Stellate ganglionitis in sudden cardiac death
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Stellate ganglionitis in sudden cardiac death. / Duffy, Michael; Garland, Jack; Ondruschka, Benjamin; Paton, Julian F R; Bardsley, Emma N; Wong, Christopher X; Stables, Simon; Tse, Rexson.
In: AUTON NEUROSCI-BASIC, Vol. 234, 102837, 09.2021.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Stellate ganglionitis in sudden cardiac death
AU - Duffy, Michael
AU - Garland, Jack
AU - Ondruschka, Benjamin
AU - Paton, Julian F R
AU - Bardsley, Emma N
AU - Wong, Christopher X
AU - Stables, Simon
AU - Tse, Rexson
N1 - Copyright © 2021 Elsevier B.V. All rights reserved.
PY - 2021/9
Y1 - 2021/9
N2 - Sudden cardiac death (SCD) is the most common natural cause of death. The hypothesized mechanism of death is an arrhythmia precipitated by increased sympathetic outflow. The left stellate ganglion provides sympathetic innervation to the heart and plays a role in arrhythmogensis. We present a SCD with stellate ganglionitis in which the inflammatory cells were characterized. The case was 37-year-old man who died from ischemic and hypertensive heart disease. The left stellate ganglion showed lymphocytic inflammation with features of humoral immune response. This case report provides evidence that stellate ganglionitis can be seen in SCD and raises the possible association between the two.
AB - Sudden cardiac death (SCD) is the most common natural cause of death. The hypothesized mechanism of death is an arrhythmia precipitated by increased sympathetic outflow. The left stellate ganglion provides sympathetic innervation to the heart and plays a role in arrhythmogensis. We present a SCD with stellate ganglionitis in which the inflammatory cells were characterized. The case was 37-year-old man who died from ischemic and hypertensive heart disease. The left stellate ganglion showed lymphocytic inflammation with features of humoral immune response. This case report provides evidence that stellate ganglionitis can be seen in SCD and raises the possible association between the two.
KW - Adult
KW - Arrhythmias, Cardiac
KW - Death, Sudden, Cardiac/etiology
KW - Heart
KW - Heart Rate
KW - Humans
KW - Male
KW - Stellate Ganglion
KW - Sympathetic Nervous System
U2 - 10.1016/j.autneu.2021.102837
DO - 10.1016/j.autneu.2021.102837
M3 - SCORING: Journal article
C2 - 34182293
VL - 234
JO - AUTON NEUROSCI-BASIC
JF - AUTON NEUROSCI-BASIC
SN - 1566-0702
M1 - 102837
ER -