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Species-dependent premature degradation of absorbable suture materials caused by infection--impact on the choice of thread in vascular surgery

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Species-dependent premature degradation of absorbable suture materials caused by infection--impact on the choice of thread in vascular surgery. / Larena-Avellaneda, A; Debus, E S; Diener, H; Dietz, U A; Franke, S; Thiedel, A.

In: VASA, Vol. 33, No. 3, 08.2004, p. 165-169.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Larena-Avellaneda, A, Debus, ES, Diener, H, Dietz, UA, Franke, S & Thiedel, A 2004, 'Species-dependent premature degradation of absorbable suture materials caused by infection--impact on the choice of thread in vascular surgery', VASA, vol. 33, no. 3, pp. 165-169. https://doi.org/10.1024/0301-1526.33.3.165

APA

Larena-Avellaneda, A., Debus, E. S., Diener, H., Dietz, U. A., Franke, S., & Thiedel, A. (2004). Species-dependent premature degradation of absorbable suture materials caused by infection--impact on the choice of thread in vascular surgery. VASA, 33(3), 165-169. https://doi.org/10.1024/0301-1526.33.3.165

Vancouver

Larena-Avellaneda A, Debus ES, Diener H, Dietz UA, Franke S, Thiedel A. Species-dependent premature degradation of absorbable suture materials caused by infection--impact on the choice of thread in vascular surgery. VASA. 2004 Aug;33(3):165-169. https://doi.org/10.1024/0301-1526.33.3.165

Bibtex

@article{cd2d3700910e4aa7af801c23a683a785,
title = "Species-dependent premature degradation of absorbable suture materials caused by infection--impact on the choice of thread in vascular surgery",
abstract = "BACKGROUND: In case of infection after vascular reconstruction, preference is often given to absorbable suture material with the aim of preventing persistence of infection. We have investigated the functional deficit of absorbable sutures on incubation with various different bacteria.MATERIAL AND METHODS: Four suture materials Dexon bicolor, Vicryl, Maxon and PDS II--were placed in contact with reference bacterial cultures (Staphylococcus aureus, Pseudomonas aeroginosa, E. coli, coagulase-negative staphylococci and Proteus mirabilis). The bacteria were incubated for 7 days at 37 degrees C, together with the suture material. A logarithmic phase (Group A) and a static phase (Group B) were simulated. The linear tensile strength (LTS) of the suture material was measured (Instron Tensiometer).RESULTS: In the case of Staphylococcus aureus, a significant decrease in LTS was established for Dexon bicolor (group A: 31%, group B: 22%), and Vicryl (53% and 43%), but not for the monofilament threads. With regard to the other bacteria, a considerably more dramatic effect was observed: in both groups the braided sutures had completely disintegrated after 7 days. The monofilament sutures also revealed a significant loss of function (Maxon: 88%, PDS II 66%).CONCLUSIONS: The absorbable sutures revealed a premature, species-dependent loss of function due to the presence of the bacteria. On the basis of our results, the use of absorbable threads for vessel sutures in case of infection cannot be recommended, with the exception of monofilament material in a monocultural Staphylococcus aureus infection.",
keywords = "Absorbable Implants/microbiology, Animals, Bacteria/classification, Bacterial Infections/physiopathology, Biocompatible Materials/chemistry, Equipment Failure, Equipment Failure Analysis, Humans, Materials Testing, Species Specificity, Sutures/microbiology, Tensile Strength",
author = "A Larena-Avellaneda and Debus, {E S} and H Diener and Dietz, {U A} and S Franke and A Thiedel",
year = "2004",
month = aug,
doi = "10.1024/0301-1526.33.3.165",
language = "English",
volume = "33",
pages = "165--169",
journal = "VASA",
issn = "0301-1526",
publisher = "Hans Huber",
number = "3",

}

RIS

TY - JOUR

T1 - Species-dependent premature degradation of absorbable suture materials caused by infection--impact on the choice of thread in vascular surgery

AU - Larena-Avellaneda, A

AU - Debus, E S

AU - Diener, H

AU - Dietz, U A

AU - Franke, S

AU - Thiedel, A

PY - 2004/8

Y1 - 2004/8

N2 - BACKGROUND: In case of infection after vascular reconstruction, preference is often given to absorbable suture material with the aim of preventing persistence of infection. We have investigated the functional deficit of absorbable sutures on incubation with various different bacteria.MATERIAL AND METHODS: Four suture materials Dexon bicolor, Vicryl, Maxon and PDS II--were placed in contact with reference bacterial cultures (Staphylococcus aureus, Pseudomonas aeroginosa, E. coli, coagulase-negative staphylococci and Proteus mirabilis). The bacteria were incubated for 7 days at 37 degrees C, together with the suture material. A logarithmic phase (Group A) and a static phase (Group B) were simulated. The linear tensile strength (LTS) of the suture material was measured (Instron Tensiometer).RESULTS: In the case of Staphylococcus aureus, a significant decrease in LTS was established for Dexon bicolor (group A: 31%, group B: 22%), and Vicryl (53% and 43%), but not for the monofilament threads. With regard to the other bacteria, a considerably more dramatic effect was observed: in both groups the braided sutures had completely disintegrated after 7 days. The monofilament sutures also revealed a significant loss of function (Maxon: 88%, PDS II 66%).CONCLUSIONS: The absorbable sutures revealed a premature, species-dependent loss of function due to the presence of the bacteria. On the basis of our results, the use of absorbable threads for vessel sutures in case of infection cannot be recommended, with the exception of monofilament material in a monocultural Staphylococcus aureus infection.

AB - BACKGROUND: In case of infection after vascular reconstruction, preference is often given to absorbable suture material with the aim of preventing persistence of infection. We have investigated the functional deficit of absorbable sutures on incubation with various different bacteria.MATERIAL AND METHODS: Four suture materials Dexon bicolor, Vicryl, Maxon and PDS II--were placed in contact with reference bacterial cultures (Staphylococcus aureus, Pseudomonas aeroginosa, E. coli, coagulase-negative staphylococci and Proteus mirabilis). The bacteria were incubated for 7 days at 37 degrees C, together with the suture material. A logarithmic phase (Group A) and a static phase (Group B) were simulated. The linear tensile strength (LTS) of the suture material was measured (Instron Tensiometer).RESULTS: In the case of Staphylococcus aureus, a significant decrease in LTS was established for Dexon bicolor (group A: 31%, group B: 22%), and Vicryl (53% and 43%), but not for the monofilament threads. With regard to the other bacteria, a considerably more dramatic effect was observed: in both groups the braided sutures had completely disintegrated after 7 days. The monofilament sutures also revealed a significant loss of function (Maxon: 88%, PDS II 66%).CONCLUSIONS: The absorbable sutures revealed a premature, species-dependent loss of function due to the presence of the bacteria. On the basis of our results, the use of absorbable threads for vessel sutures in case of infection cannot be recommended, with the exception of monofilament material in a monocultural Staphylococcus aureus infection.

KW - Absorbable Implants/microbiology

KW - Animals

KW - Bacteria/classification

KW - Bacterial Infections/physiopathology

KW - Biocompatible Materials/chemistry

KW - Equipment Failure

KW - Equipment Failure Analysis

KW - Humans

KW - Materials Testing

KW - Species Specificity

KW - Sutures/microbiology

KW - Tensile Strength

U2 - 10.1024/0301-1526.33.3.165

DO - 10.1024/0301-1526.33.3.165

M3 - SCORING: Journal article

C2 - 15461069

VL - 33

SP - 165

EP - 169

JO - VASA

JF - VASA

SN - 0301-1526

IS - 3

ER -