Systemic treatment of vulvar cancer

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Systemic treatment of vulvar cancer. / Mahner, Sven; Prieske, Katharina; Grimm, Donata; Trillsch, Fabian; Prieske, Stefan; von Amsberg, Gunhild; Petersen, Cordula; Müller, Volkmar; Jänicke, Fritz; Woelber, Linn.

In: EXPERT REV ANTICANC, Vol. 15, No. 6, 06.2015, p. 629-37.

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@article{d309920387e8452fb5a52f9c510917bb,
title = "Systemic treatment of vulvar cancer",
abstract = "Squamous cell carcinoma of the vulva is a rare disease, accounting for approximately 5% of cancers of the female genital tract. Standard therapy for early-stage vulvar cancer mainly comprises of surgery of the vulva and groins. In locally advanced or metastatic vulvar cancer, neoadjuvant or definitive chemoradiation is often considered as an alternative treatment option. Given its rarity, the level of evidence for different treatment modalities is poor and few clinical trials have been performed on this disease. Therefore indication criteria for systemic treatment in advanced stage vulvar cancer vary widely among countries and institutions. This review focuses on the different systemic treatment options for patients with locally advanced, recurrent or metastatic vulvar cancer, and highlights the need for an international multicenter approach to identify the most effective therapeutic options.",
author = "Sven Mahner and Katharina Prieske and Donata Grimm and Fabian Trillsch and Stefan Prieske and {von Amsberg}, Gunhild and Cordula Petersen and Volkmar M{\"u}ller and Fritz J{\"a}nicke and Linn Woelber",
year = "2015",
month = jun,
doi = "10.1586/14737140.2015.1037837",
language = "English",
volume = "15",
pages = "629--37",
journal = "EXPERT REV ANTICANC",
issn = "1473-7140",
publisher = "Expert Reviews Ltd.",
number = "6",

}

RIS

TY - JOUR

T1 - Systemic treatment of vulvar cancer

AU - Mahner, Sven

AU - Prieske, Katharina

AU - Grimm, Donata

AU - Trillsch, Fabian

AU - Prieske, Stefan

AU - von Amsberg, Gunhild

AU - Petersen, Cordula

AU - Müller, Volkmar

AU - Jänicke, Fritz

AU - Woelber, Linn

PY - 2015/6

Y1 - 2015/6

N2 - Squamous cell carcinoma of the vulva is a rare disease, accounting for approximately 5% of cancers of the female genital tract. Standard therapy for early-stage vulvar cancer mainly comprises of surgery of the vulva and groins. In locally advanced or metastatic vulvar cancer, neoadjuvant or definitive chemoradiation is often considered as an alternative treatment option. Given its rarity, the level of evidence for different treatment modalities is poor and few clinical trials have been performed on this disease. Therefore indication criteria for systemic treatment in advanced stage vulvar cancer vary widely among countries and institutions. This review focuses on the different systemic treatment options for patients with locally advanced, recurrent or metastatic vulvar cancer, and highlights the need for an international multicenter approach to identify the most effective therapeutic options.

AB - Squamous cell carcinoma of the vulva is a rare disease, accounting for approximately 5% of cancers of the female genital tract. Standard therapy for early-stage vulvar cancer mainly comprises of surgery of the vulva and groins. In locally advanced or metastatic vulvar cancer, neoadjuvant or definitive chemoradiation is often considered as an alternative treatment option. Given its rarity, the level of evidence for different treatment modalities is poor and few clinical trials have been performed on this disease. Therefore indication criteria for systemic treatment in advanced stage vulvar cancer vary widely among countries and institutions. This review focuses on the different systemic treatment options for patients with locally advanced, recurrent or metastatic vulvar cancer, and highlights the need for an international multicenter approach to identify the most effective therapeutic options.

U2 - 10.1586/14737140.2015.1037837

DO - 10.1586/14737140.2015.1037837

M3 - SCORING: Journal article

C2 - 25997120

VL - 15

SP - 629

EP - 637

JO - EXPERT REV ANTICANC

JF - EXPERT REV ANTICANC

SN - 1473-7140

IS - 6

ER -