Subtotal and total resection of superficial plexiform neurofibromas of face and neck

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Subtotal and total resection of superficial plexiform neurofibromas of face and neck : four case reports. / Friedrich, Reinhard E; Schmelzle, Rainer; Hartmann, Melanie; Mautner, Victor-F.

In: J CRANIO MAXILL SURG, Vol. 33, No. 1, 01.02.2005, p. 55-60.

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@article{791f5e630bb645e9862923db8b976634,
title = "Subtotal and total resection of superficial plexiform neurofibromas of face and neck: four case reports",
abstract = "INTRODUCTION: Plexiform neurofibromas are benign tumours of the peripheral nerves and connective tissue. They develop most often in patients with neurofibromatosis type 1 (NF1) and often grow continuously. Removal of plexiform neurofibromas is usually unsatisfactory because the network-like growth of these tumours often involves multiple nerve fascicles and other adjacent tissues. It has been previously shown that magnetic resonance tomography can distinguish the growth patterns of plexiform neurofibromas into three different categories: superficial, displacing and invasive.PATIENTS AND METHODS: Three cases are described with successful subtotal resections of superficial plexiform neurofibromas, and one case with total resection following the diagnosis of tumour subtype using magnetic resonance imaging (MRI).RESULTS: There was a significant, lasting improvement in appearance which demonstrates that surgical intervention in the case of superficial plexiform neurofibroma is valuable.CONCLUSION: Careful classification of plexiform neurofibroma by means of MRI provides valuable information for the surgical management of patients. It enables the distinction to be drawn between this subtype and the other two subtypes of plexiform neurofibromas.",
keywords = "Adolescent, Adult, Aged, Head and Neck Neoplasms, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neurofibroma, Plexiform, Retreatment",
author = "Friedrich, {Reinhard E} and Rainer Schmelzle and Melanie Hartmann and Victor-F Mautner",
year = "2005",
month = feb,
day = "1",
doi = "10.1016/j.jcms.2004.08.004",
language = "English",
volume = "33",
pages = "55--60",
journal = "J CRANIO MAXILL SURG",
issn = "1010-5182",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Subtotal and total resection of superficial plexiform neurofibromas of face and neck

T2 - four case reports

AU - Friedrich, Reinhard E

AU - Schmelzle, Rainer

AU - Hartmann, Melanie

AU - Mautner, Victor-F

PY - 2005/2/1

Y1 - 2005/2/1

N2 - INTRODUCTION: Plexiform neurofibromas are benign tumours of the peripheral nerves and connective tissue. They develop most often in patients with neurofibromatosis type 1 (NF1) and often grow continuously. Removal of plexiform neurofibromas is usually unsatisfactory because the network-like growth of these tumours often involves multiple nerve fascicles and other adjacent tissues. It has been previously shown that magnetic resonance tomography can distinguish the growth patterns of plexiform neurofibromas into three different categories: superficial, displacing and invasive.PATIENTS AND METHODS: Three cases are described with successful subtotal resections of superficial plexiform neurofibromas, and one case with total resection following the diagnosis of tumour subtype using magnetic resonance imaging (MRI).RESULTS: There was a significant, lasting improvement in appearance which demonstrates that surgical intervention in the case of superficial plexiform neurofibroma is valuable.CONCLUSION: Careful classification of plexiform neurofibroma by means of MRI provides valuable information for the surgical management of patients. It enables the distinction to be drawn between this subtype and the other two subtypes of plexiform neurofibromas.

AB - INTRODUCTION: Plexiform neurofibromas are benign tumours of the peripheral nerves and connective tissue. They develop most often in patients with neurofibromatosis type 1 (NF1) and often grow continuously. Removal of plexiform neurofibromas is usually unsatisfactory because the network-like growth of these tumours often involves multiple nerve fascicles and other adjacent tissues. It has been previously shown that magnetic resonance tomography can distinguish the growth patterns of plexiform neurofibromas into three different categories: superficial, displacing and invasive.PATIENTS AND METHODS: Three cases are described with successful subtotal resections of superficial plexiform neurofibromas, and one case with total resection following the diagnosis of tumour subtype using magnetic resonance imaging (MRI).RESULTS: There was a significant, lasting improvement in appearance which demonstrates that surgical intervention in the case of superficial plexiform neurofibroma is valuable.CONCLUSION: Careful classification of plexiform neurofibroma by means of MRI provides valuable information for the surgical management of patients. It enables the distinction to be drawn between this subtype and the other two subtypes of plexiform neurofibromas.

KW - Adolescent

KW - Adult

KW - Aged

KW - Head and Neck Neoplasms

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Middle Aged

KW - Neurofibroma, Plexiform

KW - Retreatment

U2 - 10.1016/j.jcms.2004.08.004

DO - 10.1016/j.jcms.2004.08.004

M3 - SCORING: Journal article

C2 - 15694151

VL - 33

SP - 55

EP - 60

JO - J CRANIO MAXILL SURG

JF - J CRANIO MAXILL SURG

SN - 1010-5182

IS - 1

ER -