Structural and functional heterogeneity of naturally occurring hepatitis B virus variants.
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Structural and functional heterogeneity of naturally occurring hepatitis B virus variants. / Burda, M R; Günther, S; Dandri-Petersen, Maura; Will, H; Petersen, J.
In: ANTIVIR RES, Vol. 52, No. 2, 2, 2001, p. 125-138.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Structural and functional heterogeneity of naturally occurring hepatitis B virus variants.
AU - Burda, M R
AU - Günther, S
AU - Dandri-Petersen, Maura
AU - Will, H
AU - Petersen, J
PY - 2001
Y1 - 2001
N2 - Most organisms have developed sophisticated machineries to preserve their genomic integrity. On the contrary hepatitis B virus (HBV), like a lot of other viruses can undergo rapid and drastic sequence changes, especially if the virus has to cope with natural or therapy induced antiviral mechanisms in the host. Here, we try to summarize possible implications for the molecular pathogenesis of HBV based on the extensive research on the genetic variants of HBV.
AB - Most organisms have developed sophisticated machineries to preserve their genomic integrity. On the contrary hepatitis B virus (HBV), like a lot of other viruses can undergo rapid and drastic sequence changes, especially if the virus has to cope with natural or therapy induced antiviral mechanisms in the host. Here, we try to summarize possible implications for the molecular pathogenesis of HBV based on the extensive research on the genetic variants of HBV.
M3 - SCORING: Zeitschriftenaufsatz
VL - 52
SP - 125
EP - 138
IS - 2
M1 - 2
ER -
