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Spontaneous osteonecrosis of the knee (SONK).

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Spontaneous osteonecrosis of the knee (SONK). / Breer, S; Oheim, R; Krause, M; Marshall, R P; Amling, M; Barvencik, F.

In: KNEE SURG SPORT TR A, Vol. 21, No. 2, 2, 2013, p. 340-345.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Breer, S, Oheim, R, Krause, M, Marshall, RP, Amling, M & Barvencik, F 2013, 'Spontaneous osteonecrosis of the knee (SONK).', KNEE SURG SPORT TR A, vol. 21, no. 2, 2, pp. 340-345. https://doi.org/10.1007/s00167-012-2017-3

APA

Breer, S., Oheim, R., Krause, M., Marshall, R. P., Amling, M., & Barvencik, F. (2013). Spontaneous osteonecrosis of the knee (SONK). KNEE SURG SPORT TR A, 21(2), 340-345. [2]. https://doi.org/10.1007/s00167-012-2017-3

Vancouver

Breer S, Oheim R, Krause M, Marshall RP, Amling M, Barvencik F. Spontaneous osteonecrosis of the knee (SONK). KNEE SURG SPORT TR A. 2013;21(2):340-345. 2. https://doi.org/10.1007/s00167-012-2017-3

Bibtex

@article{4327fc9c02d04d1a8af35a28e1052099,
title = "Spontaneous osteonecrosis of the knee (SONK).",
abstract = "PURPOSE: Spontaneous osteonecrosis of the knee (SONK/Morbus Ahlback) mainly affects the medial condyle of elderly women. It is assumed that localized vascular insufficiency leads to necrosis of the subchondral bone with subsequent disruption of the nutrition supply to the cartilage above. The aetiology remains unclear in detail. Operative treatment procedures compete against non-operative strategies, whereas the outcome is unpredictable in many cases.METHOD: A consecutive case series of five patients suffering from SONK was analysed. All patients underwent a clinical examination, magnetic resonance imaging (MRI) and dual-energy X-ray absorptiometry scan, as well as laboratory analyses and visual analogue scale (VAS) evaluation. Our treatment regime is based on high-dose vitamin D administered orally and intravenous application of 3 mg ibandronate two times within 8 weeks. Another 8 weeks later, all patients were followed up including a follow-up MRI.RESULTS: Within 4 weeks, all patients were free of symptoms. The MRI follow-up showed remission of the bone marrow oedema in every case studied. VAS decreased significantly from 7.4 ± 1.0 pre-interventional to 0.8 ± 1.0 post-interventional. No allergic reactions or other side effects were documented.CONCLUSION: We showed that our treatment regime not only eliminated the pathological findings in the MRI of all cases studied, but also decreased the pain level and functional limitations within a short-time period.LEVEL OF EVIDENCE: IV.",
keywords = "Humans, Male, Female, Middle Aged, Magnetic Resonance Imaging, Administration, Oral, Administration, Intravenous, Bone Density Conservation Agents/administration & dosage, Diphosphonates/administration & dosage, *Femur, Knee, Osteonecrosis/*diagnosis/*drug therapy, Vitamin D/administration & dosage, Humans, Male, Female, Middle Aged, Magnetic Resonance Imaging, Administration, Oral, Administration, Intravenous, Bone Density Conservation Agents/administration & dosage, Diphosphonates/administration & dosage, *Femur, Knee, Osteonecrosis/*diagnosis/*drug therapy, Vitamin D/administration & dosage",
author = "S Breer and R Oheim and M Krause and Marshall, {R P} and M Amling and F Barvencik",
year = "2013",
doi = "10.1007/s00167-012-2017-3",
language = "English",
volume = "21",
pages = "340--345",
journal = "KNEE SURG SPORT TR A",
issn = "0942-2056",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Spontaneous osteonecrosis of the knee (SONK).

