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Short-term use of "ECMELLA" in the context of fulminant eosinophilic myocarditis with cardiogenic shock

Standard

Short-term use of "ECMELLA" in the context of fulminant eosinophilic myocarditis with cardiogenic shock. / Bohné, Mintje; Chung, Da-Un; Tigges, Eike; van der Schalk, Hendrick; Waddell, Daniela; Schenker, Niklas; Willems, Stephan; Klingel, Karin; Kivelitz, Dietmar; Bahlmann, Edda.

In: BMC CARDIOVASC DISOR, Vol. 20, No. 1, 519, 10.12.2020.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Bohné, M, Chung, D-U, Tigges, E, van der Schalk, H, Waddell, D, Schenker, N, Willems, S, Klingel, K, Kivelitz, D & Bahlmann, E 2020, 'Short-term use of "ECMELLA" in the context of fulminant eosinophilic myocarditis with cardiogenic shock', BMC CARDIOVASC DISOR, vol. 20, no. 1, 519. https://doi.org/10.1186/s12872-020-01808-3

APA

Bohné, M., Chung, D-U., Tigges, E., van der Schalk, H., Waddell, D., Schenker, N., Willems, S., Klingel, K., Kivelitz, D., & Bahlmann, E. (2020). Short-term use of "ECMELLA" in the context of fulminant eosinophilic myocarditis with cardiogenic shock. BMC CARDIOVASC DISOR, 20(1), [519]. https://doi.org/10.1186/s12872-020-01808-3

Vancouver

Bohné M, Chung D-U, Tigges E, van der Schalk H, Waddell D, Schenker N et al. Short-term use of "ECMELLA" in the context of fulminant eosinophilic myocarditis with cardiogenic shock. BMC CARDIOVASC DISOR. 2020 Dec 10;20(1). 519. https://doi.org/10.1186/s12872-020-01808-3

Bibtex

@article{4a631230e4f04f8694089979bb5c63de,
title = "Short-term use of {"}ECMELLA{"} in the context of fulminant eosinophilic myocarditis with cardiogenic shock",
abstract = "BACKGROUND: Eosinophilic myocarditis (EM) is a rare form of myocarditis. Clinical presentation is various, includes cardiogenic shock and can often be fatal. Diagnosis is based on myocardial eosinophilic infiltration in endomyocardial biopsy. Mechanical circulatory support (MCS) is often required in patients suffering from severe cardiogenic shock. Among the available MCS options the {"}ECMELLA{"} concept, a combination of left ventricular venting by Impella{\textregistered} device and extracorporeal life support (ECLS) is possibly able to provide the necessary time frame for diagnostics and initiation of anti-inflammatory medication in patients with fulminant myocarditis.CASE PRESENTATION: We report a case of a 38-year-old woman who was presented to us in severe cardiogenic shock, quickly requiring hemodynamic support by an Impella CP{\textregistered} device. Further dramatic hemodynamic deterioration accompanied by multi-organ dysfunction required escalation of MCS via ECLS as veno-arterial extracorporeal membrane oxygenation (VA-ECMO). After histopathological diagnosis of EM, our patient was put on immunosuppressive therapy with prednisolone. Recovery of both right and left ventricular function allowed explanation of VA-ECMO on day 4 and further hemodynamic improvement allowed removal of the Impella{\textregistered} device on day 9. The patient was discharged after 7 weeks with fully restored cardiac function and in a good neurological state.CONCLUSIONS: In severe cardiac shock due to fulminant EM the ECMELLA concept as bridge-to-recovery seems to be a valid option to provide the required time for diagnostics and specific therapy.",
keywords = "Adult, Combined Modality Therapy, Device Removal, Eosinophilia/complications, Extracorporeal Membrane Oxygenation, Female, Heart-Assist Devices, Humans, Myocarditis/complications, Prosthesis Implantation/instrumentation, Recovery of Function, Shock, Cardiogenic/diagnosis, Treatment Outcome, Ventricular Function, Left",
author = "Mintje Bohn{\'e} and Da-Un Chung and Eike Tigges and {van der Schalk}, Hendrick and Daniela Waddell and Niklas Schenker and Stephan Willems and Karin Klingel and Dietmar Kivelitz and Edda Bahlmann",
year = "2020",
month = dec,
day = "10",
doi = "10.1186/s12872-020-01808-3",
language = "English",
volume = "20",
journal = "BMC CARDIOVASC DISOR",
issn = "1471-2261",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Short-term use of "ECMELLA" in the context of fulminant eosinophilic myocarditis with cardiogenic shock

