Research ExplorerPublicationsResection of small plexiform neurofibromas in neurofibromato...

Resection of small plexiform neurofibromas in neurofibromatosis type 1 children

Standard

Resection of small plexiform neurofibromas in neurofibromatosis type 1 children. / Friedrich, Reinhard E; Schmelzle, Rainer; Hartmann, Melanie; Fünsterer, Carsten; Mautner, Victor-F.

In: WORLD J SURG ONCOL, Vol. 3, No. 1, 31.01.2005, p. 6.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Friedrich, RE, Schmelzle, R, Hartmann, M, Fünsterer, C & Mautner, V-F 2005, 'Resection of small plexiform neurofibromas in neurofibromatosis type 1 children', WORLD J SURG ONCOL, vol. 3, no. 1, pp. 6. https://doi.org/10.1186/1477-7819-3-6

APA

Friedrich, R. E., Schmelzle, R., Hartmann, M., Fünsterer, C., & Mautner, V-F. (2005). Resection of small plexiform neurofibromas in neurofibromatosis type 1 children. WORLD J SURG ONCOL, 3(1), 6. https://doi.org/10.1186/1477-7819-3-6

Vancouver

Friedrich RE, Schmelzle R, Hartmann M, Fünsterer C, Mautner V-F. Resection of small plexiform neurofibromas in neurofibromatosis type 1 children. WORLD J SURG ONCOL. 2005 Jan 31;3(1):6. https://doi.org/10.1186/1477-7819-3-6

Bibtex

@article{1fa7ad579ee64397b5ce64967699bb0c,
title = "Resection of small plexiform neurofibromas in neurofibromatosis type 1 children",
abstract = "BACKGROUND: Plexiform neurofibromas (PNF) are benign tumors of the peripheral nerve which mostly develop in patients with neurofibromatosis type 1 (NF1). Surgical interventions are usually not applied to children with small tumors. These are rather restricted to debulking of larger tumors in adults that cause clinical complications or aesthetic disfigurement. In most cases, a total resection of PNF is not possible due to the network-like growth of the tumors. PATIENTS AND METHODS: Early surgical intervention was carried out for 9 small PNFs in 7 NF1 children. Tumor resection was performed following the graphical delineation of the affected skin and according the MRI findings. RESULTS: Total resection was achieved for all 9 PNF without causing any neurological or organic deficit. Annual magnetic resonance tomography over a period of four years did not reveal any relapse of the tumors. CONCLUSIONS: Early surgical intervention for small superficial PNFs in NF1 children have various advantages and may especially be considered a strategy to prevent progression.",
author = "Friedrich, {Reinhard E} and Rainer Schmelzle and Melanie Hartmann and Carsten F{\"u}nsterer and Victor-F Mautner",
year = "2005",
month = jan,
day = "31",
doi = "10.1186/1477-7819-3-6",
language = "English",
volume = "3",
pages = "6",
journal = "WORLD J SURG ONCOL",
issn = "1477-7819",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Resection of small plexiform neurofibromas in neurofibromatosis type 1 children

AU - Friedrich, Reinhard E

AU - Schmelzle, Rainer

AU - Hartmann, Melanie

AU - Fünsterer, Carsten

AU - Mautner, Victor-F

PY - 2005/1/31

Y1 - 2005/1/31

N2 - BACKGROUND: Plexiform neurofibromas (PNF) are benign tumors of the peripheral nerve which mostly develop in patients with neurofibromatosis type 1 (NF1). Surgical interventions are usually not applied to children with small tumors. These are rather restricted to debulking of larger tumors in adults that cause clinical complications or aesthetic disfigurement. In most cases, a total resection of PNF is not possible due to the network-like growth of the tumors. PATIENTS AND METHODS: Early surgical intervention was carried out for 9 small PNFs in 7 NF1 children. Tumor resection was performed following the graphical delineation of the affected skin and according the MRI findings. RESULTS: Total resection was achieved for all 9 PNF without causing any neurological or organic deficit. Annual magnetic resonance tomography over a period of four years did not reveal any relapse of the tumors. CONCLUSIONS: Early surgical intervention for small superficial PNFs in NF1 children have various advantages and may especially be considered a strategy to prevent progression.

AB - BACKGROUND: Plexiform neurofibromas (PNF) are benign tumors of the peripheral nerve which mostly develop in patients with neurofibromatosis type 1 (NF1). Surgical interventions are usually not applied to children with small tumors. These are rather restricted to debulking of larger tumors in adults that cause clinical complications or aesthetic disfigurement. In most cases, a total resection of PNF is not possible due to the network-like growth of the tumors. PATIENTS AND METHODS: Early surgical intervention was carried out for 9 small PNFs in 7 NF1 children. Tumor resection was performed following the graphical delineation of the affected skin and according the MRI findings. RESULTS: Total resection was achieved for all 9 PNF without causing any neurological or organic deficit. Annual magnetic resonance tomography over a period of four years did not reveal any relapse of the tumors. CONCLUSIONS: Early surgical intervention for small superficial PNFs in NF1 children have various advantages and may especially be considered a strategy to prevent progression.

U2 - 10.1186/1477-7819-3-6

DO - 10.1186/1477-7819-3-6

M3 - SCORING: Journal article

C2 - 15683544

VL - 3

SP - 6

JO - WORLD J SURG ONCOL

JF - WORLD J SURG ONCOL

SN - 1477-7819

IS - 1

ER -