Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.

  • Andreas Engert
  • Annette Plütschow
  • Hans Theodor Eich
  • Andreas Lohri
  • Bernd Dörken
  • Peter Borchmann
  • Bernhard Berger
  • Richard Greil
  • Kay C Willborn
  • Martin Wilhelm
  • Jürgen Debus
  • Michael J Eble
  • Martin Sökler
  • Antony Ho
  • Andreas Rank
  • Arnold Ganser
  • Lorenz Trümper
  • Carsten Bokemeyer
  • Hartmut Kirchner
  • Jörg Schubert
  • Zdenek Král
  • Michael Fuchs
  • Hans-Konrad Müller-Hermelink
  • Rolf-Peter Müller
  • Volker Diehl

Related Research units

Abstract

Whether it is possible to reduce the intensity of treatment in early (stage I or II) Hodgkin's lymphoma with a favorable prognosis remains unclear. We therefore conducted a multicenter, randomized trial comparing four treatment groups consisting of a combination chemotherapy regimen of two different intensities followed by involved-field radiation therapy at two different dose levels.

Bibliographical data

Original languageGerman
Article number7
ISSN0028-4793
Publication statusPublished - 2010
pubmed 20818855