Research ExplorerPublicationsResearch priorities to achieve universal access to hepatitis...

Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs

Standard

Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs. / Grebely, Jason; Bruneau, Julie; Lazarus, Jeffrey V; Dalgard, Olav; Bruggmann, Philip; Treloar, Carla; Hickman, Matthew; Hellard, Margaret; Roberts, Teri; Crooks, Levinia; Midgard, Håvard; Larney, Sarah; Degenhardt, Louisa; Alho, Hannu; Byrne, Jude; Dillon, John F; Feld, Jordan J; Foster, Graham; Goldberg, David; Lloyd, Andrew R; Reimer, Jens; Robaeys, Geert; Torrens, Marta; Wright, Nat; Maremmani, Icro; Norton, Brianna L; Litwin, Alain H; Dore, Gregory J; International Network on Hepatitis in Substance Users.

In: INT J DRUG POLICY, Vol. 47, 09.2017, p. 51-60.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Grebely, J, Bruneau, J, Lazarus, JV, Dalgard, O, Bruggmann, P, Treloar, C, Hickman, M, Hellard, M, Roberts, T, Crooks, L, Midgard, H, Larney, S, Degenhardt, L, Alho, H, Byrne, J, Dillon, JF, Feld, JJ, Foster, G, Goldberg, D, Lloyd, AR, Reimer, J, Robaeys, G, Torrens, M, Wright, N, Maremmani, I, Norton, BL, Litwin, AH, Dore, GJ & International Network on Hepatitis in Substance Users 2017, 'Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs', INT J DRUG POLICY, vol. 47, pp. 51-60. https://doi.org/10.1016/j.drugpo.2017.05.019

APA

Grebely, J., Bruneau, J., Lazarus, J. V., Dalgard, O., Bruggmann, P., Treloar, C., Hickman, M., Hellard, M., Roberts, T., Crooks, L., Midgard, H., Larney, S., Degenhardt, L., Alho, H., Byrne, J., Dillon, J. F., Feld, J. J., Foster, G., Goldberg, D., ... International Network on Hepatitis in Substance Users (2017). Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs. INT J DRUG POLICY, 47, 51-60. https://doi.org/10.1016/j.drugpo.2017.05.019

Vancouver

Grebely J, Bruneau J, Lazarus JV, Dalgard O, Bruggmann P, Treloar C et al. Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs. INT J DRUG POLICY. 2017 Sep;47:51-60. https://doi.org/10.1016/j.drugpo.2017.05.019

Bibtex

@article{eb445f4fb575491c9f66f26b6ea8048c,
title = "Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs",
abstract = "Globally, it is estimated that 71.1 million people have chronic hepatitis C virus (HCV) infection, including an estimated 7.5 million people who have recently injected drugs (PWID). There is an additional large, but unquantified, burden among those PWID who have ceased injecting. The incidence of HCV infection among current PWID also remains high in many settings. Morbidity and mortality due to liver disease among PWID with HCV infection continues to increase, despite the advent of well-tolerated, simple interferon-free direct-acting antiviral (DAA) HCV regimens with cure rates >95%. As a result of this important clinical breakthrough, there is potential to reverse the rising burden of advanced liver disease with increased treatment and strive for HCV elimination among PWID. Unfortunately, there are many gaps in knowledge that represent barriers to effective prevention and management of HCV among PWID. The Kirby Institute, UNSW Sydney and the International Network on Hepatitis in Substance Users (INHSU) established an expert round table panel to assess current research gaps and establish future research priorities for the prevention and management of HCV among PWID. This round table consisted of a one-day workshop held on 6 September, 2016, in Oslo, Norway, prior to the International Symposium on Hepatitis in Substance Users (INHSU 2016). International experts in drug and alcohol, infectious diseases, and hepatology were brought together to discuss the available scientific evidence, gaps in research, and develop research priorities. Topics for discussion included the epidemiology of injecting drug use, HCV, and HIV among PWID, HCV prevention, HCV testing, linkage to HCV care and treatment, DAA treatment for HCV infection, and reinfection following successful treatment. This paper highlights the outcomes of the roundtable discussion focused on future research priorities for enhancing HCV prevention, testing, linkage to care and DAA treatment for PWID as we strive for global elimination of HCV infection.",
keywords = "Journal Article",
author = "Jason Grebely and Julie Bruneau and Lazarus, {Jeffrey V} and Olav Dalgard and Philip Bruggmann and Carla Treloar and Matthew Hickman and Margaret Hellard and Teri Roberts and Levinia Crooks and H{\aa}vard Midgard and Sarah Larney and Louisa Degenhardt and Hannu Alho and Jude Byrne and Dillon, {John F} and Feld, {Jordan J} and Graham Foster and David Goldberg and Lloyd, {Andrew R} and Jens Reimer and Geert Robaeys and Marta Torrens and Nat Wright and Icro Maremmani and Norton, {Brianna L} and Litwin, {Alain H} and Dore, {Gregory J} and {International Network on Hepatitis in Substance Users}",
note = "Copyright {\textcopyright} 2017 Elsevier B.V. All rights reserved.",
year = "2017",
month = sep,
doi = "10.1016/j.drugpo.2017.05.019",
language = "English",
volume = "47",
pages = "51--60",
journal = "INT J DRUG POLICY",
issn = "0955-3959",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs

