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Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dysfunction

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Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dysfunction. / Landes, Uri; Webb, John G; De Backer, Ole; Sondergaard, Lars; Abdel-Wahab, Mohamed; Crusius, Lisa; Kim, Won-Keun; Hamm, Christian; Buzzatti, Nicola; Montorfano, Matteo; Ludwig, Sebastian; Schofer, Niklas; Voigtlaender, Lisa; Guerrero, Mayra; El Sabbagh, Abdallah; Rodés-Cabau, Josep; Guimaraes, Leonardo; Kornowski, Ran; Codner, Pablo; Okuno, Taishi; Pilgrim, Thomas; Fiorina, Claudia; Colombo, Antonio; Mangieri, Antonio; Eltchaninoff, Helene; Nombela-Franco, Luis; Van Wiechen, Maarten P H; Van Mieghem, Nicolas M; Tchétché, Didier; Schoels, Wolfgang H; Kullmer, Matthias; Tamburino, Corrado; Sinning, Jan-Malte; Al-Kassou, Baravan; Perlman, Gidon Y; Danenberg, Haim; Ielasi, Alfonso; Fraccaro, Chiara; Tarantini, Giuseppe; De Marco, Federico; Witberg, Guy; Redwood, Simon R; Lisko, John C; Babaliaros, Vasilis C; Laine, Mika; Nerla, Roberto; Castriota, Fausto; Finkelstein, Ariel; Loewenstein, Itamar; Eitan, Amnon; Jaffe, Ronen; Ruile, Philipp; Neumann, Franz J; Piazza, Nicolo; Alosaimi, Hind; Sievert, Horst; Sievert, Kolja; Russo, Marco; Andreas, Martin; Bunc, Matjaz; Latib, Azeem; Govdfrey, Rebecca; Hildick-Smith, David; Sathananthan, Janarthanan; Hensey, Mark; Alkhodair, Abdullah; Blanke, Philipp; Leipsic, Jonathon; Wood, David A; Nazif, Tamim M; Kodali, Susheel; Leon, Martin B; Barbanti, Marco; Redo-TAVR Registry.

In: J AM COLL CARDIOL, Vol. 75, No. 16, 28.04.2020, p. 1882-1893.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Landes, U, Webb, JG, De Backer, O, Sondergaard, L, Abdel-Wahab, M, Crusius, L, Kim, W-K, Hamm, C, Buzzatti, N, Montorfano, M, Ludwig, S, Schofer, N, Voigtlaender, L, Guerrero, M, El Sabbagh, A, Rodés-Cabau, J, Guimaraes, L, Kornowski, R, Codner, P, Okuno, T, Pilgrim, T, Fiorina, C, Colombo, A, Mangieri, A, Eltchaninoff, H, Nombela-Franco, L, Van Wiechen, MPH, Van Mieghem, NM, Tchétché, D, Schoels, WH, Kullmer, M, Tamburino, C, Sinning, J-M, Al-Kassou, B, Perlman, GY, Danenberg, H, Ielasi, A, Fraccaro, C, Tarantini, G, De Marco, F, Witberg, G, Redwood, SR, Lisko, JC, Babaliaros, VC, Laine, M, Nerla, R, Castriota, F, Finkelstein, A, Loewenstein, I, Eitan, A, Jaffe, R, Ruile, P, Neumann, FJ, Piazza, N, Alosaimi, H, Sievert, H, Sievert, K, Russo, M, Andreas, M, Bunc, M, Latib, A, Govdfrey, R, Hildick-Smith, D, Sathananthan, J, Hensey, M, Alkhodair, A, Blanke, P, Leipsic, J, Wood, DA, Nazif, TM, Kodali, S, Leon, MB, Barbanti, M & Redo-TAVR Registry 2020, 'Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dysfunction', J AM COLL CARDIOL, vol. 75, no. 16, pp. 1882-1893. https://doi.org/10.1016/j.jacc.2020.02.051

APA

Landes, U., Webb, J. G., De Backer, O., Sondergaard, L., Abdel-Wahab, M., Crusius, L., Kim, W-K., Hamm, C., Buzzatti, N., Montorfano, M., Ludwig, S., Schofer, N., Voigtlaender, L., Guerrero, M., El Sabbagh, A., Rodés-Cabau, J., Guimaraes, L., Kornowski, R., Codner, P., ... Redo-TAVR Registry (2020). Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dysfunction. J AM COLL CARDIOL, 75(16), 1882-1893. https://doi.org/10.1016/j.jacc.2020.02.051

