Subthalamotomy in cervical dystonia

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Subthalamotomy in cervical dystonia : A case study of lesion location and clinical outcome. / Moll, Christian K E; Hamel, Wolfgang; Ostertag, Christoph B; Müller, Dieter; Finsterbusch, Jürgen; Engel, Andreas K; Münchau, Alexander.

In: MOVEMENT DISORD, Vol. 23, No. 12, 15.09.2008, p. 1751-6.

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@article{f03cc0baf3a14f7bb592a28f0185f07d,
title = "Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome",
abstract = "Here we report a 63-year-old woman with primary cervical dystonia (CD) whose symptoms subsided for more than 30 years following a unilateral stereotactic subthalamotomy contralateral to the overactive left sternocleidomastoid muscle but then gradually recurred over a period of several months. The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High-resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation.",
keywords = "Female, Humans, Magnetic Resonance Imaging, Middle Aged, Neurologic Examination, Postoperative Period, Subthalamus, Torticollis",
author = "Moll, {Christian K E} and Wolfgang Hamel and Ostertag, {Christoph B} and Dieter M{\"u}ller and J{\"u}rgen Finsterbusch and Engel, {Andreas K} and Alexander M{\"u}nchau",
note = "(c) 2007 Movement Disorder Society.",
year = "2008",
month = sep,
day = "15",
doi = "10.1002/mds.22088",
language = "English",
volume = "23",
pages = "1751--6",
journal = "MOVEMENT DISORD",
issn = "0885-3185",
publisher = "John Wiley and Sons Inc.",
number = "12",

}

RIS

TY - JOUR

T1 - Subthalamotomy in cervical dystonia

T2 - A case study of lesion location and clinical outcome

AU - Moll, Christian K E

AU - Hamel, Wolfgang

AU - Ostertag, Christoph B

AU - Müller, Dieter

AU - Finsterbusch, Jürgen

AU - Engel, Andreas K

AU - Münchau, Alexander

N1 - (c) 2007 Movement Disorder Society.

PY - 2008/9/15

Y1 - 2008/9/15

N2 - Here we report a 63-year-old woman with primary cervical dystonia (CD) whose symptoms subsided for more than 30 years following a unilateral stereotactic subthalamotomy contralateral to the overactive left sternocleidomastoid muscle but then gradually recurred over a period of several months. The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High-resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation.

AB - Here we report a 63-year-old woman with primary cervical dystonia (CD) whose symptoms subsided for more than 30 years following a unilateral stereotactic subthalamotomy contralateral to the overactive left sternocleidomastoid muscle but then gradually recurred over a period of several months. The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High-resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation.

KW - Female

KW - Humans

KW - Magnetic Resonance Imaging

KW - Middle Aged

KW - Neurologic Examination

KW - Postoperative Period

KW - Subthalamus

KW - Torticollis

U2 - 10.1002/mds.22088

DO - 10.1002/mds.22088

M3 - SCORING: Journal article

C2 - 18709687

VL - 23

SP - 1751

EP - 1756

JO - MOVEMENT DISORD

JF - MOVEMENT DISORD

SN - 0885-3185

IS - 12

ER -