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Results from a multicentre evaluation of plug use for left ventricular assist device explantation

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Results from a multicentre evaluation of plug use for left ventricular assist device explantation. / Potapov, Evgenij V; Politis, Nikolaos; Karck, Matthias; Weyand, Michael; Tandler, René; Walther, Thomas; Emrich, Fabian; Reichenspurrner, Hermann; Bernhardt, Alexander; Barten, Markus J; Svenarud, Peter; Gummert, Jan; Sef, Davorin; Doenst, Torsten; Tsyganenko, Dmytro; Loforte, Antonio; Schoenrath, Felix; Falk, Volkmar.

In: INTERACT CARDIOV TH, Vol. 34, No. 4, 31.03.2022, p. 683-690.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Potapov, EV, Politis, N, Karck, M, Weyand, M, Tandler, R, Walther, T, Emrich, F, Reichenspurrner, H, Bernhardt, A, Barten, MJ, Svenarud, P, Gummert, J, Sef, D, Doenst, T, Tsyganenko, D, Loforte, A, Schoenrath, F & Falk, V 2022, 'Results from a multicentre evaluation of plug use for left ventricular assist device explantation', INTERACT CARDIOV TH, vol. 34, no. 4, pp. 683-690. https://doi.org/10.1093/icvts/ivab344

APA

Potapov, E. V., Politis, N., Karck, M., Weyand, M., Tandler, R., Walther, T., Emrich, F., Reichenspurrner, H., Bernhardt, A., Barten, M. J., Svenarud, P., Gummert, J., Sef, D., Doenst, T., Tsyganenko, D., Loforte, A., Schoenrath, F., & Falk, V. (2022). Results from a multicentre evaluation of plug use for left ventricular assist device explantation. INTERACT CARDIOV TH, 34(4), 683-690. https://doi.org/10.1093/icvts/ivab344

Vancouver

Potapov EV, Politis N, Karck M, Weyand M, Tandler R, Walther T et al. Results from a multicentre evaluation of plug use for left ventricular assist device explantation. INTERACT CARDIOV TH. 2022 Mar 31;34(4):683-690. https://doi.org/10.1093/icvts/ivab344

Bibtex

@article{a669e0a45a2f48a09d4c5ef72b0ac7c5,
title = "Results from a multicentre evaluation of plug use for left ventricular assist device explantation",
abstract = "OBJECTIVES: Myocardial recovery allows for left ventricular assist device (LVAD) explantations after long-term support. Several surgical approaches, including interventional decommissioning, off-pump explantation using a custom-made plug and complete LVAD removal through redo sternotomy, have been described. We present the results from an evaluation of the long-term follow-up of patients who received a titanium sintered plug after LVAD explantation.METHODS: We performed a retrospective, European, multicentre analysis of patients who received a titanium sintered plug to seal the apical fixation ring after LVAD explantation. Data were collected from a questionnaire that included demographics, procedural details and follow-up information.RESULTS: Out of 54 contacted centres in 12 countries (n = 179 patients), a total of 68 patients were successfully included in the study. The median follow-up was 34 months (interquartile range: 17-58.5 months); 57 (84%) patients had >1-year follow-up. At the time of the last follow-up, 55 (81%) patients were alive, with a Kaplan-Meier 1-year survival of 90.1% (95% confidence interval: 84.0-98.1%) and a 5-year survival of 80.0% (95% confidence interval: 68.4-92.9%). One patient (1.5%) developed a plug infection originating from an infected part of the incorporated driveline and, after complete removal, is currently in good condition. No postoperative stroke has been reported after plug implantation.CONCLUSIONS: In this European multicentre study, the use of a custom-made titanium plug to close the apical fixation ring after LVAD explantation resulted in a low incidence of plug-related complications. With the volume of patients undergoing LVAD explantations after myocardial recovery increasing, the plug has evolved as a simple alternative to more invasive device explantation procedures or decommissioning with a high risk for infection of the remaining system or stroke.",
author = "Potapov, {Evgenij V} and Nikolaos Politis and Matthias Karck and Michael Weyand and Ren{\'e} Tandler and Thomas Walther and Fabian Emrich and Hermann Reichenspurrner and Alexander Bernhardt and Barten, {Markus J} and Peter Svenarud and Jan Gummert and Davorin Sef and Torsten Doenst and Dmytro Tsyganenko and Antonio Loforte and Felix Schoenrath and Volkmar Falk",
note = "{\textcopyright} The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.",
year = "2022",
month = mar,
day = "31",
doi = "10.1093/icvts/ivab344",
language = "English",
volume = "34",
pages = "683--690",
journal = "INTERACT CARDIOV TH",
issn = "1569-9293",
publisher = "European Association for Cardio-Thoracic Surgery",
number = "4",