Vancouver

Landes U, Webb JG, De Backer O, Sondergaard L, Abdel-Wahab M, Crusius L et al. Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dysfunction. J AM COLL CARDIOL. 2020 Apr 28;75(16):1882-1893. https://doi.org/10.1016/j.jacc.2020.02.051

Bibtex

@article{af4fcb3ea82f4c739fa41ebd58fcabb7,
title = "Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dysfunction",
abstract = "BACKGROUND: Transcatheter aortic valve replacement (TAVR) use is increasing in patients with longer life expectancy, yet robust data on the durability of transcatheter heart valves (THVs) are limited. Redo-TAVR may play a key strategy in treating patients in whom THVs fail.OBJECTIVES: The authors sought to examine outcomes following redo-TAVR.METHODS: The Redo-TAVR registry collected data on consecutive patients who underwent redo-TAVR at 37 centers. Patients were classified as probable TAVR failure or probable THV failure if they presented within or beyond 1 year of their index TAVR, respectively.RESULTS: Among 63,876 TAVR procedures, 212 consecutive redo-TAVR procedures were identified (0.33%): 74 within and 138 beyond 1 year of the initial procedure. For these 2 groups, TAVR-to-redo-TAVR time was 68 (38 to 154) days and 5 (3 to 6) years. The indication for redo-TAVR was THV stenosis in 12 (16.2%) and 51 (37.0%) (p = 0.002) and regurgitation or combined stenosis-regurgitation in 62 (83.8%) and 86 (62.3%) (p = 0.028), respectively. Device success using VARC-2 criteria was achieved in 180 patients (85.1%); most failures were attributable to high residual gradients (14.1%) or regurgitation (8.9%). At 30-day and 1-year follow-up, residual gradients were 12.6 ± 7.5 mm Hg and 12.9 ± 9.0 mm Hg; valve area 1.63 ± 0.61 cm2 and 1.51 ± 0.57 cm2; and regurgitation ≤mild in 91% and 91%, respectively. Peri-procedural complication rates were low (3 stroke [1.4%], 7 valve malposition [3.3%], 2 coronary obstruction [0.9%], 20 new permanent pacemaker [9.6%], no mortality), and symptomatic improvement was substantial. Survival at 30 days was 94.6% and 98.5% (p = 0.101) and 83.6% and 88.3% (p = 0.335) at 1 year for patients presenting with early and late valve dysfunction, respectively.CONCLUSIONS: Redo-TAVR is a relatively safe and effective option for selected patients with valve dysfunction after TAVR. These results are important for applicability of TAVR in patients with long life expectancy in whom THV durability may be a concern.",
keywords = "Aged, Aortic Valve/surgery, Aortic Valve Insufficiency/diagnosis, Aortic Valve Stenosis/surgery, Equipment Failure Analysis, Female, Global Health, Heart Valve Prosthesis/adverse effects, Humans, Male, Outcome Assessment, Health Care, Postoperative Complications/diagnosis, Registries/statistics & numerical data, Reoperation/instrumentation, Survival Analysis, Symptom Assessment/statistics & numerical data, Transcatheter Aortic Valve Replacement/adverse effects",
author = "Uri Landes and Webb, {John G} and {De Backer}, Ole and Lars Sondergaard and Mohamed Abdel-Wahab and Lisa Crusius and Won-Keun Kim and Christian Hamm and Nicola Buzzatti and Matteo Montorfano and Sebastian Ludwig and Niklas Schofer and Lisa Voigtlaender and Mayra Guerrero and {El Sabbagh}, Abdallah and Josep Rod{\'e}s-Cabau and Leonardo Guimaraes and Ran Kornowski and Pablo Codner and Taishi Okuno and Thomas Pilgrim and Claudia Fiorina and Antonio Colombo and Antonio Mangieri and Helene Eltchaninoff and Luis Nombela-Franco and {Van Wiechen}, {Maarten P H} and {Van Mieghem}, {Nicolas M} and Didier Tch{\'e}tch{\'e} and Schoels, {Wolfgang H} and Matthias Kullmer and Corrado Tamburino and Jan-Malte Sinning and Baravan Al-Kassou and Perlman, {Gidon Y} and Haim Danenberg and Alfonso Ielasi and Chiara Fraccaro and Giuseppe Tarantini and {De Marco}, Federico and Guy Witberg and Redwood, {Simon R} and Lisko, {John C} and Babaliaros, {Vasilis C} and Mika Laine and Roberto Nerla and Fausto Castriota and Ariel Finkelstein and Itamar Loewenstein and Amnon Eitan and Ronen Jaffe and Philipp Ruile and Neumann, {Franz J} and Nicolo Piazza and Hind Alosaimi and Horst Sievert and Kolja Sievert and Marco Russo and Martin Andreas and Matjaz Bunc and Azeem Latib and Rebecca Govdfrey and David Hildick-Smith and Janarthanan Sathananthan and Mark Hensey and Abdullah Alkhodair and Philipp Blanke and Jonathon Leipsic and Wood, {David A} and Nazif, {Tamim M} and Susheel Kodali and Leon, {Martin B} and Marco Barbanti and {Redo-TAVR Registry}",
note = "Copyright {\textcopyright} 2020. Published by Elsevier Inc.",
year = "2020",
month = apr,
day = "28",
doi = "10.1016/j.jacc.2020.02.051",
language = "English",
volume = "75",
pages = "1882--1893",
journal = "J AM COLL CARDIOL",
issn = "0735-1097",
publisher = "Elsevier USA",
number = "16",

