Stroke-like pattern in DTI and MRS of childhood mitochondrial leukoencephalopathy.
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Stroke-like pattern in DTI and MRS of childhood mitochondrial leukoencephalopathy. / Brockmann, K; Finsterbusch, Jürgen; Schara, U; Wilichowski, E; Frahm, J; Hanefeld, F.
In: NEURORADIOLOGY, Vol. 46, No. 4, 4, 2004, p. 267-271.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Stroke-like pattern in DTI and MRS of childhood mitochondrial leukoencephalopathy.
AU - Brockmann, K
AU - Finsterbusch, Jürgen
AU - Schara, U
AU - Wilichowski, E
AU - Frahm, J
AU - Hanefeld, F
PY - 2004
Y1 - 2004
N2 - In a 13-month-old boy with recurrent motor deterioration provoked by fever MRI and proton MRS detected a leukoencephalopathy with reduced cerebral metabolites and elevated lactate. At follow-up 6 and 16 months later these abnormalities improved gradually. Serial diffusion tensor imaging revealed a stroke-like pattern with an initial strong reduction of the apparent diffusion coefficient followed by elevated values 6 months later. The relative diffusion anisotropy remained reduced. Muscle biopsy confirmed a mitochondrial encephalomyopathy.
AB - In a 13-month-old boy with recurrent motor deterioration provoked by fever MRI and proton MRS detected a leukoencephalopathy with reduced cerebral metabolites and elevated lactate. At follow-up 6 and 16 months later these abnormalities improved gradually. Serial diffusion tensor imaging revealed a stroke-like pattern with an initial strong reduction of the apparent diffusion coefficient followed by elevated values 6 months later. The relative diffusion anisotropy remained reduced. Muscle biopsy confirmed a mitochondrial encephalomyopathy.
M3 - SCORING: Zeitschriftenaufsatz
VL - 46
SP - 267
EP - 271
JO - NEURORADIOLOGY
JF - NEURORADIOLOGY
SN - 0028-3940
IS - 4
M1 - 4
ER -