AU - Breer, S

AU - Oheim, R

AU - Krause, M

AU - Marshall, R P

AU - Amling, M

AU - Barvencik, F

PY - 2013

Y1 - 2013

N2 - PURPOSE: Spontaneous osteonecrosis of the knee (SONK/Morbus Ahlback) mainly affects the medial condyle of elderly women. It is assumed that localized vascular insufficiency leads to necrosis of the subchondral bone with subsequent disruption of the nutrition supply to the cartilage above. The aetiology remains unclear in detail. Operative treatment procedures compete against non-operative strategies, whereas the outcome is unpredictable in many cases.METHOD: A consecutive case series of five patients suffering from SONK was analysed. All patients underwent a clinical examination, magnetic resonance imaging (MRI) and dual-energy X-ray absorptiometry scan, as well as laboratory analyses and visual analogue scale (VAS) evaluation. Our treatment regime is based on high-dose vitamin D administered orally and intravenous application of 3 mg ibandronate two times within 8 weeks. Another 8 weeks later, all patients were followed up including a follow-up MRI.RESULTS: Within 4 weeks, all patients were free of symptoms. The MRI follow-up showed remission of the bone marrow oedema in every case studied. VAS decreased significantly from 7.4 ± 1.0 pre-interventional to 0.8 ± 1.0 post-interventional. No allergic reactions or other side effects were documented.CONCLUSION: We showed that our treatment regime not only eliminated the pathological findings in the MRI of all cases studied, but also decreased the pain level and functional limitations within a short-time period.LEVEL OF EVIDENCE: IV.

AB - PURPOSE: Spontaneous osteonecrosis of the knee (SONK/Morbus Ahlback) mainly affects the medial condyle of elderly women. It is assumed that localized vascular insufficiency leads to necrosis of the subchondral bone with subsequent disruption of the nutrition supply to the cartilage above. The aetiology remains unclear in detail. Operative treatment procedures compete against non-operative strategies, whereas the outcome is unpredictable in many cases.METHOD: A consecutive case series of five patients suffering from SONK was analysed. All patients underwent a clinical examination, magnetic resonance imaging (MRI) and dual-energy X-ray absorptiometry scan, as well as laboratory analyses and visual analogue scale (VAS) evaluation. Our treatment regime is based on high-dose vitamin D administered orally and intravenous application of 3 mg ibandronate two times within 8 weeks. Another 8 weeks later, all patients were followed up including a follow-up MRI.RESULTS: Within 4 weeks, all patients were free of symptoms. The MRI follow-up showed remission of the bone marrow oedema in every case studied. VAS decreased significantly from 7.4 ± 1.0 pre-interventional to 0.8 ± 1.0 post-interventional. No allergic reactions or other side effects were documented.CONCLUSION: We showed that our treatment regime not only eliminated the pathological findings in the MRI of all cases studied, but also decreased the pain level and functional limitations within a short-time period.LEVEL OF EVIDENCE: IV.

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Magnetic Resonance Imaging

KW - Administration, Oral

KW - Administration, Intravenous

KW - Bone Density Conservation Agents/administration & dosage

KW - Diphosphonates/administration & dosage

KW - Femur

KW - Knee

KW - Osteonecrosis/diagnosis/drug therapy

KW - Vitamin D/administration & dosage

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Magnetic Resonance Imaging

KW - Administration, Oral

KW - Administration, Intravenous

KW - Bone Density Conservation Agents/administration & dosage

KW - Diphosphonates/administration & dosage

KW - Femur

KW - Knee

KW - Osteonecrosis/diagnosis/drug therapy

KW - Vitamin D/administration & dosage

U2 - 10.1007/s00167-012-2017-3

DO - 10.1007/s00167-012-2017-3

M3 - SCORING: Journal article

C2 - 22534975

VL - 21

SP - 340

EP - 345

JO - KNEE SURG SPORT TR A

JF - KNEE SURG SPORT TR A

SN - 0942-2056

IS - 2

M1 - 2

ER -