Selective arterial spin labeling in conjunction with phase-contrast acquisition for the simultaneous visualization of morphology, flow direction, and velocity of individual arteries in the cerebrovascular system
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Selective arterial spin labeling in conjunction with phase-contrast acquisition for the simultaneous visualization of morphology, flow direction, and velocity of individual arteries in the cerebrovascular system. / Lindner, Thomas; Larsen, Naomi; Jansen, Olav; Helle, Michael.
In: MAGN RESON MED, Vol. 78, No. 4, 10.2017, p. 1469-1475.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Selective arterial spin labeling in conjunction with phase-contrast acquisition for the simultaneous visualization of morphology, flow direction, and velocity of individual arteries in the cerebrovascular system
AU - Lindner, Thomas
AU - Larsen, Naomi
AU - Jansen, Olav
AU - Helle, Michael
N1 - © 2016 International Society for Magnetic Resonance in Medicine.
PY - 2017/10
Y1 - 2017/10
N2 - PURPOSE: In various cerebrovascular diseases the visualization of individual arteries and knowledge about their hemodynamic properties, like flow velocity and direction, can become important for an accurate diagnosis. Magnetic resonance angiography methods are intended to acquire this information, but often a single acquisition is not sufficient to retrieve all of this desired information.METHODS: Using selective arterial spin labeling (ASL) methods, a single artery of interest can be tagged and visualized, whereas quantitative information about hemodynamics can be retrieved using phase-contrast techniques that are often limited regarding their selectivity. In this study, a method that allows for velocity mapping of individual arteries by incorporating phase-contrast preparation into selective ASL angiography measurements is presented. Several postprocessing steps are required to generate velocity and directional-encoded maps of selected arteries from the data acquired in a single scan.RESULTS: The method was successfully evaluated in healthy volunteers, and a first application in two selected patients is presented. In one patient, an aneurysm of the middle cerebral artery is investigated, and in the second patient it is used to visualize an arterio-venous malformation.CONCLUSION: Selective ASL imaging in conjunction with phase-contrast acquisition allows for investigating hemodynamic properties of individual arteries. Magn Reson Med 78:1469-1475, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
AB - PURPOSE: In various cerebrovascular diseases the visualization of individual arteries and knowledge about their hemodynamic properties, like flow velocity and direction, can become important for an accurate diagnosis. Magnetic resonance angiography methods are intended to acquire this information, but often a single acquisition is not sufficient to retrieve all of this desired information.METHODS: Using selective arterial spin labeling (ASL) methods, a single artery of interest can be tagged and visualized, whereas quantitative information about hemodynamics can be retrieved using phase-contrast techniques that are often limited regarding their selectivity. In this study, a method that allows for velocity mapping of individual arteries by incorporating phase-contrast preparation into selective ASL angiography measurements is presented. Several postprocessing steps are required to generate velocity and directional-encoded maps of selected arteries from the data acquired in a single scan.RESULTS: The method was successfully evaluated in healthy volunteers, and a first application in two selected patients is presented. In one patient, an aneurysm of the middle cerebral artery is investigated, and in the second patient it is used to visualize an arterio-venous malformation.CONCLUSION: Selective ASL imaging in conjunction with phase-contrast acquisition allows for investigating hemodynamic properties of individual arteries. Magn Reson Med 78:1469-1475, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
KW - Adult
KW - Blood Flow Velocity/physiology
KW - Cerebral Arteries/diagnostic imaging
KW - Cerebrovascular Circulation/physiology
KW - Female
KW - Humans
KW - Magnetic Resonance Angiography/methods
KW - Male
KW - Middle Aged
U2 - 10.1002/mrm.26542
DO - 10.1002/mrm.26542
M3 - SCORING: Journal article
C2 - 27797413
VL - 78
SP - 1469
EP - 1475
JO - MAGN RESON MED
JF - MAGN RESON MED
SN - 0740-3194
IS - 4
ER -
