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Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition

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Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition. / Deng, Wanlu; Rolls, Edmund T; Ji, Xiaoxi; Robbins, Trevor W; Banaschewski, Tobias; Bokde, Arun L W; Bromberg, Uli; Buechel, Christian; Desrivières, Sylvane; Conrod, Patricia; Flor, Herta; Frouin, Vincent; Gallinat, Juergen; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Ittermann, Bernd; Martinot, Jean-Luc; Lemaitre, Herve; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Poustka, Luise; Smolka, Michael N; Walter, Henrik; Whelan, Robert; Schumann, Gunter; Feng, Jianfeng.

In: HUM BRAIN MAPP, 07.2017.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Deng, W, Rolls, ET, Ji, X, Robbins, TW, Banaschewski, T, Bokde, ALW, Bromberg, U, Buechel, C, Desrivières, S, Conrod, P, Flor, H, Frouin, V, Gallinat, J, Garavan, H, Gowland, P, Heinz, A, Ittermann, B, Martinot, J-L, Lemaitre, H, Nees, F, Papadopoulos Orfanos, D, Poustka, L, Smolka, MN, Walter, H, Whelan, R, Schumann, G & Feng, J 2017, 'Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition', HUM BRAIN MAPP. https://doi.org/10.1002/hbm.23607

APA

Deng, W., Rolls, E. T., Ji, X., Robbins, T. W., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Buechel, C., Desrivières, S., Conrod, P., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J-L., Lemaitre, H., ... Feng, J. (2017). Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition. HUM BRAIN MAPP. https://doi.org/10.1002/hbm.23607

Vancouver

Deng W, Rolls ET, Ji X, Robbins TW, Banaschewski T, Bokde ALW et al. Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition. HUM BRAIN MAPP. 2017 Jul. https://doi.org/10.1002/hbm.23607

Bibtex

@article{689b81e900314a6fa5117d448e0b80cb,
title = "Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition",
abstract = "To analyze the involvement of different brain regions in behavioral inhibition and impulsiveness, differences in activation were investigated in fMRI data from a response inhibition task, the stop-signal task, in 1709 participants. First, areas activated more in stop-success (SS) than stop-failure (SF) included the lateral orbitofrontal cortex (OFC) extending into the inferior frontal gyrus (ventrolateral prefrontal cortex, BA 47/12), and the dorsolateral prefrontal cortex (DLPFC). Second, the anterior cingulate and anterior insula (AI) were activated more on failure trials, specifically in SF versus SS. The interaction between brain region and SS versus SF activations was significant (P = 5.6 * 10-8 ). The results provide new evidence from this {"}big data{"} investigation consistent with the hypotheses that the lateral OFC is involved in the stop-related processing that inhibits the action; that the DLPFC is involved in attentional processes that influence task performance; and that the AI and anterior cingulate are involved in emotional processes when failure occurs. The investigation thus emphasizes the role of the human lateral OFC BA 47/12 in changing behavior, and inhibiting behavior when necessary. A very similar area in BA47/12 is involved in changing behavior when an expected reward is not obtained, and has been shown to have high functional connectivity in depression. Hum Brain Mapp, 2017. {\textcopyright} 2017 Wiley Periodicals, Inc.",
keywords = "Journal Article",
author = "Wanlu Deng and Rolls, {Edmund T} and Xiaoxi Ji and Robbins, {Trevor W} and Tobias Banaschewski and Bokde, {Arun L W} and Uli Bromberg and Christian Buechel and Sylvane Desrivi{\`e}res and Patricia Conrod and Herta Flor and Vincent Frouin and Juergen Gallinat and Hugh Garavan and Penny Gowland and Andreas Heinz and Bernd Ittermann and Jean-Luc Martinot and Herve Lemaitre and Frauke Nees and {Papadopoulos Orfanos}, Dimitri and Luise Poustka and Smolka, {Michael N} and Henrik Walter and Robert Whelan and Gunter Schumann and Jianfeng Feng",
note = "{\textcopyright} 2017 Wiley Periodicals, Inc.",
year = "2017",
month = jul,
doi = "10.1002/hbm.23607",
language = "English",
journal = "HUM BRAIN MAPP",
issn = "1065-9471",
publisher = "Wiley-Liss Inc.",

