Retroviral vectors pseudotyped with lymphocytic choriomeningitis virus.

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Abstract

Pseudotyping can improve retroviral vector stability and transduction efficiency. Here, we describe a novel pseudotype of murine leukemia virus packaged with lymphocytic choriomeningitis virus (LCMV). This pseudotype was stable during ultracentrifugation and infected several cell lines from different species. Moreover, LCMV glycoproteins were not cell toxic.

Bibliographical data

Original languageGerman
Article number7
ISSN0022-538X
Publication statusPublished - 1999
pubmed 10364368