Skull Base Meningiomas
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Skull Base Meningiomas. / Westphal, Manfred; Saladino, Andrea; Tatagiba, Marcos.
Biological and Clinical Landscape of Meningiomas. ed. / Gelareh Zadeh; Roland Goldbrunner; Boris Krischek; Farshad Nassiri. Vol. 1416 1. ed. Cham : Springer Nature Switzerland AG, 2023. p. 47-68 (ADV EXP MED BIOL).Research output: SCORING: Contribution to book/anthology › Chapter › Research › peer-review
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TY - CHAP
T1 - Skull Base Meningiomas
AU - Westphal, Manfred
AU - Saladino, Andrea
AU - Tatagiba, Marcos
N1 - © 2023. Springer Nature Switzerland AG.
PY - 2023
Y1 - 2023
N2 - Skull base meningiomas are among the most challenging meningiomas to treat clinically due to their deep location, involvement or encasement of adjacent essential neurovascular structures (such as key arteries, cranial nerves, veins, and venous sinuses), and their often-large size prior to diagnosis. Although multimodal treatment strategies continue to evolve with advances in stereotactic and fractionated radiotherapy, surgical resection remains the mainstay of treatment for these tumors. Resection of these tumors however is challenging from a technical standpoint, and requires expertise in several skull-base surgical approaches that rely on adequate bony removal, minimization of brain retraction, and respect for nearby neurovascular structures. These skull base meningiomas originate from a variety of different structures including, but are not limited to: the clinoid processes, tuberculum sellae, dorsum sellae, sphenoid wing, petrous/petroclival area, falcotentorial region, cerebellopontine angle, and foramen magnum. In this chapter, we will cover the common anatomical areas in the skull base from which these tumors arise, and the specific or optimal surgical approaches and other treatment modalities for meningiomas in these such locations.
AB - Skull base meningiomas are among the most challenging meningiomas to treat clinically due to their deep location, involvement or encasement of adjacent essential neurovascular structures (such as key arteries, cranial nerves, veins, and venous sinuses), and their often-large size prior to diagnosis. Although multimodal treatment strategies continue to evolve with advances in stereotactic and fractionated radiotherapy, surgical resection remains the mainstay of treatment for these tumors. Resection of these tumors however is challenging from a technical standpoint, and requires expertise in several skull-base surgical approaches that rely on adequate bony removal, minimization of brain retraction, and respect for nearby neurovascular structures. These skull base meningiomas originate from a variety of different structures including, but are not limited to: the clinoid processes, tuberculum sellae, dorsum sellae, sphenoid wing, petrous/petroclival area, falcotentorial region, cerebellopontine angle, and foramen magnum. In this chapter, we will cover the common anatomical areas in the skull base from which these tumors arise, and the specific or optimal surgical approaches and other treatment modalities for meningiomas in these such locations.
KW - Humans
KW - Meningioma/surgery
KW - Head
KW - Arteries
KW - Brain
KW - Meningeal Neoplasms/surgery
U2 - 10.1007/978-3-031-29750-2_5
DO - 10.1007/978-3-031-29750-2_5
M3 - Chapter
C2 - 37432619
SN - 978-3-031-29749-6
SN - 978-3-031-29752-6
VL - 1416
T3 - ADV EXP MED BIOL
SP - 47
EP - 68
BT - Biological and Clinical Landscape of Meningiomas
A2 - Zadeh, Gelareh
A2 - Goldbrunner, Roland
A2 - Krischek, Boris
A2 - Nassiri, Farshad
PB - Springer Nature Switzerland AG
CY - Cham
ER -
