State of the art in the treatment of laryngeal cancer
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State of the art in the treatment of laryngeal cancer. / Jenckel, Friederike; Knecht, Rainald.
In: ANTICANCER RES, Vol. 33, No. 11, 01.11.2013, p. 4701-10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - State of the art in the treatment of laryngeal cancer
AU - Jenckel, Friederike
AU - Knecht, Rainald
PY - 2013/11/1
Y1 - 2013/11/1
N2 - Nowadays clinics can offer patients a variety of different therapy options when laryngeal squamous cell carcinoma is diagnosed histologically. Depending on a variety of different factors, including tumor size, possible metastasis, health status and age of the patient, but also economic factors, a treatment schedule is established. Aim of every treatment decision should be organ larynx preservation and preservation of laryngeal function. The objective of this review is to give an overview of treatment modalities for laryngeal cancer, based not only on traditional but also on the latest studies regarding the treatment of this disease. Surgical approaches, as well as conservative treatment options, such as chemoradiotherapy, induction therapy and target therapy, are discussed. The optimal combination of surgical treatment and conservative treatment modalities need to be further investigated. Furthermore optimal laryngeal function as well as laryngeal preservation must be re-defined.
AB - Nowadays clinics can offer patients a variety of different therapy options when laryngeal squamous cell carcinoma is diagnosed histologically. Depending on a variety of different factors, including tumor size, possible metastasis, health status and age of the patient, but also economic factors, a treatment schedule is established. Aim of every treatment decision should be organ larynx preservation and preservation of laryngeal function. The objective of this review is to give an overview of treatment modalities for laryngeal cancer, based not only on traditional but also on the latest studies regarding the treatment of this disease. Surgical approaches, as well as conservative treatment options, such as chemoradiotherapy, induction therapy and target therapy, are discussed. The optimal combination of surgical treatment and conservative treatment modalities need to be further investigated. Furthermore optimal laryngeal function as well as laryngeal preservation must be re-defined.
KW - Animals
KW - Combined Modality Therapy
KW - Humans
KW - Laryngeal Neoplasms
KW - Prognosis
M3 - SCORING: Journal article
C2 - 24222104
VL - 33
SP - 4701
EP - 4710
JO - ANTICANCER RES
JF - ANTICANCER RES
SN - 0250-7005
IS - 11
ER -