Severe Cobalt Intoxication Due to Prosthesis Wear in Repeated Total Hip Arthroplasty.
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Severe Cobalt Intoxication Due to Prosthesis Wear in Repeated Total Hip Arthroplasty. / Oldenburg, Marcus; Wegner, Ralf; Baur, Xaver.
In: J ARTHROPLASTY, 2008.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Severe Cobalt Intoxication Due to Prosthesis Wear in Repeated Total Hip Arthroplasty.
AU - Oldenburg, Marcus
AU - Wegner, Ralf
AU - Baur, Xaver
PY - 2008
Y1 - 2008
N2 - Our study describes a 55-year-old man with a total hip prosthesis (ceramic femoral head and polyethylene [PE] inlay). After a fall, the ceramic head broke into several pieces, and a subsequent revision surgery with metal femoral head and PE inlay was performed. Three months later, the so far healthy patient complained of multiorganic symptoms. The subsequent clinical examinations revealed hypothyroidism, peripheral neuropathy, and cardiomyopathy for the first time. In a second revision surgery, a massive deterioration of the metal femoral head by overlooked particles of the broken ceramic head was found. The cobalt concentration in blood exceeded a never before observed level. After replacement of the scraped femoral head, the cobalt concentration decreased considerably, and most of the symptoms disappeared.
AB - Our study describes a 55-year-old man with a total hip prosthesis (ceramic femoral head and polyethylene [PE] inlay). After a fall, the ceramic head broke into several pieces, and a subsequent revision surgery with metal femoral head and PE inlay was performed. Three months later, the so far healthy patient complained of multiorganic symptoms. The subsequent clinical examinations revealed hypothyroidism, peripheral neuropathy, and cardiomyopathy for the first time. In a second revision surgery, a massive deterioration of the metal femoral head by overlooked particles of the broken ceramic head was found. The cobalt concentration in blood exceeded a never before observed level. After replacement of the scraped femoral head, the cobalt concentration decreased considerably, and most of the symptoms disappeared.
M3 - SCORING: Zeitschriftenaufsatz
JO - J ARTHROPLASTY
JF - J ARTHROPLASTY
SN - 0883-5403
ER -
