Severe bronchial reaction to provocation with fish and crustaceans
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Severe bronchial reaction to provocation with fish and crustaceans. / Preisser, Alexandra M; Kraft, Alexander M; Harth, Volker.
In: Allergologie select, Vol. 4, 02.12.2020, p. 118-123.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Severe bronchial reaction to provocation with fish and crustaceans
AU - Preisser, Alexandra M
AU - Kraft, Alexander M
AU - Harth, Volker
N1 - © Dustri-Verlag Dr. K. Feistle.
PY - 2020/12/2
Y1 - 2020/12/2
N2 - The specific inhalation challenge (SIC), a workplace-related inhalation exposure test, is used to identify allergic asthma when symptoms such as coughing, wheezing, or dyspnea occur at the workplace. Its use is risky. A cook (28 years old) has been complaining of rhinoconjunctivitis and contact urticaria while preparing seafood for 3 years. He continues to work, now wears gloves, no longer tastes fish dishes, and receives anti-obstructive therapy (ICS, LABA). Methacholine (MCH) testing for bronchial hyperreactivity (BHR) shows mild BHR (PD100;sRaw: 0.28 mg MCH), skin and blood tests show type I sensitization to fish and crustacean proteins. In SIC with fried shrimps, rhinoconjunctivitis, coughing and distance wheezing, FEV1 drop > 20%, sRaw increase to 9.6 kPa*s and angioedema occur. Since routine tests showed only a moderate BHR, the suspicion of an occupational disease was formulated very late in the medical examination process. Only the SIC showed the severity of the cook's bronchial asthma.
AB - The specific inhalation challenge (SIC), a workplace-related inhalation exposure test, is used to identify allergic asthma when symptoms such as coughing, wheezing, or dyspnea occur at the workplace. Its use is risky. A cook (28 years old) has been complaining of rhinoconjunctivitis and contact urticaria while preparing seafood for 3 years. He continues to work, now wears gloves, no longer tastes fish dishes, and receives anti-obstructive therapy (ICS, LABA). Methacholine (MCH) testing for bronchial hyperreactivity (BHR) shows mild BHR (PD100;sRaw: 0.28 mg MCH), skin and blood tests show type I sensitization to fish and crustacean proteins. In SIC with fried shrimps, rhinoconjunctivitis, coughing and distance wheezing, FEV1 drop > 20%, sRaw increase to 9.6 kPa*s and angioedema occur. Since routine tests showed only a moderate BHR, the suspicion of an occupational disease was formulated very late in the medical examination process. Only the SIC showed the severity of the cook's bronchial asthma.
U2 - 10.5414/ALX02129E
DO - 10.5414/ALX02129E
M3 - SCORING: Journal article
C2 - 33326507
VL - 4
SP - 118
EP - 123
JO - Allergologie select
JF - Allergologie select
SN - 2512-8957
ER -