AU - Grebely, Jason

AU - Bruneau, Julie

AU - Lazarus, Jeffrey V

AU - Dalgard, Olav

AU - Bruggmann, Philip

AU - Treloar, Carla

AU - Hickman, Matthew

AU - Hellard, Margaret

AU - Roberts, Teri

AU - Crooks, Levinia

AU - Midgard, Håvard

AU - Larney, Sarah

AU - Degenhardt, Louisa

AU - Alho, Hannu

AU - Byrne, Jude

AU - Dillon, John F

AU - Feld, Jordan J

AU - Foster, Graham

AU - Goldberg, David

AU - Lloyd, Andrew R

AU - Reimer, Jens

AU - Robaeys, Geert

AU - Torrens, Marta

AU - Wright, Nat

AU - Maremmani, Icro

AU - Norton, Brianna L

AU - Litwin, Alain H

AU - Dore, Gregory J

AU - International Network on Hepatitis in Substance Users

N1 - Copyright © 2017 Elsevier B.V. All rights reserved.

PY - 2017/9

Y1 - 2017/9

N2 - Globally, it is estimated that 71.1 million people have chronic hepatitis C virus (HCV) infection, including an estimated 7.5 million people who have recently injected drugs (PWID). There is an additional large, but unquantified, burden among those PWID who have ceased injecting. The incidence of HCV infection among current PWID also remains high in many settings. Morbidity and mortality due to liver disease among PWID with HCV infection continues to increase, despite the advent of well-tolerated, simple interferon-free direct-acting antiviral (DAA) HCV regimens with cure rates >95%. As a result of this important clinical breakthrough, there is potential to reverse the rising burden of advanced liver disease with increased treatment and strive for HCV elimination among PWID. Unfortunately, there are many gaps in knowledge that represent barriers to effective prevention and management of HCV among PWID. The Kirby Institute, UNSW Sydney and the International Network on Hepatitis in Substance Users (INHSU) established an expert round table panel to assess current research gaps and establish future research priorities for the prevention and management of HCV among PWID. This round table consisted of a one-day workshop held on 6 September, 2016, in Oslo, Norway, prior to the International Symposium on Hepatitis in Substance Users (INHSU 2016). International experts in drug and alcohol, infectious diseases, and hepatology were brought together to discuss the available scientific evidence, gaps in research, and develop research priorities. Topics for discussion included the epidemiology of injecting drug use, HCV, and HIV among PWID, HCV prevention, HCV testing, linkage to HCV care and treatment, DAA treatment for HCV infection, and reinfection following successful treatment. This paper highlights the outcomes of the roundtable discussion focused on future research priorities for enhancing HCV prevention, testing, linkage to care and DAA treatment for PWID as we strive for global elimination of HCV infection.

AB - Globally, it is estimated that 71.1 million people have chronic hepatitis C virus (HCV) infection, including an estimated 7.5 million people who have recently injected drugs (PWID). There is an additional large, but unquantified, burden among those PWID who have ceased injecting. The incidence of HCV infection among current PWID also remains high in many settings. Morbidity and mortality due to liver disease among PWID with HCV infection continues to increase, despite the advent of well-tolerated, simple interferon-free direct-acting antiviral (DAA) HCV regimens with cure rates >95%. As a result of this important clinical breakthrough, there is potential to reverse the rising burden of advanced liver disease with increased treatment and strive for HCV elimination among PWID. Unfortunately, there are many gaps in knowledge that represent barriers to effective prevention and management of HCV among PWID. The Kirby Institute, UNSW Sydney and the International Network on Hepatitis in Substance Users (INHSU) established an expert round table panel to assess current research gaps and establish future research priorities for the prevention and management of HCV among PWID. This round table consisted of a one-day workshop held on 6 September, 2016, in Oslo, Norway, prior to the International Symposium on Hepatitis in Substance Users (INHSU 2016). International experts in drug and alcohol, infectious diseases, and hepatology were brought together to discuss the available scientific evidence, gaps in research, and develop research priorities. Topics for discussion included the epidemiology of injecting drug use, HCV, and HIV among PWID, HCV prevention, HCV testing, linkage to HCV care and treatment, DAA treatment for HCV infection, and reinfection following successful treatment. This paper highlights the outcomes of the roundtable discussion focused on future research priorities for enhancing HCV prevention, testing, linkage to care and DAA treatment for PWID as we strive for global elimination of HCV infection.

KW - Journal Article

U2 - 10.1016/j.drugpo.2017.05.019

DO - 10.1016/j.drugpo.2017.05.019

M3 - SCORING: Journal article

C2 - 28683982

VL - 47

SP - 51

EP - 60

JO - INT J DRUG POLICY

JF - INT J DRUG POLICY

SN - 0955-3959

ER -