}

RIS

TY - JOUR

T1 - Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dysfunction

AU - Landes, Uri

AU - Webb, John G

AU - De Backer, Ole

AU - Sondergaard, Lars

AU - Abdel-Wahab, Mohamed

AU - Crusius, Lisa

AU - Kim, Won-Keun

AU - Hamm, Christian

AU - Buzzatti, Nicola

AU - Montorfano, Matteo

AU - Ludwig, Sebastian

AU - Schofer, Niklas

AU - Voigtlaender, Lisa

AU - Guerrero, Mayra

AU - El Sabbagh, Abdallah

AU - Rodés-Cabau, Josep

AU - Guimaraes, Leonardo

AU - Kornowski, Ran

AU - Codner, Pablo

AU - Okuno, Taishi

AU - Pilgrim, Thomas

AU - Fiorina, Claudia

AU - Colombo, Antonio

AU - Mangieri, Antonio

AU - Eltchaninoff, Helene

AU - Nombela-Franco, Luis

AU - Van Wiechen, Maarten P H

AU - Van Mieghem, Nicolas M

AU - Tchétché, Didier

AU - Schoels, Wolfgang H

AU - Kullmer, Matthias

AU - Tamburino, Corrado

AU - Sinning, Jan-Malte

AU - Al-Kassou, Baravan

AU - Perlman, Gidon Y

AU - Danenberg, Haim

AU - Ielasi, Alfonso

AU - Fraccaro, Chiara

AU - Tarantini, Giuseppe

AU - De Marco, Federico

AU - Witberg, Guy

AU - Redwood, Simon R

AU - Lisko, John C

AU - Babaliaros, Vasilis C

AU - Laine, Mika

AU - Nerla, Roberto

AU - Castriota, Fausto

AU - Finkelstein, Ariel

AU - Loewenstein, Itamar

AU - Eitan, Amnon

AU - Jaffe, Ronen

AU - Ruile, Philipp

AU - Neumann, Franz J

AU - Piazza, Nicolo

AU - Alosaimi, Hind

AU - Sievert, Horst

AU - Sievert, Kolja

AU - Russo, Marco

AU - Andreas, Martin

AU - Bunc, Matjaz

AU - Latib, Azeem

AU - Govdfrey, Rebecca

AU - Hildick-Smith, David

AU - Sathananthan, Janarthanan

AU - Hensey, Mark

AU - Alkhodair, Abdullah

AU - Blanke, Philipp

AU - Leipsic, Jonathon

AU - Wood, David A

AU - Nazif, Tamim M

AU - Kodali, Susheel

AU - Leon, Martin B

AU - Barbanti, Marco

AU - Redo-TAVR Registry

N1 - Copyright © 2020. Published by Elsevier Inc.

