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Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents.

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Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents. / Tromsdorf, Ulrich I; Bigall, Nadja C; Kaul, Michael; Bruns, Oliver; Nikolic, Marija S; Mollwitz, Birgit; Sperling, Ralph A; Reimer, Rudolph; Hohenberg, Heinz; Parak, Wolfgang J; Förster, Stephan; Beisiegel, Ulrike; Adam, Gerhard; Weller, Horst.

In: NANO LETT, Vol. 7, No. 8, 8, 2007, p. 2422-2427.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Tromsdorf, UI, Bigall, NC, Kaul, M, Bruns, O, Nikolic, MS, Mollwitz, B, Sperling, RA, Reimer, R, Hohenberg, H, Parak, WJ, Förster, S, Beisiegel, U, Adam, G & Weller, H 2007, 'Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents.', NANO LETT, vol. 7, no. 8, 8, pp. 2422-2427. <http://www.ncbi.nlm.nih.gov/pubmed/17658761?dopt=Citation>

APA

Tromsdorf, U. I., Bigall, N. C., Kaul, M., Bruns, O., Nikolic, M. S., Mollwitz, B., Sperling, R. A., Reimer, R., Hohenberg, H., Parak, W. J., Förster, S., Beisiegel, U., Adam, G., & Weller, H. (2007). Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents. NANO LETT, 7(8), 2422-2427. [8]. http://www.ncbi.nlm.nih.gov/pubmed/17658761?dopt=Citation

Vancouver

Tromsdorf UI, Bigall NC, Kaul M, Bruns O, Nikolic MS, Mollwitz B et al. Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents. NANO LETT. 2007;7(8):2422-2427. 8.

Bibtex

@article{09fe888b76384b73878494b0e6548470,
title = "Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents.",
abstract = "Superparamagnetic MnFe2O4 nanocrystals of different sizes were synthesized in high-boiling ether solvent and transferred into water using three different approaches. First, we applied a ligand exchange in order to form a water soluble polymer shell. Second, the particles were embedded into an amphiphilic polymer shell. Third, the nanoparticles were embedded into large micelles formed by lipids. Although all approaches lead to effective negative contrast enhancement, we observed significant differences concerning the magnitude of this effect. The transverse relaxivity, in particular r2*, is greatly higher for the micellar system compared to the polymer-coated particles using same-sized nanoparticles. We also observed an increase in transverse relaxivities with increasing particle size for the polymer-coated nanocrystals. The results are qualitatively compared with theoretical models describing the dependence of relaxivity on the size of magnetic spheres.",
author = "Tromsdorf, {Ulrich I} and Bigall, {Nadja C} and Michael Kaul and Oliver Bruns and Nikolic, {Marija S} and Birgit Mollwitz and Sperling, {Ralph A} and Rudolph Reimer and Heinz Hohenberg and Parak, {Wolfgang J} and Stephan F{\"o}rster and Ulrike Beisiegel and Gerhard Adam and Horst Weller",
year = "2007",
language = "Deutsch",
volume = "7",
pages = "2422--2427",
journal = "NANO LETT",
issn = "1530-6984",
publisher = "American Chemical Society",
number = "8",

}

RIS

TY - JOUR

T1 - Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents.

AU - Tromsdorf, Ulrich I

AU - Bigall, Nadja C

AU - Kaul, Michael

AU - Bruns, Oliver

AU - Nikolic, Marija S

AU - Mollwitz, Birgit

AU - Sperling, Ralph A

AU - Reimer, Rudolph

AU - Hohenberg, Heinz

AU - Parak, Wolfgang J

AU - Förster, Stephan

AU - Beisiegel, Ulrike

AU - Adam, Gerhard

AU - Weller, Horst

PY - 2007

Y1 - 2007

N2 - Superparamagnetic MnFe2O4 nanocrystals of different sizes were synthesized in high-boiling ether solvent and transferred into water using three different approaches. First, we applied a ligand exchange in order to form a water soluble polymer shell. Second, the particles were embedded into an amphiphilic polymer shell. Third, the nanoparticles were embedded into large micelles formed by lipids. Although all approaches lead to effective negative contrast enhancement, we observed significant differences concerning the magnitude of this effect. The transverse relaxivity, in particular r2*, is greatly higher for the micellar system compared to the polymer-coated particles using same-sized nanoparticles. We also observed an increase in transverse relaxivities with increasing particle size for the polymer-coated nanocrystals. The results are qualitatively compared with theoretical models describing the dependence of relaxivity on the size of magnetic spheres.

AB - Superparamagnetic MnFe2O4 nanocrystals of different sizes were synthesized in high-boiling ether solvent and transferred into water using three different approaches. First, we applied a ligand exchange in order to form a water soluble polymer shell. Second, the particles were embedded into an amphiphilic polymer shell. Third, the nanoparticles were embedded into large micelles formed by lipids. Although all approaches lead to effective negative contrast enhancement, we observed significant differences concerning the magnitude of this effect. The transverse relaxivity, in particular r2*, is greatly higher for the micellar system compared to the polymer-coated particles using same-sized nanoparticles. We also observed an increase in transverse relaxivities with increasing particle size for the polymer-coated nanocrystals. The results are qualitatively compared with theoretical models describing the dependence of relaxivity on the size of magnetic spheres.

M3 - SCORING: Zeitschriftenaufsatz

VL - 7

SP - 2422

EP - 2427

JO - NANO LETT

JF - NANO LETT

SN - 1530-6984

IS - 8

M1 - 8

ER -