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Short Report: Serum Levels of Neopterin during Antimicrobial Treatment for Mycobacterium ulcerans Infection

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Short Report: Serum Levels of Neopterin during Antimicrobial Treatment for Mycobacterium ulcerans Infection. / de Zeeuw, Janine; Duggirala, Sridevi; Nienhuis, Willemien A; Abass, K Mohammed; Tuah, Wilson; Omansen, Till F.; van der Werf, Tjip S; Stienstra, Ymkje.

In: AM J TROP MED HYG, Vol. 89, No. 3, 09.2013, p. 498-500.

Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

Harvard

de Zeeuw, J, Duggirala, S, Nienhuis, WA, Abass, KM, Tuah, W, Omansen, TF, van der Werf, TS & Stienstra, Y 2013, 'Short Report: Serum Levels of Neopterin during Antimicrobial Treatment for Mycobacterium ulcerans Infection', AM J TROP MED HYG, vol. 89, no. 3, pp. 498-500. https://doi.org/10.4269/ajtmh.12-0599

APA

de Zeeuw, J., Duggirala, S., Nienhuis, W. A., Abass, K. M., Tuah, W., Omansen, T. F., van der Werf, T. S., & Stienstra, Y. (2013). Short Report: Serum Levels of Neopterin during Antimicrobial Treatment for Mycobacterium ulcerans Infection. AM J TROP MED HYG, 89(3), 498-500. https://doi.org/10.4269/ajtmh.12-0599

Vancouver

de Zeeuw J, Duggirala S, Nienhuis WA, Abass KM, Tuah W, Omansen TF et al. Short Report: Serum Levels of Neopterin during Antimicrobial Treatment for Mycobacterium ulcerans Infection. AM J TROP MED HYG. 2013 Sep;89(3):498-500. https://doi.org/10.4269/ajtmh.12-0599

Bibtex

@article{0709c40b1e2f48598ce88b1d2299c152,
title = "Short Report: Serum Levels of Neopterin during Antimicrobial Treatment for Mycobacterium ulcerans Infection",
abstract = "Neopterin is closely associated with activation of the cellular immune system. Neopterin levels differed between controls and patients with Buruli ulcer disease. No differences between patients with or without paradoxical responses were observed. Therefore, neopterin has no value in detecting paradoxical responses among patients with limited Buruli ulcer disease. Neopterin levels were lower in patients receiving clarithromycin. This finding might indicate a slower cellular immune recovery, with possible consequences in future therapy with clarithromycin.",
keywords = "Anti-Bacterial Agents/therapeutic use, Buruli Ulcer/drug therapy, Case-Control Studies, Clarithromycin/therapeutic use, Female, Humans, Male, Mycobacterium ulcerans/drug effects, Neopterin/blood, Randomized Controlled Trials as Topic, Time Factors, Treatment Outcome",
author = "{de Zeeuw}, Janine and Sridevi Duggirala and Nienhuis, {Willemien A} and Abass, {K Mohammed} and Wilson Tuah and Omansen, {Till F.} and {van der Werf}, {Tjip S} and Ymkje Stienstra",
year = "2013",
month = sep,
doi = "10.4269/ajtmh.12-0599",
language = "English",
volume = "89",
pages = "498--500",
journal = "AM J TROP MED HYG",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "3",

}

RIS

TY - JOUR

T1 - Short Report: Serum Levels of Neopterin during Antimicrobial Treatment for Mycobacterium ulcerans Infection

AU - de Zeeuw, Janine

AU - Duggirala, Sridevi

AU - Nienhuis, Willemien A

AU - Abass, K Mohammed

AU - Tuah, Wilson

AU - Omansen, Till F.

AU - van der Werf, Tjip S

AU - Stienstra, Ymkje

PY - 2013/9

Y1 - 2013/9

N2 - Neopterin is closely associated with activation of the cellular immune system. Neopterin levels differed between controls and patients with Buruli ulcer disease. No differences between patients with or without paradoxical responses were observed. Therefore, neopterin has no value in detecting paradoxical responses among patients with limited Buruli ulcer disease. Neopterin levels were lower in patients receiving clarithromycin. This finding might indicate a slower cellular immune recovery, with possible consequences in future therapy with clarithromycin.

AB - Neopterin is closely associated with activation of the cellular immune system. Neopterin levels differed between controls and patients with Buruli ulcer disease. No differences between patients with or without paradoxical responses were observed. Therefore, neopterin has no value in detecting paradoxical responses among patients with limited Buruli ulcer disease. Neopterin levels were lower in patients receiving clarithromycin. This finding might indicate a slower cellular immune recovery, with possible consequences in future therapy with clarithromycin.

KW - Anti-Bacterial Agents/therapeutic use

KW - Buruli Ulcer/drug therapy

KW - Case-Control Studies

KW - Clarithromycin/therapeutic use

KW - Female

KW - Humans

KW - Male

KW - Mycobacterium ulcerans/drug effects

KW - Neopterin/blood

KW - Randomized Controlled Trials as Topic

KW - Time Factors

KW - Treatment Outcome

U2 - 10.4269/ajtmh.12-0599

DO - 10.4269/ajtmh.12-0599

M3 - Other (editorial matter etc.)

C2 - 23836576

VL - 89

SP - 498

EP - 500

JO - AM J TROP MED HYG

JF - AM J TROP MED HYG

SN - 0002-9637

IS - 3

ER -