Research ExplorerPublicationsSentinel lymph-node biopsy in head and neck cancer.

Sentinel lymph-node biopsy in head and neck cancer.

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Sentinel lymph-node biopsy in head and neck cancer. / Höft, S; Maune, S; Muhle, C; Brenner, Winfried; Czech, N; Kampen, W-U; Jänig, U; Laudien, M; Gottschlich, S; Ambrosch, P.

In: BRIT J CANCER, Vol. 91, No. 1, 1, 2004, p. 124-128.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Höft, S, Maune, S, Muhle, C, Brenner, W, Czech, N, Kampen, W-U, Jänig, U, Laudien, M, Gottschlich, S & Ambrosch, P 2004, 'Sentinel lymph-node biopsy in head and neck cancer.', BRIT J CANCER, vol. 91, no. 1, 1, pp. 124-128. <http://www.ncbi.nlm.nih.gov/pubmed/15188012?dopt=Citation>

APA

Höft, S., Maune, S., Muhle, C., Brenner, W., Czech, N., Kampen, W-U., Jänig, U., Laudien, M., Gottschlich, S., & Ambrosch, P. (2004). Sentinel lymph-node biopsy in head and neck cancer. BRIT J CANCER, 91(1), 124-128. [1]. http://www.ncbi.nlm.nih.gov/pubmed/15188012?dopt=Citation

Vancouver

Höft S, Maune S, Muhle C, Brenner W, Czech N, Kampen W-U et al. Sentinel lymph-node biopsy in head and neck cancer. BRIT J CANCER. 2004;91(1):124-128. 1.

Bibtex

@article{2cd853acda2143329cd43e6513414800,
title = "Sentinel lymph-node biopsy in head and neck cancer.",
abstract = "The aim of the study was to assess the diagnostic value of the sentinel node method in patients suffering from squamous cell carcinoma of the upper aerodigestive tract. In 50 patients with oral, pharyngeal or laryngeal carcinomas staged N0 up to 50 MBq technetium-99m colloid were injected peritumorally. Sentinel nodes were localised using a gamma-probe in the setting of an elective neck dissection. Pathological findings of sentinel nodes and corresponding neck specimens were compared. In 46 patients sentinel nodes were detected. Of these 34 patients were free of metastatic disease in the sentinel nodes and in the neck specimens. In 12 patients clinically occult metastases were found in the sentinel nodes. Three metastases were detected only after additional sectioning of the sentinel nodes. In four patients, a sentinel lymph node could not be localised. Our results support the sentinel node concept in head and neck cancer and a definition of the sentinel nodes as the three nodes with the highest activity. Careful clinical staging of the neck and thorough pathological evaluation of the sentinel nodes are necessary to avoid false-negative results.",
author = "S H{\"o}ft and S Maune and C Muhle and Winfried Brenner and N Czech and W-U Kampen and U J{\"a}nig and M Laudien and S Gottschlich and P Ambrosch",
year = "2004",
language = "Deutsch",
volume = "91",
pages = "124--128",
journal = "BRIT J CANCER",
issn = "0007-0920",
publisher = "NATURE PUBLISHING GROUP",
number = "1",

}

RIS

TY - JOUR

T1 - Sentinel lymph-node biopsy in head and neck cancer.

AU - Höft, S

AU - Maune, S

AU - Muhle, C

AU - Brenner, Winfried

AU - Czech, N

AU - Kampen, W-U

AU - Jänig, U

AU - Laudien, M

AU - Gottschlich, S

AU - Ambrosch, P

PY - 2004

Y1 - 2004

N2 - The aim of the study was to assess the diagnostic value of the sentinel node method in patients suffering from squamous cell carcinoma of the upper aerodigestive tract. In 50 patients with oral, pharyngeal or laryngeal carcinomas staged N0 up to 50 MBq technetium-99m colloid were injected peritumorally. Sentinel nodes were localised using a gamma-probe in the setting of an elective neck dissection. Pathological findings of sentinel nodes and corresponding neck specimens were compared. In 46 patients sentinel nodes were detected. Of these 34 patients were free of metastatic disease in the sentinel nodes and in the neck specimens. In 12 patients clinically occult metastases were found in the sentinel nodes. Three metastases were detected only after additional sectioning of the sentinel nodes. In four patients, a sentinel lymph node could not be localised. Our results support the sentinel node concept in head and neck cancer and a definition of the sentinel nodes as the three nodes with the highest activity. Careful clinical staging of the neck and thorough pathological evaluation of the sentinel nodes are necessary to avoid false-negative results.

AB - The aim of the study was to assess the diagnostic value of the sentinel node method in patients suffering from squamous cell carcinoma of the upper aerodigestive tract. In 50 patients with oral, pharyngeal or laryngeal carcinomas staged N0 up to 50 MBq technetium-99m colloid were injected peritumorally. Sentinel nodes were localised using a gamma-probe in the setting of an elective neck dissection. Pathological findings of sentinel nodes and corresponding neck specimens were compared. In 46 patients sentinel nodes were detected. Of these 34 patients were free of metastatic disease in the sentinel nodes and in the neck specimens. In 12 patients clinically occult metastases were found in the sentinel nodes. Three metastases were detected only after additional sectioning of the sentinel nodes. In four patients, a sentinel lymph node could not be localised. Our results support the sentinel node concept in head and neck cancer and a definition of the sentinel nodes as the three nodes with the highest activity. Careful clinical staging of the neck and thorough pathological evaluation of the sentinel nodes are necessary to avoid false-negative results.

M3 - SCORING: Zeitschriftenaufsatz

VL - 91

SP - 124

EP - 128

JO - BRIT J CANCER

JF - BRIT J CANCER

SN - 0007-0920

IS - 1

M1 - 1

ER -