}

RIS

TY - JOUR

T1 - Results from a multicentre evaluation of plug use for left ventricular assist device explantation

AU - Potapov, Evgenij V

AU - Politis, Nikolaos

AU - Karck, Matthias

AU - Weyand, Michael

AU - Tandler, René

AU - Walther, Thomas

AU - Emrich, Fabian

AU - Reichenspurrner, Hermann

AU - Bernhardt, Alexander

AU - Barten, Markus J

AU - Svenarud, Peter

AU - Gummert, Jan

AU - Sef, Davorin

AU - Doenst, Torsten

AU - Tsyganenko, Dmytro

AU - Loforte, Antonio

AU - Schoenrath, Felix

AU - Falk, Volkmar

N1 - © The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.

PY - 2022/3/31

Y1 - 2022/3/31

N2 - OBJECTIVES: Myocardial recovery allows for left ventricular assist device (LVAD) explantations after long-term support. Several surgical approaches, including interventional decommissioning, off-pump explantation using a custom-made plug and complete LVAD removal through redo sternotomy, have been described. We present the results from an evaluation of the long-term follow-up of patients who received a titanium sintered plug after LVAD explantation.METHODS: We performed a retrospective, European, multicentre analysis of patients who received a titanium sintered plug to seal the apical fixation ring after LVAD explantation. Data were collected from a questionnaire that included demographics, procedural details and follow-up information.RESULTS: Out of 54 contacted centres in 12 countries (n = 179 patients), a total of 68 patients were successfully included in the study. The median follow-up was 34 months (interquartile range: 17-58.5 months); 57 (84%) patients had >1-year follow-up. At the time of the last follow-up, 55 (81%) patients were alive, with a Kaplan-Meier 1-year survival of 90.1% (95% confidence interval: 84.0-98.1%) and a 5-year survival of 80.0% (95% confidence interval: 68.4-92.9%). One patient (1.5%) developed a plug infection originating from an infected part of the incorporated driveline and, after complete removal, is currently in good condition. No postoperative stroke has been reported after plug implantation.CONCLUSIONS: In this European multicentre study, the use of a custom-made titanium plug to close the apical fixation ring after LVAD explantation resulted in a low incidence of plug-related complications. With the volume of patients undergoing LVAD explantations after myocardial recovery increasing, the plug has evolved as a simple alternative to more invasive device explantation procedures or decommissioning with a high risk for infection of the remaining system or stroke.

AB - OBJECTIVES: Myocardial recovery allows for left ventricular assist device (LVAD) explantations after long-term support. Several surgical approaches, including interventional decommissioning, off-pump explantation using a custom-made plug and complete LVAD removal through redo sternotomy, have been described. We present the results from an evaluation of the long-term follow-up of patients who received a titanium sintered plug after LVAD explantation.METHODS: We performed a retrospective, European, multicentre analysis of patients who received a titanium sintered plug to seal the apical fixation ring after LVAD explantation. Data were collected from a questionnaire that included demographics, procedural details and follow-up information.RESULTS: Out of 54 contacted centres in 12 countries (n = 179 patients), a total of 68 patients were successfully included in the study. The median follow-up was 34 months (interquartile range: 17-58.5 months); 57 (84%) patients had >1-year follow-up. At the time of the last follow-up, 55 (81%) patients were alive, with a Kaplan-Meier 1-year survival of 90.1% (95% confidence interval: 84.0-98.1%) and a 5-year survival of 80.0% (95% confidence interval: 68.4-92.9%). One patient (1.5%) developed a plug infection originating from an infected part of the incorporated driveline and, after complete removal, is currently in good condition. No postoperative stroke has been reported after plug implantation.CONCLUSIONS: In this European multicentre study, the use of a custom-made titanium plug to close the apical fixation ring after LVAD explantation resulted in a low incidence of plug-related complications. With the volume of patients undergoing LVAD explantations after myocardial recovery increasing, the plug has evolved as a simple alternative to more invasive device explantation procedures or decommissioning with a high risk for infection of the remaining system or stroke.

U2 - 10.1093/icvts/ivab344

DO - 10.1093/icvts/ivab344

M3 - SCORING: Journal article

C2 - 34888681

VL - 34

SP - 683

EP - 690

JO - INTERACT CARDIOV TH

JF - INTERACT CARDIOV TH

SN - 1569-9293

IS - 4

ER -