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Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis.

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Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis. / Ericson, Kim Göransdotter; Fadeel, Bengt; Andersson, Mats; Gudmundsson, Gudmundur H; Gürgey, Aytemiz; Yalman, Nevin; Janka-Schaub, Gritta; Nordenskjöld, Magnus; Henter, Jan-Inge.

In: HUM GENET, Vol. 112, No. 1, 1, 2003, p. 98-99.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Ericson, KG, Fadeel, B, Andersson, M, Gudmundsson, GH, Gürgey, A, Yalman, N, Janka-Schaub, G, Nordenskjöld, M & Henter, J-I 2003, 'Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis.', HUM GENET, vol. 112, no. 1, 1, pp. 98-99. <http://www.ncbi.nlm.nih.gov/pubmed/12483306?dopt=Citation>

APA

Ericson, K. G., Fadeel, B., Andersson, M., Gudmundsson, G. H., Gürgey, A., Yalman, N., Janka-Schaub, G., Nordenskjöld, M., & Henter, J-I. (2003). Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis. HUM GENET, 112(1), 98-99. [1]. http://www.ncbi.nlm.nih.gov/pubmed/12483306?dopt=Citation

Vancouver

Ericson KG, Fadeel B, Andersson M, Gudmundsson GH, Gürgey A, Yalman N et al. Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis. HUM GENET. 2003;112(1):98-99. 1.

Bibtex

@article{b1db9eb3e55644078543d1d02357b03e,
title = "Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis.",
abstract = "Familial hemophagocytic lymphohistiocytosis (FHL) is an autosomal recessive disorder of immune regulation. Mutations in the gene encoding perforin were previously identified in a subset of FHL patients. The present analysis of two novel candidate genes, granzyme B and granulysin, by direct sequencing in a total of 16 FHL families, disclosed several sequence variations. However, none of these sequence variations were associated with the manifestations of FHL. These data do not support the notion that granulysin and granzyme B are candidate genes for FHL.",
author = "Ericson, {Kim G{\"o}ransdotter} and Bengt Fadeel and Mats Andersson and Gudmundsson, {Gudmundur H} and Aytemiz G{\"u}rgey and Nevin Yalman and Gritta Janka-Schaub and Magnus Nordenskj{\"o}ld and Jan-Inge Henter",
year = "2003",
language = "Deutsch",
volume = "112",
pages = "98--99",
journal = "HUM GENET",
issn = "0340-6717",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis.

AU - Ericson, Kim Göransdotter

AU - Fadeel, Bengt

AU - Andersson, Mats

AU - Gudmundsson, Gudmundur H

AU - Gürgey, Aytemiz

AU - Yalman, Nevin

AU - Janka-Schaub, Gritta

AU - Nordenskjöld, Magnus

AU - Henter, Jan-Inge

PY - 2003

Y1 - 2003

N2 - Familial hemophagocytic lymphohistiocytosis (FHL) is an autosomal recessive disorder of immune regulation. Mutations in the gene encoding perforin were previously identified in a subset of FHL patients. The present analysis of two novel candidate genes, granzyme B and granulysin, by direct sequencing in a total of 16 FHL families, disclosed several sequence variations. However, none of these sequence variations were associated with the manifestations of FHL. These data do not support the notion that granulysin and granzyme B are candidate genes for FHL.

AB - Familial hemophagocytic lymphohistiocytosis (FHL) is an autosomal recessive disorder of immune regulation. Mutations in the gene encoding perforin were previously identified in a subset of FHL patients. The present analysis of two novel candidate genes, granzyme B and granulysin, by direct sequencing in a total of 16 FHL families, disclosed several sequence variations. However, none of these sequence variations were associated with the manifestations of FHL. These data do not support the notion that granulysin and granzyme B are candidate genes for FHL.

M3 - SCORING: Zeitschriftenaufsatz

VL - 112

SP - 98

EP - 99

JO - HUM GENET

JF - HUM GENET

SN - 0340-6717

IS - 1

M1 - 1

ER -