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Safety and Efficacy of Aneurysm Treatment with the WEB: Results of the WEBCAST 2 Study

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Safety and Efficacy of Aneurysm Treatment with the WEB: Results of the WEBCAST 2 Study. / Pierot, L; Gubucz, I; Buhk, J H; Holtmannspötter, M; Herbreteau, D; Stockx, L; Spelle, L; Berkefeld, J; Januel, A-C; Molyneux, A; Byrne, J V; Fiehler, J; Szikora, I; Barreau, X.

In: AM J NEURORADIOL, Vol. 38, No. 6, 06.2017, p. 1151-1155.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Pierot, L, Gubucz, I, Buhk, JH, Holtmannspötter, M, Herbreteau, D, Stockx, L, Spelle, L, Berkefeld, J, Januel, A-C, Molyneux, A, Byrne, JV, Fiehler, J, Szikora, I & Barreau, X 2017, 'Safety and Efficacy of Aneurysm Treatment with the WEB: Results of the WEBCAST 2 Study', AM J NEURORADIOL, vol. 38, no. 6, pp. 1151-1155. https://doi.org/10.3174/ajnr.A5178

APA

Pierot, L., Gubucz, I., Buhk, J. H., Holtmannspötter, M., Herbreteau, D., Stockx, L., Spelle, L., Berkefeld, J., Januel, A-C., Molyneux, A., Byrne, J. V., Fiehler, J., Szikora, I., & Barreau, X. (2017). Safety and Efficacy of Aneurysm Treatment with the WEB: Results of the WEBCAST 2 Study. AM J NEURORADIOL, 38(6), 1151-1155. https://doi.org/10.3174/ajnr.A5178

Vancouver

Pierot L, Gubucz I, Buhk JH, Holtmannspötter M, Herbreteau D, Stockx L et al. Safety and Efficacy of Aneurysm Treatment with the WEB: Results of the WEBCAST 2 Study. AM J NEURORADIOL. 2017 Jun;38(6):1151-1155. https://doi.org/10.3174/ajnr.A5178

Bibtex

@article{7f8612fc5d7b491faac0e0360d6b0f6f,
title = "Safety and Efficacy of Aneurysm Treatment with the WEB: Results of the WEBCAST 2 Study",
abstract = "BACKGROUND AND PURPOSE: Flow disruption with the Woven EndoBridge (WEB) device is an innovative technique for the endovascular treatment of wide-neck bifurcation aneurysms. The initial version of the device (WEB Double-Layer) was evaluated in the WEB Clinical Assessment of IntraSaccular Aneurysm Therapy (WEBCAST) study, whereas the French Observatory study evaluated both WEB Double-Layer and Single-Layer versions of the device. WEBCAST 2 was designed to evaluate the WEB Single-Layer with Enhanced Visualization.MATERIALS AND METHODS: Patients with wide-neck bifurcation aneurysms for which WEB treatment was possible were included. Clinical data including adverse events and clinical status at 1 month and 1 year were collected and analyzed. A core laboratory evaluated anatomic results at 1 year following the procedure.RESULTS: Ten European neurointerventional centers included 55 patients (38 women; 27-77 years of age; mean, 54.4 ± 10.0 years) with 55 aneurysms. Aneurysm locations were the middle cerebral artery in 25 aneurysms (45.5%), the anterior communicating artery in 16 (29.1%), the basilar artery in 9 (16.4%), and the internal carotid artery terminus in 5 (9.1%). Procedural morbidity and mortality at 1 month were, respectively, 1.8% (1/55 patients) and 0.0% (0/55 patients). Morbidity and mortality at 1 year were, respectively, 3.9% (2/51 patients) and 2.0% (1/51 patients). At 1 year, complete occlusion was observed in 27/50 aneurysms (54.0%); neck remnant, in 13/50 (26.0%); and aneurysm remnant, in 10/50 (20.0%) (adequate occlusion in 40/50, 80.0%).CONCLUSIONS: WEBCAST 2 confirms the high safety and efficacy of WEB aneurysm treatment demonstrated in the WEBCAST and French Observatory studies.",
keywords = "Journal Article",
author = "L Pierot and I Gubucz and Buhk, {J H} and M Holtmannsp{\"o}tter and D Herbreteau and L Stockx and L Spelle and J Berkefeld and A-C Januel and A Molyneux and Byrne, {J V} and J Fiehler and I Szikora and X Barreau",
note = "{\textcopyright} 2017 by American Journal of Neuroradiology.",
year = "2017",
month = jun,
doi = "10.3174/ajnr.A5178",
language = "English",
volume = "38",
pages = "1151--1155",
journal = "AM J NEURORADIOL",
issn = "0195-6108",
publisher = "American Society of Neuroradiology",
number = "6",

}

RIS

TY - JOUR

T1 - Safety and Efficacy of Aneurysm Treatment with the WEB: Results of the WEBCAST 2 Study

AU - Pierot, L

AU - Gubucz, I

AU - Buhk, J H

AU - Holtmannspötter, M

AU - Herbreteau, D

AU - Stockx, L

AU - Spelle, L

AU - Berkefeld, J

AU - Januel, A-C

AU - Molyneux, A

AU - Byrne, J V

AU - Fiehler, J

AU - Szikora, I

AU - Barreau, X

N1 - © 2017 by American Journal of Neuroradiology.