}

RIS

TY - JOUR

T1 - Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition

AU - Deng, Wanlu

AU - Rolls, Edmund T

AU - Ji, Xiaoxi

AU - Robbins, Trevor W

AU - Banaschewski, Tobias

AU - Bokde, Arun L W

AU - Bromberg, Uli

AU - Buechel, Christian

AU - Desrivières, Sylvane

AU - Conrod, Patricia

AU - Flor, Herta

AU - Frouin, Vincent

AU - Gallinat, Juergen

AU - Garavan, Hugh

AU - Gowland, Penny

AU - Heinz, Andreas

AU - Ittermann, Bernd

AU - Martinot, Jean-Luc

AU - Lemaitre, Herve

AU - Nees, Frauke

AU - Papadopoulos Orfanos, Dimitri

AU - Poustka, Luise

AU - Smolka, Michael N

AU - Walter, Henrik

AU - Whelan, Robert

AU - Schumann, Gunter

AU - Feng, Jianfeng

N1 - © 2017 Wiley Periodicals, Inc.

PY - 2017/7

Y1 - 2017/7

N2 - To analyze the involvement of different brain regions in behavioral inhibition and impulsiveness, differences in activation were investigated in fMRI data from a response inhibition task, the stop-signal task, in 1709 participants. First, areas activated more in stop-success (SS) than stop-failure (SF) included the lateral orbitofrontal cortex (OFC) extending into the inferior frontal gyrus (ventrolateral prefrontal cortex, BA 47/12), and the dorsolateral prefrontal cortex (DLPFC). Second, the anterior cingulate and anterior insula (AI) were activated more on failure trials, specifically in SF versus SS. The interaction between brain region and SS versus SF activations was significant (P = 5.6 * 10-8 ). The results provide new evidence from this "big data" investigation consistent with the hypotheses that the lateral OFC is involved in the stop-related processing that inhibits the action; that the DLPFC is involved in attentional processes that influence task performance; and that the AI and anterior cingulate are involved in emotional processes when failure occurs. The investigation thus emphasizes the role of the human lateral OFC BA 47/12 in changing behavior, and inhibiting behavior when necessary. A very similar area in BA47/12 is involved in changing behavior when an expected reward is not obtained, and has been shown to have high functional connectivity in depression. Hum Brain Mapp, 2017. © 2017 Wiley Periodicals, Inc.

AB - To analyze the involvement of different brain regions in behavioral inhibition and impulsiveness, differences in activation were investigated in fMRI data from a response inhibition task, the stop-signal task, in 1709 participants. First, areas activated more in stop-success (SS) than stop-failure (SF) included the lateral orbitofrontal cortex (OFC) extending into the inferior frontal gyrus (ventrolateral prefrontal cortex, BA 47/12), and the dorsolateral prefrontal cortex (DLPFC). Second, the anterior cingulate and anterior insula (AI) were activated more on failure trials, specifically in SF versus SS. The interaction between brain region and SS versus SF activations was significant (P = 5.6 * 10-8 ). The results provide new evidence from this "big data" investigation consistent with the hypotheses that the lateral OFC is involved in the stop-related processing that inhibits the action; that the DLPFC is involved in attentional processes that influence task performance; and that the AI and anterior cingulate are involved in emotional processes when failure occurs. The investigation thus emphasizes the role of the human lateral OFC BA 47/12 in changing behavior, and inhibiting behavior when necessary. A very similar area in BA47/12 is involved in changing behavior when an expected reward is not obtained, and has been shown to have high functional connectivity in depression. Hum Brain Mapp, 2017. © 2017 Wiley Periodicals, Inc.

KW - Journal Article

U2 - 10.1002/hbm.23607

DO - 10.1002/hbm.23607

M3 - SCORING: Journal article

C2 - 28429498

JO - HUM BRAIN MAPP

JF - HUM BRAIN MAPP

SN - 1065-9471

ER -