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Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser-A prospective, controlled study

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Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser-A prospective, controlled study. / Nguyen, Lynhda; Dierckxsens, Cathy; Kerscher, Martina; Hartjen, Anna; Schneider, Stefan W; Herberger, Katharina.

In: J COSMET DERMATOL-US, Vol. 23, No. 7, 07.2024, p. 2443-2449.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Nguyen, L, Dierckxsens, C, Kerscher, M, Hartjen, A, Schneider, SW & Herberger, K 2024, 'Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser-A prospective, controlled study', J COSMET DERMATOL-US, vol. 23, no. 7, pp. 2443-2449. https://doi.org/10.1111/jocd.16300

APA

Nguyen, L., Dierckxsens, C., Kerscher, M., Hartjen, A., Schneider, S. W., & Herberger, K. (2024). Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser-A prospective, controlled study. J COSMET DERMATOL-US, 23(7), 2443-2449. https://doi.org/10.1111/jocd.16300

Vancouver

Nguyen L, Dierckxsens C, Kerscher M, Hartjen A, Schneider SW, Herberger K. Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser-A prospective, controlled study. J COSMET DERMATOL-US. 2024 Jul;23(7):2443-2449. https://doi.org/10.1111/jocd.16300

Bibtex

@article{119922a204284f7d8f09b439329a0a4b,
title = "Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser-A prospective, controlled study",
abstract = "BACKGROUND: Pulsed-dye lasers (PDL) are one of the standard therapies for rosacea, but alternatives are needed.AIMS: To compare the efficacy and safety of the variable-sequenced, large-spot 532 nm KTP laser to the 595 nm PDL in treating rosacea.MATERIALS AND METHODS: A prospective, controlled, evaluator-blinded study. Patients were treated with either a KTP or PDL with 1-3 sessions at intervals of 6-8 weeks. A follow-up visit was scheduled on Week 6 post-treatment. Clinical outcome was assessed by computer-assisted analysis and by patients and two blinded dermatologists. Pain intensity during treatment and adverse events were documented.RESULTS: Forty-five patients (mean age 51 years) were allocated in a 2:1 ratio to either the KTP or PDL. Erythema in both treatment arms decreased significantly (p < 0.01). Clinical evaluation revealed high improvement. Mean pain intensity was significantly lower with the KTP (2.5/10) than with the PDL (4.1/10). Both lasers showed a good safety profile. Relevant purpura was only seen in the PDL group.CONCLUSIONS: Both the variable-sequenced, large-spot KTP and the PDL demonstrated comparable efficacy in treatment of rosacea. Regarding safety, the KTP exhibited fewer post-treatment reactions. The KTP might serve as a potential alternative to PDL in the treatment of rosacea.",
keywords = "Adult, Aged, Female, Humans, Male, Middle Aged, Erythema/etiology, Lasers, Dye/therapeutic use, Lasers, Solid-State/therapeutic use, Low-Level Light Therapy/adverse effects, Pain Measurement, Prospective Studies, Purpura/etiology, Rosacea/therapy, Single-Blind Method, Treatment Outcome",
author = "Lynhda Nguyen and Cathy Dierckxsens and Martina Kerscher and Anna Hartjen and Schneider, {Stefan W} and Katharina Herberger",
note = "{\textcopyright} 2024 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.",
year = "2024",
month = jul,
doi = "10.1111/jocd.16300",
language = "English",
volume = "23",
pages = "2443--2449",
journal = "J COSMET DERMATOL-US",
issn = "1473-2130",
publisher = "Wiley-Blackwell",
number = "7",

}

RIS

TY - JOUR

T1 - Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser-A prospective, controlled study

AU - Nguyen, Lynhda

AU - Dierckxsens, Cathy

AU - Kerscher, Martina

AU - Hartjen, Anna

AU - Schneider, Stefan W

AU - Herberger, Katharina

N1 - © 2024 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.

PY - 2024/7

Y1 - 2024/7

N2 - BACKGROUND: Pulsed-dye lasers (PDL) are one of the standard therapies for rosacea, but alternatives are needed.AIMS: To compare the efficacy and safety of the variable-sequenced, large-spot 532 nm KTP laser to the 595 nm PDL in treating rosacea.MATERIALS AND METHODS: A prospective, controlled, evaluator-blinded study. Patients were treated with either a KTP or PDL with 1-3 sessions at intervals of 6-8 weeks. A follow-up visit was scheduled on Week 6 post-treatment. Clinical outcome was assessed by computer-assisted analysis and by patients and two blinded dermatologists. Pain intensity during treatment and adverse events were documented.RESULTS: Forty-five patients (mean age 51 years) were allocated in a 2:1 ratio to either the KTP or PDL. Erythema in both treatment arms decreased significantly (p < 0.01). Clinical evaluation revealed high improvement. Mean pain intensity was significantly lower with the KTP (2.5/10) than with the PDL (4.1/10). Both lasers showed a good safety profile. Relevant purpura was only seen in the PDL group.CONCLUSIONS: Both the variable-sequenced, large-spot KTP and the PDL demonstrated comparable efficacy in treatment of rosacea. Regarding safety, the KTP exhibited fewer post-treatment reactions. The KTP might serve as a potential alternative to PDL in the treatment of rosacea.

AB - BACKGROUND: Pulsed-dye lasers (PDL) are one of the standard therapies for rosacea, but alternatives are needed.AIMS: To compare the efficacy and safety of the variable-sequenced, large-spot 532 nm KTP laser to the 595 nm PDL in treating rosacea.MATERIALS AND METHODS: A prospective, controlled, evaluator-blinded study. Patients were treated with either a KTP or PDL with 1-3 sessions at intervals of 6-8 weeks. A follow-up visit was scheduled on Week 6 post-treatment. Clinical outcome was assessed by computer-assisted analysis and by patients and two blinded dermatologists. Pain intensity during treatment and adverse events were documented.RESULTS: Forty-five patients (mean age 51 years) were allocated in a 2:1 ratio to either the KTP or PDL. Erythema in both treatment arms decreased significantly (p < 0.01). Clinical evaluation revealed high improvement. Mean pain intensity was significantly lower with the KTP (2.5/10) than with the PDL (4.1/10). Both lasers showed a good safety profile. Relevant purpura was only seen in the PDL group.CONCLUSIONS: Both the variable-sequenced, large-spot KTP and the PDL demonstrated comparable efficacy in treatment of rosacea. Regarding safety, the KTP exhibited fewer post-treatment reactions. The KTP might serve as a potential alternative to PDL in the treatment of rosacea.

KW - Adult

KW - Aged

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Erythema/etiology

KW - Lasers, Dye/therapeutic use

KW - Lasers, Solid-State/therapeutic use

KW - Low-Level Light Therapy/adverse effects

KW - Pain Measurement

KW - Prospective Studies

KW - Purpura/etiology

KW - Rosacea/therapy

KW - Single-Blind Method

KW - Treatment Outcome

U2 - 10.1111/jocd.16300

DO - 10.1111/jocd.16300

M3 - SCORING: Journal article

C2 - 38600654

VL - 23

SP - 2443

EP - 2449

JO - J COSMET DERMATOL-US

JF - J COSMET DERMATOL-US

SN - 1473-2130

IS - 7

ER -