PY - 2017/6

Y1 - 2017/6

N2 - BACKGROUND AND PURPOSE: Flow disruption with the Woven EndoBridge (WEB) device is an innovative technique for the endovascular treatment of wide-neck bifurcation aneurysms. The initial version of the device (WEB Double-Layer) was evaluated in the WEB Clinical Assessment of IntraSaccular Aneurysm Therapy (WEBCAST) study, whereas the French Observatory study evaluated both WEB Double-Layer and Single-Layer versions of the device. WEBCAST 2 was designed to evaluate the WEB Single-Layer with Enhanced Visualization.MATERIALS AND METHODS: Patients with wide-neck bifurcation aneurysms for which WEB treatment was possible were included. Clinical data including adverse events and clinical status at 1 month and 1 year were collected and analyzed. A core laboratory evaluated anatomic results at 1 year following the procedure.RESULTS: Ten European neurointerventional centers included 55 patients (38 women; 27-77 years of age; mean, 54.4 ± 10.0 years) with 55 aneurysms. Aneurysm locations were the middle cerebral artery in 25 aneurysms (45.5%), the anterior communicating artery in 16 (29.1%), the basilar artery in 9 (16.4%), and the internal carotid artery terminus in 5 (9.1%). Procedural morbidity and mortality at 1 month were, respectively, 1.8% (1/55 patients) and 0.0% (0/55 patients). Morbidity and mortality at 1 year were, respectively, 3.9% (2/51 patients) and 2.0% (1/51 patients). At 1 year, complete occlusion was observed in 27/50 aneurysms (54.0%); neck remnant, in 13/50 (26.0%); and aneurysm remnant, in 10/50 (20.0%) (adequate occlusion in 40/50, 80.0%).CONCLUSIONS: WEBCAST 2 confirms the high safety and efficacy of WEB aneurysm treatment demonstrated in the WEBCAST and French Observatory studies.

AB - BACKGROUND AND PURPOSE: Flow disruption with the Woven EndoBridge (WEB) device is an innovative technique for the endovascular treatment of wide-neck bifurcation aneurysms. The initial version of the device (WEB Double-Layer) was evaluated in the WEB Clinical Assessment of IntraSaccular Aneurysm Therapy (WEBCAST) study, whereas the French Observatory study evaluated both WEB Double-Layer and Single-Layer versions of the device. WEBCAST 2 was designed to evaluate the WEB Single-Layer with Enhanced Visualization.MATERIALS AND METHODS: Patients with wide-neck bifurcation aneurysms for which WEB treatment was possible were included. Clinical data including adverse events and clinical status at 1 month and 1 year were collected and analyzed. A core laboratory evaluated anatomic results at 1 year following the procedure.RESULTS: Ten European neurointerventional centers included 55 patients (38 women; 27-77 years of age; mean, 54.4 ± 10.0 years) with 55 aneurysms. Aneurysm locations were the middle cerebral artery in 25 aneurysms (45.5%), the anterior communicating artery in 16 (29.1%), the basilar artery in 9 (16.4%), and the internal carotid artery terminus in 5 (9.1%). Procedural morbidity and mortality at 1 month were, respectively, 1.8% (1/55 patients) and 0.0% (0/55 patients). Morbidity and mortality at 1 year were, respectively, 3.9% (2/51 patients) and 2.0% (1/51 patients). At 1 year, complete occlusion was observed in 27/50 aneurysms (54.0%); neck remnant, in 13/50 (26.0%); and aneurysm remnant, in 10/50 (20.0%) (adequate occlusion in 40/50, 80.0%).CONCLUSIONS: WEBCAST 2 confirms the high safety and efficacy of WEB aneurysm treatment demonstrated in the WEBCAST and French Observatory studies.

KW - Journal Article

U2 - 10.3174/ajnr.A5178

DO - 10.3174/ajnr.A5178

M3 - SCORING: Journal article

C2 - 28450432

VL - 38

SP - 1151

EP - 1155

JO - AM J NEURORADIOL

JF - AM J NEURORADIOL

SN - 0195-6108

IS - 6

ER -