Response of plasma beta-endorphin immunoreactivity to d-amphetamine and placebo in schizophrenic patients.
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Response of plasma beta-endorphin immunoreactivity to d-amphetamine and placebo in schizophrenic patients. / Schulz, S C; van Kammen, D P; Pickar, D; Cohen, M R; Naber, Dieter.
In: PSYCHIAT RES, Vol. 7, No. 2, 2, 1982, p. 171-178.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Response of plasma beta-endorphin immunoreactivity to d-amphetamine and placebo in schizophrenic patients.
AU - Schulz, S C
AU - van Kammen, D P
AU - Pickar, D
AU - Cohen, M R
AU - Naber, Dieter
PY - 1982
Y1 - 1982
N2 - The response of plasma beta-endorphin (ir) to infusions of randomly assigned d-amphetamine (20 mg) and placebo was studied in eight schizophrenic patients. Although there was no statistically significant difference between the response to d-amphetamine and placebo, significant increases in plasma beta-endorphin (ir) levels were observed following each infusion. Although heterogeneity in beta-endorphin (ir) response was observed, individual differences did not relate to clinical variables such as abnormalities on computed tomography or "process-reactive" distinctions. An excessive beta-endorphin response to placebo in schizophrenia is discussed.
AB - The response of plasma beta-endorphin (ir) to infusions of randomly assigned d-amphetamine (20 mg) and placebo was studied in eight schizophrenic patients. Although there was no statistically significant difference between the response to d-amphetamine and placebo, significant increases in plasma beta-endorphin (ir) levels were observed following each infusion. Although heterogeneity in beta-endorphin (ir) response was observed, individual differences did not relate to clinical variables such as abnormalities on computed tomography or "process-reactive" distinctions. An excessive beta-endorphin response to placebo in schizophrenia is discussed.
M3 - SCORING: Zeitschriftenaufsatz
VL - 7
SP - 171
EP - 178
JO - PSYCHIAT RES
JF - PSYCHIAT RES
SN - 0165-1781
IS - 2
M1 - 2
ER -