Retrospective clinical case series study in 2017 identifies as most frequent species in returning travellers from Thailand to Germany
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Retrospective clinical case series study in 2017 identifies as most frequent species in returning travellers from Thailand to Germany. / Froeschl, Guenter; Nothdurft, Hans Dieter; von Sonnenburg, Frank; Bretzel, Gisela; Polanetz, Roman; Kroidl, Inge; Seilmaier, Michael; Orth, Hans Martin; Jordan, Sabine; Kremsner, Peter; Vygen-Bonnet, Sabine; Pritsch, Michael; Hoelscher, Michael; Rothe, Camilla.
In: EUROSURVEILLANCE, Vol. 23, No. 29, 07.2018, p. 14-20.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Retrospective clinical case series study in 2017 identifies as most frequent species in returning travellers from Thailand to Germany
AU - Froeschl, Guenter
AU - Nothdurft, Hans Dieter
AU - von Sonnenburg, Frank
AU - Bretzel, Gisela
AU - Polanetz, Roman
AU - Kroidl, Inge
AU - Seilmaier, Michael
AU - Orth, Hans Martin
AU - Jordan, Sabine
AU - Kremsner, Peter
AU - Vygen-Bonnet, Sabine
AU - Pritsch, Michael
AU - Hoelscher, Michael
AU - Rothe, Camilla
PY - 2018/7
Y1 - 2018/7
N2 - Febrile illnesses are common in travellers returning from south-east Asia. However, malaria is a rare diagnosis in this population. A series of Plasmodium knowlesi infections was noted in German travellers returning from Thailand since 2012. Infectious disease and tropical medicine facilities registered by the German Society for Tropical Medicine and International Health were contacted in March 2017, and asked to report previous P. knowlesi cases. In addition, surveillance data from the Robert Koch-Institute were analysed. The facilities reported a total of six P. knowlesi-positive cases, all were returning travellers from Thailand. The P. knowlesi-positive cases made up 6/9 of all diagnosed malaria cases imported from Thailand in the time period 2012 to 2017. In 4/5 of cases where a malaria rapid diagnostic test had been applied it revealed a negative result. P. knowlesi is an important differential diagnosis in travellers returning from south-east Asia with itineraries that include Thailand. This study highlights the importance of this Plasmodium species in this patient subgroup. Whenever malaria is suspected in a returning traveller from Thailand, P. knowlesi should be taken into consideration and a differential PCR be executed as currently the unequivocal diagnosis of P. knowlesi is based on nuclear amplification techniques.
AB - Febrile illnesses are common in travellers returning from south-east Asia. However, malaria is a rare diagnosis in this population. A series of Plasmodium knowlesi infections was noted in German travellers returning from Thailand since 2012. Infectious disease and tropical medicine facilities registered by the German Society for Tropical Medicine and International Health were contacted in March 2017, and asked to report previous P. knowlesi cases. In addition, surveillance data from the Robert Koch-Institute were analysed. The facilities reported a total of six P. knowlesi-positive cases, all were returning travellers from Thailand. The P. knowlesi-positive cases made up 6/9 of all diagnosed malaria cases imported from Thailand in the time period 2012 to 2017. In 4/5 of cases where a malaria rapid diagnostic test had been applied it revealed a negative result. P. knowlesi is an important differential diagnosis in travellers returning from south-east Asia with itineraries that include Thailand. This study highlights the importance of this Plasmodium species in this patient subgroup. Whenever malaria is suspected in a returning traveller from Thailand, P. knowlesi should be taken into consideration and a differential PCR be executed as currently the unequivocal diagnosis of P. knowlesi is based on nuclear amplification techniques.
KW - Journal Article
U2 - 10.2807/1560-7917.ES.2018.23.29.1700619
DO - 10.2807/1560-7917.ES.2018.23.29.1700619
M3 - SCORING: Journal article
C2 - 30043723
VL - 23
SP - 14
EP - 20
JO - EUROSURVEILLANCE
JF - EUROSURVEILLANCE
SN - 1025-496X
IS - 29
ER -