Risk factors for early death in children with haemophagocytic lymphohistiocytosis.

  • Helena Trottestam
  • Elisabet Berglöf
  • AnnaCarin Horne
  • Erik Onelöv
  • Karin Beutel
  • Kai Lehmberg
  • Elena Sieni
  • Thomas Silfverberg
  • Maurizio Aricò
  • Gritta Janka-Schaub
  • Jan-Inge Henter

Abstract

Haemophagocytic lymphohistiocytosis (HLH) is a life-threatening disturbance of immunoregulation. HLH comprises primary and acquired forms with different disease severity. A large proportion of deaths occur early into treatment. We investigated association with early death for laboratory and clinical parameters before the start of and 2 weeks into therapy.

Bibliographical data

Original languageEnglish
Article number3
ISSN0803-5253
Publication statusPublished - 2012
pubmed 22017632