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Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation

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Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation. / Meershoek, Philippa; van Oosterom, Matthias N; Simon, Hervé; Mengus, Laurent; Maurer, Tobias; van Leeuwen, Pim J; Wit, Esther M K; van der Poel, Henk G; van Leeuwen, Fijs W B.

In: EUR J NUCL MED MOL I, Vol. 46, No. 1, 01.2019, p. 49-53.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Meershoek, P, van Oosterom, MN, Simon, H, Mengus, L, Maurer, T, van Leeuwen, PJ, Wit, EMK, van der Poel, HG & van Leeuwen, FWB 2019, 'Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation', EUR J NUCL MED MOL I, vol. 46, no. 1, pp. 49-53. https://doi.org/10.1007/s00259-018-4095-z

APA

Meershoek, P., van Oosterom, M. N., Simon, H., Mengus, L., Maurer, T., van Leeuwen, P. J., Wit, E. M. K., van der Poel, H. G., & van Leeuwen, F. W. B. (2019). Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation. EUR J NUCL MED MOL I, 46(1), 49-53. https://doi.org/10.1007/s00259-018-4095-z

Vancouver

Meershoek P, van Oosterom MN, Simon H, Mengus L, Maurer T, van Leeuwen PJ et al. Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation. EUR J NUCL MED MOL I. 2019 Jan;46(1):49-53. https://doi.org/10.1007/s00259-018-4095-z

Bibtex

@article{3b87b0a7c4304ea6bcaf35b5dca8025c,
title = "Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation",
abstract = "PURPOSE: Radioguided surgery has been widely used for clinical procedures such as sentinel node resections. In the (robot-assisted) laparoscopic setting radioguidance is realized using laparoscopic gamma probes, which have limited maneuverability. To increase the rotational freedom, a tethered DROP-IN gamma probe was designed. Here we present the first in vivo feasibility study of this technology in prostate cancer patients.METHODS: Ten patients scheduled for a sentinel node procedure received four injections into the prostate with (indocyanine green-)99mTechnetium-nanocolloid and underwent preoperative imaging (lymphoscintigraphy and SPECT/CT). The DROP-IN probe was inserted via the assistant port, still permitting the insertion and usage of additional laparoscopic tools.RESULTS: The sentinel nodes were resected using the da Vinci{\textregistered} Si robot under guidance of DROP-IN gamma tracing and fluorescence imaging. The surgeon was able to independently maneuver the DROP-IN probe using the ProGrasp{\textregistered} forceps of the da Vinci{\textregistered} robot and distinguish sentinel nodes from background signal (such as the injection site).CONCLUSIONS: Overall the DROP-IN design proves to be a valuable tool for robot-assisted radioguided surgery approaches.",
keywords = "Aged, Humans, Indocyanine Green, Laparoscopy/instrumentation, Male, Middle Aged, Prostatic Neoplasms/diagnostic imaging, Radiopharmaceuticals, Robotic Surgical Procedures/instrumentation, Sentinel Lymph Node/surgery, Single Photon Emission Computed Tomography Computed Tomography, Technetium",
author = "Philippa Meershoek and {van Oosterom}, {Matthias N} and Herv{\'e} Simon and Laurent Mengus and Tobias Maurer and {van Leeuwen}, {Pim J} and Wit, {Esther M K} and {van der Poel}, {Henk G} and {van Leeuwen}, {Fijs W B}",
year = "2019",
month = jan,
doi = "10.1007/s00259-018-4095-z",
language = "English",
volume = "46",
pages = "49--53",
journal = "EUR J NUCL MED MOL I",
issn = "1619-7070",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation

AU - Meershoek, Philippa

AU - van Oosterom, Matthias N

AU - Simon, Hervé

AU - Mengus, Laurent

AU - Maurer, Tobias

AU - van Leeuwen, Pim J

AU - Wit, Esther M K

AU - van der Poel, Henk G

AU - van Leeuwen, Fijs W B

PY - 2019/1

Y1 - 2019/1

N2 - PURPOSE: Radioguided surgery has been widely used for clinical procedures such as sentinel node resections. In the (robot-assisted) laparoscopic setting radioguidance is realized using laparoscopic gamma probes, which have limited maneuverability. To increase the rotational freedom, a tethered DROP-IN gamma probe was designed. Here we present the first in vivo feasibility study of this technology in prostate cancer patients.METHODS: Ten patients scheduled for a sentinel node procedure received four injections into the prostate with (indocyanine green-)99mTechnetium-nanocolloid and underwent preoperative imaging (lymphoscintigraphy and SPECT/CT). The DROP-IN probe was inserted via the assistant port, still permitting the insertion and usage of additional laparoscopic tools.RESULTS: The sentinel nodes were resected using the da Vinci® Si robot under guidance of DROP-IN gamma tracing and fluorescence imaging. The surgeon was able to independently maneuver the DROP-IN probe using the ProGrasp® forceps of the da Vinci® robot and distinguish sentinel nodes from background signal (such as the injection site).CONCLUSIONS: Overall the DROP-IN design proves to be a valuable tool for robot-assisted radioguided surgery approaches.

AB - PURPOSE: Radioguided surgery has been widely used for clinical procedures such as sentinel node resections. In the (robot-assisted) laparoscopic setting radioguidance is realized using laparoscopic gamma probes, which have limited maneuverability. To increase the rotational freedom, a tethered DROP-IN gamma probe was designed. Here we present the first in vivo feasibility study of this technology in prostate cancer patients.METHODS: Ten patients scheduled for a sentinel node procedure received four injections into the prostate with (indocyanine green-)99mTechnetium-nanocolloid and underwent preoperative imaging (lymphoscintigraphy and SPECT/CT). The DROP-IN probe was inserted via the assistant port, still permitting the insertion and usage of additional laparoscopic tools.RESULTS: The sentinel nodes were resected using the da Vinci® Si robot under guidance of DROP-IN gamma tracing and fluorescence imaging. The surgeon was able to independently maneuver the DROP-IN probe using the ProGrasp® forceps of the da Vinci® robot and distinguish sentinel nodes from background signal (such as the injection site).CONCLUSIONS: Overall the DROP-IN design proves to be a valuable tool for robot-assisted radioguided surgery approaches.

KW - Aged

KW - Humans

KW - Indocyanine Green

KW - Laparoscopy/instrumentation

KW - Male

KW - Middle Aged

KW - Prostatic Neoplasms/diagnostic imaging

KW - Radiopharmaceuticals

KW - Robotic Surgical Procedures/instrumentation

KW - Sentinel Lymph Node/surgery

KW - Single Photon Emission Computed Tomography Computed Tomography

KW - Technetium

U2 - 10.1007/s00259-018-4095-z

DO - 10.1007/s00259-018-4095-z

M3 - SCORING: Journal article

C2 - 30054696

VL - 46

SP - 49

EP - 53

JO - EUR J NUCL MED MOL I

JF - EUR J NUCL MED MOL I

SN - 1619-7070

IS - 1

ER -