Room-temperature vs iced saline indicator injection for transpulmonary thermodilution

Wolfgang Huber; Thilo Kraski; Bernhard Haller; Sebastian Mair; Bernd Saugel; Analena Beitz; Roland M Schmid; Manu L N G Malbrain

doi:10.1016/j.jcrc.2014.08.005

Room-temperature vs iced saline indicator injection for transpulmonary thermodilution

Standard

Room-temperature vs iced saline indicator injection for transpulmonary thermodilution. / Huber, Wolfgang; Kraski, Thilo; Haller, Bernhard; Mair, Sebastian; Saugel, Bernd; Beitz, Analena; Schmid, Roland M; Malbrain, Manu L N G.

In: J CRIT CARE, Vol. 29, No. 6, 01.12.2014, p. 1133.e7-1133.e14.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Huber, W, Kraski, T, Haller, B, Mair, S, Saugel, B, Beitz, A, Schmid, RM & Malbrain, MLNG 2014, 'Room-temperature vs iced saline indicator injection for transpulmonary thermodilution', J CRIT CARE, vol. 29, no. 6, pp. 1133.e7-1133.e14. https://doi.org/10.1016/j.jcrc.2014.08.005

APA

Huber, W., Kraski, T., Haller, B., Mair, S., Saugel, B., Beitz, A., Schmid, R. M., & Malbrain, M. L. N. G. (2014). Room-temperature vs iced saline indicator injection for transpulmonary thermodilution. J CRIT CARE, 29(6), 1133.e7-1133.e14. https://doi.org/10.1016/j.jcrc.2014.08.005

Vancouver

Huber W, Kraski T, Haller B, Mair S, Saugel B, Beitz A et al. Room-temperature vs iced saline indicator injection for transpulmonary thermodilution. J CRIT CARE. 2014 Dec 1;29(6):1133.e7-1133.e14. https://doi.org/10.1016/j.jcrc.2014.08.005

Bibtex

@article{1e2a6cac07dc456882da19fdb9ae8f9b,

title = "Room-temperature vs iced saline indicator injection for transpulmonary thermodilution",

abstract = "PURPOSE: Ice-cold injectate is assumed to provide best accuracy for transpulmonary thermodilution (TPTD)-derived cardiac index (CI), global end-diastolic volume index (GEDVI), and extravascular lung-water index (EVLWI). Room-temperature injectate might facilitate TPTD. Therefore, this study compares TPTD-results derived from iced injectate with room-temperature injectate TPTDs (TPTDRoom).MATERIALS AND METHODS: Forty-five adult intensive care unit patients with PiCCO monitoring (Pulsion Medical Systems, Munich, Germany) were included in this observational study. Four hundred one sets of TPTDs were recorded. Each set consisted of four 15 mL TPTDs (twice with 21°C and subsequently twice with 4°C saline). Means of 2 TPTDRoom were compared with means of 2 cold TPTDs (primary end point).RESULTS: Mean CI (4.70±1.60 vs 4.54±1.52 L/min per square meter; P<.001), GEDVI (985±294 vs 954±269 mL/m2; P<.001), and EVLWI (14.4±7.8 vs 13.8±7.3 mL/kg; P<.001) were significantly higher for TPTDRoom compared with TPTD-results derived from iced injectate. Mean bias and percentage error were 0.15±0.52 L/min per square meter and 21.9% for CI, 30±145 mL/m2 and 29.3% for GEDVI, and 0.59±2.1 mL/kg and 29.3% for EVLWI. Percentage error values were higher in case of femoral compared with jugular indicator injection for CI (25% vs 20%), GEDVI (35% vs 25%), and EVLWI (41% vs 23%).CONCLUSIONS: Room-temperature injectate TPTDs results in slight but significant overestimation of CI, GEDVI, and EVLWI. Percentage error values for GEDVIRoom and EVLWIRoom are acceptable only in case of {"}jugular{"} indicator injection.",

keywords = "Adult, Aged, Body Surface Area, Cardiac Output, Extravascular Lung Water, Female, Humans, Ice, Intensive Care Units, Male, Middle Aged, Sodium Chloride, Temperature, Thermodilution",

author = "Wolfgang Huber and Thilo Kraski and Bernhard Haller and Sebastian Mair and Bernd Saugel and Analena Beitz and Schmid, {Roland M} and Malbrain, {Manu L N G}",

year = "2014",

month = dec,

day = "1",

doi = "10.1016/j.jcrc.2014.08.005",

language = "English",

volume = "29",

pages = "1133.e7--1133.e14",

journal = "J CRIT CARE",

issn = "0883-9441",

publisher = "Elsevier BV",

number = "6",

}

RIS

TY - JOUR

T1 - Room-temperature vs iced saline indicator injection for transpulmonary thermodilution

