of development of bronchiolitis obliterans syndrome: results of a prospective, randomized international trial in lung transplantation.

  • Hendrik Treede
  • Allan R Glanville
  • Walter Klepetko
  • Christina Aboyoun
  • Eik Vettorazzi
  • Raffael Lama
  • Carlos Bravo
  • Christiane Knoop
  • John-David Aubert
  • Hermann Reichenspurner
  • [Unbekannt] European
  • Australian Investigators In Lung Transplantation

Abstract

Chronic lung allograft dysfunction, which manifests as bronchiolitis obliterans syndrome (BOS), is recognized as the primary cause of morbidity and mortality after lung transplantation. In this study we assessed the efficacy and safety of two de novo immunosuppression protocols to prevent BOS.

Bibliographical data

Original languageEnglish
Article number8
ISSN1053-2498
Publication statusPublished - 2012
pubmed 22554673