Secretory Meningiomas: Characteristic Features and Clinical Management of a Unique Subgroup
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Secretory Meningiomas: Characteristic Features and Clinical Management of a Unique Subgroup. / Mohme, Malte; Emami, Pedram; Matschke, Jakob; Regelsberger, Jan; Westphal, Manfred; Eicker, Sven Oliver.
In: NEUROSURG CLIN N AM, Vol. 27, No. 2, 04.2016, p. 181-7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Secretory Meningiomas: Characteristic Features and Clinical Management of a Unique Subgroup
AU - Mohme, Malte
AU - Emami, Pedram
AU - Matschke, Jakob
AU - Regelsberger, Jan
AU - Westphal, Manfred
AU - Eicker, Sven Oliver
N1 - Copyright © 2016 Elsevier Inc. All rights reserved.
PY - 2016/4
Y1 - 2016/4
N2 - Secretory meningiomas (SM) represent a rare variant of the most common benign intracranial brain tumor. Defined by the histologic appearance of eosinophilic glandular formations and periodic-acidic Schiff-positive pseudopsammoma bodies, SM are characterized by unique molecular alterations, a disproportional occurrence of reactive peritumoral brain edema, and a clinical course that demands for increased awareness for perioperative complications. The frequent presence of extensive peritumoral edema has become a hallmark of SM and can be associated with life-threatening complications. The exact pathophysiology of edema formation in SM is still unknown.
AB - Secretory meningiomas (SM) represent a rare variant of the most common benign intracranial brain tumor. Defined by the histologic appearance of eosinophilic glandular formations and periodic-acidic Schiff-positive pseudopsammoma bodies, SM are characterized by unique molecular alterations, a disproportional occurrence of reactive peritumoral brain edema, and a clinical course that demands for increased awareness for perioperative complications. The frequent presence of extensive peritumoral edema has become a hallmark of SM and can be associated with life-threatening complications. The exact pathophysiology of edema formation in SM is still unknown.
U2 - 10.1016/j.nec.2015.11.001
DO - 10.1016/j.nec.2015.11.001
M3 - SCORING: Journal article
C2 - 27012382
VL - 27
SP - 181
EP - 187
JO - NEUROSURG CLIN N AM
JF - NEUROSURG CLIN N AM
SN - 1042-3680
IS - 2
ER -