Regulation of excitability by potassium channels.
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Regulation of excitability by potassium channels. / Pongs, Olaf.
In: Results Probl Cell Differ, Vol. 44, 2008, p. 145-161.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Regulation of excitability by potassium channels.
AU - Pongs, Olaf
PY - 2008
Y1 - 2008
N2 - Neurons express a large number of different voltage-gated potassium (Kv) channels with distinct biophysical and biochemical properties. Possibly, this diversity reflects the need to regulate and fine-tune neuronal excitability at various levels of complexity in space and time. In this context, Kv channels operating in the subthreshold range of action- potential firing are of particular interest. It is likely that these Kv channels play a prominent role in both propagating and integrating dendritic signaling, as well as axonal action-potential firing and propagation.
AB - Neurons express a large number of different voltage-gated potassium (Kv) channels with distinct biophysical and biochemical properties. Possibly, this diversity reflects the need to regulate and fine-tune neuronal excitability at various levels of complexity in space and time. In this context, Kv channels operating in the subthreshold range of action- potential firing are of particular interest. It is likely that these Kv channels play a prominent role in both propagating and integrating dendritic signaling, as well as axonal action-potential firing and propagation.
M3 - SCORING: Zeitschriftenaufsatz
VL - 44
SP - 145
EP - 161
ER -
