RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells.
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RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells. / von Bueren, André; André, O; Shalaby, Tarek; Oehler-Jänne, Christoph; Arnold, Lucia; Stearns, Duncan; Eberhart, Charles G; Arcaro, Alexandre; Pruschy, Martin; Grotzer, Michael A.
In: BMC CANCER, Vol. 9, 2009, p. 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells.
AU - von Bueren, André
AU - André, O
AU - Shalaby, Tarek
AU - Oehler-Jänne, Christoph
AU - Arnold, Lucia
AU - Stearns, Duncan
AU - Eberhart, Charles G
AU - Arcaro, Alexandre
AU - Pruschy, Martin
AU - Grotzer, Michael A
PY - 2009
Y1 - 2009
N2 - With current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident in numerous human cancers. In MB, over-expression of c-MYC has been shown to cause anaplasia and correlate with unfavorable prognosis.
AB - With current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident in numerous human cancers. In MB, over-expression of c-MYC has been shown to cause anaplasia and correlate with unfavorable prognosis.
M3 - SCORING: Zeitschriftenaufsatz
VL - 9
SP - 10
JO - BMC CANCER
JF - BMC CANCER
SN - 1471-2407
ER -