Sexual Dysfunction in Unmedicated Patients with Schizophrenia and in Healthy Controls
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Sexual Dysfunction in Unmedicated Patients with Schizophrenia and in Healthy Controls. / Dembler-Stamm, Theresa; Fiebig, Jana; Heinz, Andreas; Gallinat, Jürgen.
In: PHARMACOPSYCHIATRY, Vol. 51, No. 6, 11.2018, p. 251-256.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Sexual Dysfunction in Unmedicated Patients with Schizophrenia and in Healthy Controls
AU - Dembler-Stamm, Theresa
AU - Fiebig, Jana
AU - Heinz, Andreas
AU - Gallinat, Jürgen
N1 - © Georg Thieme Verlag KG Stuttgart · New York.
PY - 2018/11
Y1 - 2018/11
N2 - INTRODUCTION: Sexual dysfunction figures prominently in patients with schizophrenia; however, medication effects may play a role. The objective of this case control study was to assess differences in the presence of sexual dysfunction in unmedicated patients with schizophrenia versus healthy controls.METHODS: Sexual dysfunction was assessed using the Derogatis Inventory for Sexual Function self-rating in a cross-sectional design controlling for age and gender effects. A brief sexual anamnesis was applied to describe the psychosocial background of the mostly male sample further.RESULTS: Results show a significant difference with patients reporting more problems in most domains and with a significant correlation between severity of psychosis (Positive and Negative Syndrome Scale total scores) and the impairment of orgasm experience. The study revealed reduced sexual activities and less pleasure during sexual activities of patients.DISCUSSION: This study implies that schizophrenia has an impact on the presence of sexual dysfunction and that sexual dysfunction is partly independent of antipsychotic treatment. Since the sample consisted mostly of first-episode males, conclusions might only be valid for this subgroup.
AB - INTRODUCTION: Sexual dysfunction figures prominently in patients with schizophrenia; however, medication effects may play a role. The objective of this case control study was to assess differences in the presence of sexual dysfunction in unmedicated patients with schizophrenia versus healthy controls.METHODS: Sexual dysfunction was assessed using the Derogatis Inventory for Sexual Function self-rating in a cross-sectional design controlling for age and gender effects. A brief sexual anamnesis was applied to describe the psychosocial background of the mostly male sample further.RESULTS: Results show a significant difference with patients reporting more problems in most domains and with a significant correlation between severity of psychosis (Positive and Negative Syndrome Scale total scores) and the impairment of orgasm experience. The study revealed reduced sexual activities and less pleasure during sexual activities of patients.DISCUSSION: This study implies that schizophrenia has an impact on the presence of sexual dysfunction and that sexual dysfunction is partly independent of antipsychotic treatment. Since the sample consisted mostly of first-episode males, conclusions might only be valid for this subgroup.
KW - Journal Article
U2 - 10.1055/s-0044-100627
DO - 10.1055/s-0044-100627
M3 - SCORING: Journal article
C2 - 29378348
VL - 51
SP - 251
EP - 256
JO - PHARMACOPSYCHIATRY
JF - PHARMACOPSYCHIATRY
SN - 0176-3679
IS - 6
ER -