Selective late steroid withdrawal after renal transplantation.

Guido F Laube; Jutta Falger; Markus J. Kemper; Andrea Zingg-Schenk; Thomas J Neuhaus

Selective late steroid withdrawal after renal transplantation.

Standard

Selective late steroid withdrawal after renal transplantation. / Laube, Guido F; Falger, Jutta; Kemper, Markus J.; Zingg-Schenk, Andrea; Neuhaus, Thomas J.

In: PEDIATR NEPHROL, Vol. 22, No. 11, 11, 2007, p. 1947-1952.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Laube, GF, Falger, J, Kemper, MJ, Zingg-Schenk, A & Neuhaus, TJ 2007, 'Selective late steroid withdrawal after renal transplantation.', PEDIATR NEPHROL, vol. 22, no. 11, 11, pp. 1947-1952. <http://www.ncbi.nlm.nih.gov/pubmed/17874140?dopt=Citation>

APA

Laube, G. F., Falger, J., Kemper, M. J., Zingg-Schenk, A., & Neuhaus, T. J. (2007). Selective late steroid withdrawal after renal transplantation. PEDIATR NEPHROL, 22(11), 1947-1952. [11]. http://www.ncbi.nlm.nih.gov/pubmed/17874140?dopt=Citation

Vancouver

Laube GF, Falger J, Kemper MJ, Zingg-Schenk A, Neuhaus TJ. Selective late steroid withdrawal after renal transplantation. PEDIATR NEPHROL. 2007;22(11):1947-1952. 11.

Bibtex

@article{a3038c18d1de4497baa0f3cfa2ebe34a,

title = "Selective late steroid withdrawal after renal transplantation.",

abstract = "Steroid withdrawal (SW) after paediatric renal transplantation (RTPL) is controversial. Selective late SW has been performed in our unit since 1995. The safety and effects of SW were analysed retrospectively in 47 patients undergoing RTPL between 1995 and 2004. Initial immunosuppression consisted of cyclosporine A, azathioprine or mycophenolate mofetil and steroids. Criteria for SW were: (1) stable renal function, (2) time interval after RTPL > or = 1 year, (3) no rejection or time interval after last rejection > or = 1 year and (4) good compliance. SW was performed in 30 patients at an age of 13.5 years (range 4.5-18.5) and 2.2 years (range 1-6.6) after RTPL. After SW, one patient experienced a steroid-sensitive rejection. Follow-up after SW (1.3 year; range 0.25-7.5) showed maintained renal function: glomerular filtration rate at SW and currently was 82 (65-128) and 82 (42-115) ml/min per 1.73 m(2), respectively. The number of patients on antihypertensive treatment did not significantly change (at SW: n = 15; currently: n = 11). Height and body mass index (BMI) remained stable: Median standard deviation score (SDS) for height/BMI at SW and currently was -1.1/0.2 and -0.8/0.1, respectively. Selective late SW was safe regarding renal function and had no significant effect on blood pressure and growth.",

author = "Laube, {Guido F} and Jutta Falger and Kemper, {Markus J.} and Andrea Zingg-Schenk and Neuhaus, {Thomas J}",

year = "2007",

language = "Deutsch",

volume = "22",

pages = "1947--1952",

journal = "PEDIATR NEPHROL",

issn = "0931-041X",

publisher = "Springer",

number = "11",

}

RIS

TY - JOUR

T1 - Selective late steroid withdrawal after renal transplantation.

AU - Laube, Guido F

AU - Falger, Jutta

AU - Kemper, Markus J.

AU - Zingg-Schenk, Andrea

AU - Neuhaus, Thomas J

PY - 2007

Y1 - 2007

N2 - Steroid withdrawal (SW) after paediatric renal transplantation (RTPL) is controversial. Selective late SW has been performed in our unit since 1995. The safety and effects of SW were analysed retrospectively in 47 patients undergoing RTPL between 1995 and 2004. Initial immunosuppression consisted of cyclosporine A, azathioprine or mycophenolate mofetil and steroids. Criteria for SW were: (1) stable renal function, (2) time interval after RTPL > or = 1 year, (3) no rejection or time interval after last rejection > or = 1 year and (4) good compliance. SW was performed in 30 patients at an age of 13.5 years (range 4.5-18.5) and 2.2 years (range 1-6.6) after RTPL. After SW, one patient experienced a steroid-sensitive rejection. Follow-up after SW (1.3 year; range 0.25-7.5) showed maintained renal function: glomerular filtration rate at SW and currently was 82 (65-128) and 82 (42-115) ml/min per 1.73 m(2), respectively. The number of patients on antihypertensive treatment did not significantly change (at SW: n = 15; currently: n = 11). Height and body mass index (BMI) remained stable: Median standard deviation score (SDS) for height/BMI at SW and currently was -1.1/0.2 and -0.8/0.1, respectively. Selective late SW was safe regarding renal function and had no significant effect on blood pressure and growth.

AB - Steroid withdrawal (SW) after paediatric renal transplantation (RTPL) is controversial. Selective late SW has been performed in our unit since 1995. The safety and effects of SW were analysed retrospectively in 47 patients undergoing RTPL between 1995 and 2004. Initial immunosuppression consisted of cyclosporine A, azathioprine or mycophenolate mofetil and steroids. Criteria for SW were: (1) stable renal function, (2) time interval after RTPL > or = 1 year, (3) no rejection or time interval after last rejection > or = 1 year and (4) good compliance. SW was performed in 30 patients at an age of 13.5 years (range 4.5-18.5) and 2.2 years (range 1-6.6) after RTPL. After SW, one patient experienced a steroid-sensitive rejection. Follow-up after SW (1.3 year; range 0.25-7.5) showed maintained renal function: glomerular filtration rate at SW and currently was 82 (65-128) and 82 (42-115) ml/min per 1.73 m(2), respectively. The number of patients on antihypertensive treatment did not significantly change (at SW: n = 15; currently: n = 11). Height and body mass index (BMI) remained stable: Median standard deviation score (SDS) for height/BMI at SW and currently was -1.1/0.2 and -0.8/0.1, respectively. Selective late SW was safe regarding renal function and had no significant effect on blood pressure and growth.

M3 - SCORING: Zeitschriftenaufsatz

VL - 22

SP - 1947

EP - 1952

JO - PEDIATR NEPHROL

JF - PEDIATR NEPHROL

SN - 0931-041X

IS - 11

M1 - 11

ER -