AU - Huber, Wolfgang

AU - Kraski, Thilo

AU - Haller, Bernhard

AU - Mair, Sebastian

AU - Saugel, Bernd

AU - Beitz, Analena

AU - Schmid, Roland M

AU - Malbrain, Manu L N G

PY - 2014/12/1

Y1 - 2014/12/1

N2 - PURPOSE: Ice-cold injectate is assumed to provide best accuracy for transpulmonary thermodilution (TPTD)-derived cardiac index (CI), global end-diastolic volume index (GEDVI), and extravascular lung-water index (EVLWI). Room-temperature injectate might facilitate TPTD. Therefore, this study compares TPTD-results derived from iced injectate with room-temperature injectate TPTDs (TPTDRoom).MATERIALS AND METHODS: Forty-five adult intensive care unit patients with PiCCO monitoring (Pulsion Medical Systems, Munich, Germany) were included in this observational study. Four hundred one sets of TPTDs were recorded. Each set consisted of four 15 mL TPTDs (twice with 21°C and subsequently twice with 4°C saline). Means of 2 TPTDRoom were compared with means of 2 cold TPTDs (primary end point).RESULTS: Mean CI (4.70±1.60 vs 4.54±1.52 L/min per square meter; P<.001), GEDVI (985±294 vs 954±269 mL/m2; P<.001), and EVLWI (14.4±7.8 vs 13.8±7.3 mL/kg; P<.001) were significantly higher for TPTDRoom compared with TPTD-results derived from iced injectate. Mean bias and percentage error were 0.15±0.52 L/min per square meter and 21.9% for CI, 30±145 mL/m2 and 29.3% for GEDVI, and 0.59±2.1 mL/kg and 29.3% for EVLWI. Percentage error values were higher in case of femoral compared with jugular indicator injection for CI (25% vs 20%), GEDVI (35% vs 25%), and EVLWI (41% vs 23%).CONCLUSIONS: Room-temperature injectate TPTDs results in slight but significant overestimation of CI, GEDVI, and EVLWI. Percentage error values for GEDVIRoom and EVLWIRoom are acceptable only in case of "jugular" indicator injection.

AB - PURPOSE: Ice-cold injectate is assumed to provide best accuracy for transpulmonary thermodilution (TPTD)-derived cardiac index (CI), global end-diastolic volume index (GEDVI), and extravascular lung-water index (EVLWI). Room-temperature injectate might facilitate TPTD. Therefore, this study compares TPTD-results derived from iced injectate with room-temperature injectate TPTDs (TPTDRoom).MATERIALS AND METHODS: Forty-five adult intensive care unit patients with PiCCO monitoring (Pulsion Medical Systems, Munich, Germany) were included in this observational study. Four hundred one sets of TPTDs were recorded. Each set consisted of four 15 mL TPTDs (twice with 21°C and subsequently twice with 4°C saline). Means of 2 TPTDRoom were compared with means of 2 cold TPTDs (primary end point).RESULTS: Mean CI (4.70±1.60 vs 4.54±1.52 L/min per square meter; P<.001), GEDVI (985±294 vs 954±269 mL/m2; P<.001), and EVLWI (14.4±7.8 vs 13.8±7.3 mL/kg; P<.001) were significantly higher for TPTDRoom compared with TPTD-results derived from iced injectate. Mean bias and percentage error were 0.15±0.52 L/min per square meter and 21.9% for CI, 30±145 mL/m2 and 29.3% for GEDVI, and 0.59±2.1 mL/kg and 29.3% for EVLWI. Percentage error values were higher in case of femoral compared with jugular indicator injection for CI (25% vs 20%), GEDVI (35% vs 25%), and EVLWI (41% vs 23%).CONCLUSIONS: Room-temperature injectate TPTDs results in slight but significant overestimation of CI, GEDVI, and EVLWI. Percentage error values for GEDVIRoom and EVLWIRoom are acceptable only in case of "jugular" indicator injection.

KW - Adult

KW - Aged

KW - Body Surface Area

KW - Cardiac Output

KW - Extravascular Lung Water

KW - Female

KW - Humans

KW - Ice

KW - Intensive Care Units

KW - Male

KW - Middle Aged

KW - Sodium Chloride

KW - Temperature

KW - Thermodilution

U2 - 10.1016/j.jcrc.2014.08.005

DO - 10.1016/j.jcrc.2014.08.005

M3 - SCORING: Journal article

C2 - 25240464

VL - 29

SP - 1133.e7-1133.e14

JO - J CRIT CARE

JF - J CRIT CARE

SN - 0883-9441

IS - 6

ER -