AU - Bohné, Mintje

AU - Chung, Da-Un

AU - Tigges, Eike

AU - van der Schalk, Hendrick

AU - Waddell, Daniela

AU - Schenker, Niklas

AU - Willems, Stephan

AU - Klingel, Karin

AU - Kivelitz, Dietmar

AU - Bahlmann, Edda

PY - 2020/12/10

Y1 - 2020/12/10

N2 - BACKGROUND: Eosinophilic myocarditis (EM) is a rare form of myocarditis. Clinical presentation is various, includes cardiogenic shock and can often be fatal. Diagnosis is based on myocardial eosinophilic infiltration in endomyocardial biopsy. Mechanical circulatory support (MCS) is often required in patients suffering from severe cardiogenic shock. Among the available MCS options the "ECMELLA" concept, a combination of left ventricular venting by Impella® device and extracorporeal life support (ECLS) is possibly able to provide the necessary time frame for diagnostics and initiation of anti-inflammatory medication in patients with fulminant myocarditis.CASE PRESENTATION: We report a case of a 38-year-old woman who was presented to us in severe cardiogenic shock, quickly requiring hemodynamic support by an Impella CP® device. Further dramatic hemodynamic deterioration accompanied by multi-organ dysfunction required escalation of MCS via ECLS as veno-arterial extracorporeal membrane oxygenation (VA-ECMO). After histopathological diagnosis of EM, our patient was put on immunosuppressive therapy with prednisolone. Recovery of both right and left ventricular function allowed explanation of VA-ECMO on day 4 and further hemodynamic improvement allowed removal of the Impella® device on day 9. The patient was discharged after 7 weeks with fully restored cardiac function and in a good neurological state.CONCLUSIONS: In severe cardiac shock due to fulminant EM the ECMELLA concept as bridge-to-recovery seems to be a valid option to provide the required time for diagnostics and specific therapy.

AB - BACKGROUND: Eosinophilic myocarditis (EM) is a rare form of myocarditis. Clinical presentation is various, includes cardiogenic shock and can often be fatal. Diagnosis is based on myocardial eosinophilic infiltration in endomyocardial biopsy. Mechanical circulatory support (MCS) is often required in patients suffering from severe cardiogenic shock. Among the available MCS options the "ECMELLA" concept, a combination of left ventricular venting by Impella® device and extracorporeal life support (ECLS) is possibly able to provide the necessary time frame for diagnostics and initiation of anti-inflammatory medication in patients with fulminant myocarditis.CASE PRESENTATION: We report a case of a 38-year-old woman who was presented to us in severe cardiogenic shock, quickly requiring hemodynamic support by an Impella CP® device. Further dramatic hemodynamic deterioration accompanied by multi-organ dysfunction required escalation of MCS via ECLS as veno-arterial extracorporeal membrane oxygenation (VA-ECMO). After histopathological diagnosis of EM, our patient was put on immunosuppressive therapy with prednisolone. Recovery of both right and left ventricular function allowed explanation of VA-ECMO on day 4 and further hemodynamic improvement allowed removal of the Impella® device on day 9. The patient was discharged after 7 weeks with fully restored cardiac function and in a good neurological state.CONCLUSIONS: In severe cardiac shock due to fulminant EM the ECMELLA concept as bridge-to-recovery seems to be a valid option to provide the required time for diagnostics and specific therapy.

KW - Adult

KW - Combined Modality Therapy

KW - Device Removal

KW - Eosinophilia/complications

KW - Extracorporeal Membrane Oxygenation

KW - Female

KW - Heart-Assist Devices

KW - Humans

KW - Myocarditis/complications

KW - Prosthesis Implantation/instrumentation

KW - Recovery of Function

KW - Shock, Cardiogenic/diagnosis

KW - Treatment Outcome

KW - Ventricular Function, Left

U2 - 10.1186/s12872-020-01808-3

DO - 10.1186/s12872-020-01808-3

M3 - SCORING: Journal article

C2 - 33302874

VL - 20

JO - BMC CARDIOVASC DISOR

JF - BMC CARDIOVASC DISOR

SN - 1471-2261

IS - 1

M1 - 519

ER -