PY - 2020/4/28

Y1 - 2020/4/28

N2 - BACKGROUND: Transcatheter aortic valve replacement (TAVR) use is increasing in patients with longer life expectancy, yet robust data on the durability of transcatheter heart valves (THVs) are limited. Redo-TAVR may play a key strategy in treating patients in whom THVs fail.OBJECTIVES: The authors sought to examine outcomes following redo-TAVR.METHODS: The Redo-TAVR registry collected data on consecutive patients who underwent redo-TAVR at 37 centers. Patients were classified as probable TAVR failure or probable THV failure if they presented within or beyond 1 year of their index TAVR, respectively.RESULTS: Among 63,876 TAVR procedures, 212 consecutive redo-TAVR procedures were identified (0.33%): 74 within and 138 beyond 1 year of the initial procedure. For these 2 groups, TAVR-to-redo-TAVR time was 68 (38 to 154) days and 5 (3 to 6) years. The indication for redo-TAVR was THV stenosis in 12 (16.2%) and 51 (37.0%) (p = 0.002) and regurgitation or combined stenosis-regurgitation in 62 (83.8%) and 86 (62.3%) (p = 0.028), respectively. Device success using VARC-2 criteria was achieved in 180 patients (85.1%); most failures were attributable to high residual gradients (14.1%) or regurgitation (8.9%). At 30-day and 1-year follow-up, residual gradients were 12.6 ± 7.5 mm Hg and 12.9 ± 9.0 mm Hg; valve area 1.63 ± 0.61 cm2 and 1.51 ± 0.57 cm2; and regurgitation ≤mild in 91% and 91%, respectively. Peri-procedural complication rates were low (3 stroke [1.4%], 7 valve malposition [3.3%], 2 coronary obstruction [0.9%], 20 new permanent pacemaker [9.6%], no mortality), and symptomatic improvement was substantial. Survival at 30 days was 94.6% and 98.5% (p = 0.101) and 83.6% and 88.3% (p = 0.335) at 1 year for patients presenting with early and late valve dysfunction, respectively.CONCLUSIONS: Redo-TAVR is a relatively safe and effective option for selected patients with valve dysfunction after TAVR. These results are important for applicability of TAVR in patients with long life expectancy in whom THV durability may be a concern.

AB - BACKGROUND: Transcatheter aortic valve replacement (TAVR) use is increasing in patients with longer life expectancy, yet robust data on the durability of transcatheter heart valves (THVs) are limited. Redo-TAVR may play a key strategy in treating patients in whom THVs fail.OBJECTIVES: The authors sought to examine outcomes following redo-TAVR.METHODS: The Redo-TAVR registry collected data on consecutive patients who underwent redo-TAVR at 37 centers. Patients were classified as probable TAVR failure or probable THV failure if they presented within or beyond 1 year of their index TAVR, respectively.RESULTS: Among 63,876 TAVR procedures, 212 consecutive redo-TAVR procedures were identified (0.33%): 74 within and 138 beyond 1 year of the initial procedure. For these 2 groups, TAVR-to-redo-TAVR time was 68 (38 to 154) days and 5 (3 to 6) years. The indication for redo-TAVR was THV stenosis in 12 (16.2%) and 51 (37.0%) (p = 0.002) and regurgitation or combined stenosis-regurgitation in 62 (83.8%) and 86 (62.3%) (p = 0.028), respectively. Device success using VARC-2 criteria was achieved in 180 patients (85.1%); most failures were attributable to high residual gradients (14.1%) or regurgitation (8.9%). At 30-day and 1-year follow-up, residual gradients were 12.6 ± 7.5 mm Hg and 12.9 ± 9.0 mm Hg; valve area 1.63 ± 0.61 cm2 and 1.51 ± 0.57 cm2; and regurgitation ≤mild in 91% and 91%, respectively. Peri-procedural complication rates were low (3 stroke [1.4%], 7 valve malposition [3.3%], 2 coronary obstruction [0.9%], 20 new permanent pacemaker [9.6%], no mortality), and symptomatic improvement was substantial. Survival at 30 days was 94.6% and 98.5% (p = 0.101) and 83.6% and 88.3% (p = 0.335) at 1 year for patients presenting with early and late valve dysfunction, respectively.CONCLUSIONS: Redo-TAVR is a relatively safe and effective option for selected patients with valve dysfunction after TAVR. These results are important for applicability of TAVR in patients with long life expectancy in whom THV durability may be a concern.

KW - Aged

KW - Aortic Valve/surgery

KW - Aortic Valve Insufficiency/diagnosis

KW - Aortic Valve Stenosis/surgery

KW - Equipment Failure Analysis

KW - Female

KW - Global Health

KW - Heart Valve Prosthesis/adverse effects

KW - Humans

KW - Male

KW - Outcome Assessment, Health Care

KW - Postoperative Complications/diagnosis

KW - Registries/statistics & numerical data

KW - Reoperation/instrumentation

KW - Survival Analysis

KW - Symptom Assessment/statistics & numerical data

KW - Transcatheter Aortic Valve Replacement/adverse effects

U2 - 10.1016/j.jacc.2020.02.051

DO - 10.1016/j.jacc.2020.02.051

M3 - SCORING: Journal article

C2 - 32327098

VL - 75

SP - 1882

EP - 1893

JO - J AM COLL CARDIOL

JF - J AM COLL CARDIOL

SN - 0735-1097

IS - 16

ER -