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Serum brain-derived neurotrophic factor (BDNF) is not regulated by testosterone in transmen

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Serum brain-derived neurotrophic factor (BDNF) is not regulated by testosterone in transmen. / Auer, Matthias; Hellweg, Rainer; Briken, Peer; Stalla, Günter K.; T'Sjoen, Guy; Fuß, Johannes.

In: BIOL SEX DIFFER, Vol. 7, No. 1, 08.01.2016, p. 1-6.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Auer, M, Hellweg, R, Briken, P, Stalla, GK, T'Sjoen, G & Fuß, J 2016, 'Serum brain-derived neurotrophic factor (BDNF) is not regulated by testosterone in transmen', BIOL SEX DIFFER, vol. 7, no. 1, pp. 1-6. https://doi.org/10.1186/s13293-015-0055-5

APA

Auer, M., Hellweg, R., Briken, P., Stalla, G. K., T'Sjoen, G., & Fuß, J. (2016). Serum brain-derived neurotrophic factor (BDNF) is not regulated by testosterone in transmen. BIOL SEX DIFFER, 7(1), 1-6. https://doi.org/10.1186/s13293-015-0055-5

Vancouver

Auer M, Hellweg R, Briken P, Stalla GK, T'Sjoen G, Fuß J. Serum brain-derived neurotrophic factor (BDNF) is not regulated by testosterone in transmen. BIOL SEX DIFFER. 2016 Jan 8;7(1):1-6. https://doi.org/10.1186/s13293-015-0055-5

Bibtex

@article{531b5ca93e464a59a810559bc339e649,
title = "Serum brain-derived neurotrophic factor (BDNF) is not regulated by testosterone in transmen",
abstract = "Brain morphology significantly differs between the sexes. It has been shown before that some of these differences are attributable to the sex-specific hormonal milieu. Brain-derived neurotrophic factor (BDNF) is involved in myriads of neuroplastic processes and shows a sexual dimorphism. Transsexual persons may serve as a model to study sex steroid-mediated effects on brain plasticity. We have recently demonstrated that serum levels of BDNF are reduced in transwomen following 12 months of cross-sex hormone treatment. We now wanted to look at the effects of testosterone treatment on BDNF in transmen. In contrast to our initial hypothesis, BDNF levels did not significantly change, despite dramatic changes in the sex-hormonal milieu. Our data indicate that testosterone does not seem to play a major role in the regulation of BDNF in females. ",
author = "Matthias Auer and Rainer Hellweg and Peer Briken and Stalla, {G{\"u}nter K.} and Guy T'Sjoen and Johannes Fu{\ss}",
year = "2016",
month = jan,
day = "8",
doi = "10.1186/s13293-015-0055-5",
language = "English",
volume = "7",
pages = "1--6",
journal = "BIOL SEX DIFFER",
issn = "2042-6410",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Serum brain-derived neurotrophic factor (BDNF) is not regulated by testosterone in transmen

AU - Auer, Matthias

AU - Hellweg, Rainer

AU - Briken, Peer

AU - Stalla, Günter K.

AU - T'Sjoen, Guy

AU - Fuß, Johannes

PY - 2016/1/8

Y1 - 2016/1/8

N2 - Brain morphology significantly differs between the sexes. It has been shown before that some of these differences are attributable to the sex-specific hormonal milieu. Brain-derived neurotrophic factor (BDNF) is involved in myriads of neuroplastic processes and shows a sexual dimorphism. Transsexual persons may serve as a model to study sex steroid-mediated effects on brain plasticity. We have recently demonstrated that serum levels of BDNF are reduced in transwomen following 12 months of cross-sex hormone treatment. We now wanted to look at the effects of testosterone treatment on BDNF in transmen. In contrast to our initial hypothesis, BDNF levels did not significantly change, despite dramatic changes in the sex-hormonal milieu. Our data indicate that testosterone does not seem to play a major role in the regulation of BDNF in females.

AB - Brain morphology significantly differs between the sexes. It has been shown before that some of these differences are attributable to the sex-specific hormonal milieu. Brain-derived neurotrophic factor (BDNF) is involved in myriads of neuroplastic processes and shows a sexual dimorphism. Transsexual persons may serve as a model to study sex steroid-mediated effects on brain plasticity. We have recently demonstrated that serum levels of BDNF are reduced in transwomen following 12 months of cross-sex hormone treatment. We now wanted to look at the effects of testosterone treatment on BDNF in transmen. In contrast to our initial hypothesis, BDNF levels did not significantly change, despite dramatic changes in the sex-hormonal milieu. Our data indicate that testosterone does not seem to play a major role in the regulation of BDNF in females.

U2 - 10.1186/s13293-015-0055-5

DO - 10.1186/s13293-015-0055-5

M3 - SCORING: Journal article

VL - 7

SP - 1

EP - 6

JO - BIOL SEX DIFFER

JF - BIOL SEX DIFFER

SN - 2042-6410

IS - 1

ER -