Subtotal and total resection of superficial plexiform neurofibromas of face and neck
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Subtotal and total resection of superficial plexiform neurofibromas of face and neck : four case reports. / Friedrich, Reinhard E; Schmelzle, Rainer; Hartmann, Melanie; Mautner, Victor-F.
In: J CRANIO MAXILL SURG, Vol. 33, No. 1, 01.02.2005, p. 55-60.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Subtotal and total resection of superficial plexiform neurofibromas of face and neck
T2 - four case reports
AU - Friedrich, Reinhard E
AU - Schmelzle, Rainer
AU - Hartmann, Melanie
AU - Mautner, Victor-F
PY - 2005/2/1
Y1 - 2005/2/1
N2 - INTRODUCTION: Plexiform neurofibromas are benign tumours of the peripheral nerves and connective tissue. They develop most often in patients with neurofibromatosis type 1 (NF1) and often grow continuously. Removal of plexiform neurofibromas is usually unsatisfactory because the network-like growth of these tumours often involves multiple nerve fascicles and other adjacent tissues. It has been previously shown that magnetic resonance tomography can distinguish the growth patterns of plexiform neurofibromas into three different categories: superficial, displacing and invasive.PATIENTS AND METHODS: Three cases are described with successful subtotal resections of superficial plexiform neurofibromas, and one case with total resection following the diagnosis of tumour subtype using magnetic resonance imaging (MRI).RESULTS: There was a significant, lasting improvement in appearance which demonstrates that surgical intervention in the case of superficial plexiform neurofibroma is valuable.CONCLUSION: Careful classification of plexiform neurofibroma by means of MRI provides valuable information for the surgical management of patients. It enables the distinction to be drawn between this subtype and the other two subtypes of plexiform neurofibromas.
AB - INTRODUCTION: Plexiform neurofibromas are benign tumours of the peripheral nerves and connective tissue. They develop most often in patients with neurofibromatosis type 1 (NF1) and often grow continuously. Removal of plexiform neurofibromas is usually unsatisfactory because the network-like growth of these tumours often involves multiple nerve fascicles and other adjacent tissues. It has been previously shown that magnetic resonance tomography can distinguish the growth patterns of plexiform neurofibromas into three different categories: superficial, displacing and invasive.PATIENTS AND METHODS: Three cases are described with successful subtotal resections of superficial plexiform neurofibromas, and one case with total resection following the diagnosis of tumour subtype using magnetic resonance imaging (MRI).RESULTS: There was a significant, lasting improvement in appearance which demonstrates that surgical intervention in the case of superficial plexiform neurofibroma is valuable.CONCLUSION: Careful classification of plexiform neurofibroma by means of MRI provides valuable information for the surgical management of patients. It enables the distinction to be drawn between this subtype and the other two subtypes of plexiform neurofibromas.
KW - Adolescent
KW - Adult
KW - Aged
KW - Head and Neck Neoplasms
KW - Humans
KW - Magnetic Resonance Imaging
KW - Male
KW - Middle Aged
KW - Neurofibroma, Plexiform
KW - Retreatment
U2 - 10.1016/j.jcms.2004.08.004
DO - 10.1016/j.jcms.2004.08.004
M3 - SCORING: Journal article
C2 - 15694151
VL - 33
SP - 55
EP - 60
JO - J CRANIO MAXILL SURG
JF - J CRANIO MAXILL SURG
SN - 1010-5182
IS - 1
ER -