Research ExplorerPublicationsReduced-intensity conditioning versus standard conditioning ...

Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open-label randomised phase 3 trial.

Standard

Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open-label randomised phase 3 trial. / Bornhäuser, Martin; Kienast, Joachim; Trenschel, Rudolf; Burchert, Andreas; Hegenbart, Ute; Stadler, Michael; Baurmann, Herrad; Schäfer-Eckart, Kerstin; Holler, Ernst; Kröger, Nicolaus; Schmid, Christoph; Einsele, Herrmann; Kiehl, Michael G; Hiddemann, Wolfgang; Schwerdtfeger, Rainer; Buchholz, Stefanie; Dreger, Peter; Neubauer, Andreas; Berdel, Wolfgang E; Ehninger, Gerhard; Beelen, Dietrich W; Schetelig, Johannes; Stelljes, Matthias.

In: LANCET ONCOL, Vol. 13, No. 10, 10, 01.10.2012, p. 1035-1044.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Bornhäuser, M, Kienast, J, Trenschel, R, Burchert, A, Hegenbart, U, Stadler, M, Baurmann, H, Schäfer-Eckart, K, Holler, E, Kröger, N, Schmid, C, Einsele, H, Kiehl, MG, Hiddemann, W, Schwerdtfeger, R, Buchholz, S, Dreger, P, Neubauer, A, Berdel, WE, Ehninger, G, Beelen, DW, Schetelig, J & Stelljes, M 2012, 'Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open-label randomised phase 3 trial.', LANCET ONCOL, vol. 13, no. 10, 10, pp. 1035-1044. https://doi.org/10.1016/S1470-2045(12)70349-2

APA

Bornhäuser, M., Kienast, J., Trenschel, R., Burchert, A., Hegenbart, U., Stadler, M., Baurmann, H., Schäfer-Eckart, K., Holler, E., Kröger, N., Schmid, C., Einsele, H., Kiehl, M. G., Hiddemann, W., Schwerdtfeger, R., Buchholz, S., Dreger, P., Neubauer, A., Berdel, W. E., ... Stelljes, M. (2012). Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open-label randomised phase 3 trial. LANCET ONCOL, 13(10), 1035-1044. [10]. https://doi.org/10.1016/S1470-2045(12)70349-2

Vancouver

Bornhäuser M, Kienast J, Trenschel R, Burchert A, Hegenbart U, Stadler M et al. Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open-label randomised phase 3 trial. LANCET ONCOL. 2012 Oct 1;13(10):1035-1044. 10. https://doi.org/10.1016/S1470-2045(12)70349-2

Bibtex

@article{9f27537d75484bd1b33820a41a760436,
title = "Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open-label randomised phase 3 trial.",
abstract = "Reduced-intensity conditioning regimens have been developed to minimise early toxic effects and deaths after allogeneic haemopoietic cell transplantation. However, the efficacy of these regimens before this procedure has not been investigated in a randomised trial. In this prospective, open-label randomised phase 3 trial we compared a reduced-intensity fludarabine-based conditioning regimen with a standard regimen in patients with acute myeloid leukaemia in first complete remission.",
keywords = "Adult, Humans, Male, Female, Middle Aged, Adolescent, Young Adult, Prospective Studies, Transplantation, Homologous, *Hematopoietic Stem Cell Transplantation, Transplantation Conditioning/*methods, Leukemia, Myeloid, Acute/mortality/*therapy, Adult, Humans, Male, Female, Middle Aged, Adolescent, Young Adult, Prospective Studies, Transplantation, Homologous, *Hematopoietic Stem Cell Transplantation, Transplantation Conditioning/*methods, Leukemia, Myeloid, Acute/mortality/*therapy",
author = "Martin Bornh{\"a}user and Joachim Kienast and Rudolf Trenschel and Andreas Burchert and Ute Hegenbart and Michael Stadler and Herrad Baurmann and Kerstin Sch{\"a}fer-Eckart and Ernst Holler and Nicolaus Kr{\"o}ger and Christoph Schmid and Herrmann Einsele and Kiehl, {Michael G} and Wolfgang Hiddemann and Rainer Schwerdtfeger and Stefanie Buchholz and Peter Dreger and Andreas Neubauer and Berdel, {Wolfgang E} and Gerhard Ehninger and Beelen, {Dietrich W} and Johannes Schetelig and Matthias Stelljes",
note = "Copyright {\textcopyright} 2012 Elsevier Ltd. All rights reserved.",
year = "2012",
month = oct,
day = "1",
doi = "10.1016/S1470-2045(12)70349-2",
language = "English",
volume = "13",
pages = "1035--1044",
journal = "LANCET ONCOL",
issn = "1470-2045",
publisher = "Lancet Publishing Group",
number = "10",

}

RIS

TY - JOUR

T1 - Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open-label randomised phase 3 trial.

AU - Bornhäuser, Martin

AU - Kienast, Joachim

AU - Trenschel, Rudolf

AU - Burchert, Andreas

AU - Hegenbart, Ute

AU - Stadler, Michael

AU - Baurmann, Herrad

AU - Schäfer-Eckart, Kerstin

AU - Holler, Ernst

AU - Kröger, Nicolaus

AU - Schmid, Christoph

AU - Einsele, Herrmann

AU - Kiehl, Michael G

AU - Hiddemann, Wolfgang

AU - Schwerdtfeger, Rainer

AU - Buchholz, Stefanie

AU - Dreger, Peter

AU - Neubauer, Andreas

AU - Berdel, Wolfgang E

AU - Ehninger, Gerhard

AU - Beelen, Dietrich W

AU - Schetelig, Johannes

AU - Stelljes, Matthias

N1 - Copyright © 2012 Elsevier Ltd. All rights reserved.

PY - 2012/10/1

Y1 - 2012/10/1

N2 - Reduced-intensity conditioning regimens have been developed to minimise early toxic effects and deaths after allogeneic haemopoietic cell transplantation. However, the efficacy of these regimens before this procedure has not been investigated in a randomised trial. In this prospective, open-label randomised phase 3 trial we compared a reduced-intensity fludarabine-based conditioning regimen with a standard regimen in patients with acute myeloid leukaemia in first complete remission.

AB - Reduced-intensity conditioning regimens have been developed to minimise early toxic effects and deaths after allogeneic haemopoietic cell transplantation. However, the efficacy of these regimens before this procedure has not been investigated in a randomised trial. In this prospective, open-label randomised phase 3 trial we compared a reduced-intensity fludarabine-based conditioning regimen with a standard regimen in patients with acute myeloid leukaemia in first complete remission.

KW - Adult

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Adolescent

KW - Young Adult

KW - Prospective Studies

KW - Transplantation, Homologous

KW - Hematopoietic Stem Cell Transplantation

KW - Transplantation Conditioning/methods

KW - Leukemia, Myeloid, Acute/mortality/therapy

KW - Adult

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Adolescent

KW - Young Adult

KW - Prospective Studies

KW - Transplantation, Homologous

KW - Hematopoietic Stem Cell Transplantation

KW - Transplantation Conditioning/methods

KW - Leukemia, Myeloid, Acute/mortality/therapy

U2 - 10.1016/S1470-2045(12)70349-2

DO - 10.1016/S1470-2045(12)70349-2

M3 - SCORING: Journal article

C2 - 22959335

VL - 13

SP - 1035

EP - 1044

JO - LANCET ONCOL

JF - LANCET ONCOL

SN - 1470-2045

IS - 10

M1 - 10

ER -